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New drug aimed at treating apathy in dementia patients tested

NCT ID NCT04958031

Terminated Symptom relief Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a drug called CVL-871 to see if it is safe and can help reduce apathy (lack of motivation or interest) in people with dementia. The trial included 41 participants with mild to moderate dementia and clinically significant apathy. The main goal was to check for side effects and any changes in apathy symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease dementia frontotemporal dementia Lethargy Lewy body dementia vascular dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

APATHY IN DEMENTIA

Contacts and locations

Locations

  • Abington, Pennsylvania

    Abington, Pennsylvania, 19001, United States

  • Calgary, Alberta

    Calgary, Alberta, T2N 4N1, Canada

  • Charleston, South Carolina

    Charleston, South Carolina, 29403, United States

  • Columbus, Ohio

    Columbus, Ohio, 43210, United States

  • Decatur, Georgia

    Decatur, Georgia, 30030, United States

  • Delray Beach, Florida

    Delray Beach, Florida, 33445, United States

  • Fairfax, Virginia

    Fairfax, Virginia, 22031, United States

  • Little Rock, Arkansas

    Little Rock, Arkansas, 72114, United States

  • Miami, Florida

    Miami, Florida, 33122, United States

  • Miami, Florida

    Miami, Florida, 33180, United States

  • New Haven, Connecticut

    New Haven, Connecticut, 06510, United States

  • Orlando, Florida

    Orlando, Florida, 32819, United States

  • Plymouth, Massachusetts

    Plymouth, Massachusetts, 02360, United States

  • San Diego, California

    San Diego, California, 92123, United States

  • Santa Ana, California

    Santa Ana, California, 92705, United States

  • Scottsdale, Arizona

    Scottsdale, Arizona, 85258, United States

  • Staten Island, New York

    Staten Island, New York, 10312, United States

  • Toronto, Ontario

    Toronto, Ontario, M4N 3M5, Canada

  • Victoria, British Columbia

    Victoria, British Columbia, V8R 1J8, Canada

  • Wellington, Florida

    Wellington, Florida, 33414, United States

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