Can cosmetic injections boost confidence in jawline and neck?
NCT ID NCT07794891
First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time
Summary
This study tests whether injections of BOTOX and Juvéderm fillers can improve how people feel about their jawline and neck. Participants with moderate to severe neck lines, loss of jawline definition, or prominent neck bands will receive the injections. Researchers will measure satisfaction and psychological well-being through questionnaires and medical checks. The goal is to see if these treatments improve both appearance and emotional outlook.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Injections of onabotulinumtoxinA (BOTOX) and Juvéderm fillers (SKINVIVE, VOLUX, VOLUMA) into the jawline and neck
- What this could lead to
- If it works, this could support the use of these injections to improve satisfaction and psychological well-being related to jawline and neck appearance.
- What could go wrong
- This is a small, open-label study, so results may not apply broadly. Injections carry risks like bruising, swelling, or temporary muscle weakness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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22 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Moderate or severe transverse neck lines based on investigator's live assessment * Moderate or severe loss of jawline definition based on investigator's live assessment. * Moderate or severe platysma prominence based on investigator's live assessment. Exclusion Criteria: * History of or current medical condition that may put the subject at increased medical risk with exposure to BOTOX, or any other condition that might interfere with neuromuscular function. * History of or current symptoms of dysphagia. * History of severe allergies manifested by a history of anaphylaxis or history or presence of multiple severe allergies. * History of hypersensitivity or allergy to any botulinum toxin serotype, Streptococcal or gram-positive bacterial proteins, lidocaine, HA products, any other excipients or constituents of the study drug, device, and/or other products in the same class. * History of or tendency for keloid formation, hyperpigmentation, or hypertrophic scarring.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.