New hope for myeloma: experimental drug etentamig enters human trials

NCT ID NCT06892522

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental drug, etentamig, in people with multiple myeloma, a blood cancer. The drug is given alone or with other cancer medicines. The goal is to see if it is safe and works against the cancer. About 440 adults will take part at sites worldwide.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Etentamig (given alone or with lenalidomide, dexamethasone, daratumumab, or carfilzomib)

What this could lead to

If successful, this could provide a new treatment option for multiple myeloma, especially for patients whose cancer has returned or not responded to other therapies.

What could go wrong

This is an early-phase trial (phase 1/2), so safety and effectiveness are not yet proven. Side effects are possible, and the drug may not work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neoplasm plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Atrium Health Levine Cancer Institute /ID# 276193

    RECRUITING

    Charlotte, North Carolina, 28204-2990, United States

  • Atrium Health Wake Forest Baptist Medical Center /ID# 274847

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

  • Coffs Harbour Health Campus /ID# 272010

    RECRUITING

    Coffs Harbour, New South Wales, 2450, Australia

  • Colorado Blood Cancer Institute /ID# 273129

    RECRUITING

    Denver, Colorado, 80218, United States

  • Hadassah Medical Center-Hebrew University /ID# 271362

    RECRUITING

    Jerusalem, 91120, Israel

  • Hammersmith Hospital /ID# 274615

    RECRUITING

    London, England, W12 0HS, United Kingdom

  • Icon Cancer Care - South Brisbane /ID# 271836

    RECRUITING

    South Brisbane, Queensland, 4101, Australia

  • Moffitt Cancer Center /ID# 272628

    RECRUITING

    Tampa, Florida, 33612, United States

  • Nagoya City University Hospital /ID# 273529

    RECRUITING

    Nagoya, Aichi-ken, 467-8602, Japan

  • Oncology Hematology Care - Kenwood /ID# 272918

    RECRUITING

    Cincinnati, Ohio, 45236, United States

  • Peter MacCallum Cancer Centre /ID# 272024

    RECRUITING

    Melbourne, Victoria, 3000, Australia

  • Port Macquarie Base Hospital /ID# 275925

    RECRUITING

    Port Macquarie, New South Wales, 2444, Australia

  • Rabin Medical Center. /ID# 271365

    RECRUITING

    Petah Tikva, 4941492, Israel

  • Rambam Health Care Campus- Haifa /ID# 271364

    RECRUITING

    Haifa, 3525408, Israel

  • Royal Adelaide Hospital /ID# 272629

    RECRUITING

    Adelaide, South Australia, 5000, Australia

  • Soroka Medical Center /ID# 271367

    RECRUITING

    Beersheba, Southern District, 8410101, Israel

  • St Vincent's Hospital - Melbourne /ID# 276451

    RECRUITING

    Fitzroy, Victoria, 3065, Australia

  • The Chaim Sheba Medical Center /ID# 271366

    RECRUITING

    Ramat Gan, Tel Aviv, 5265601, Israel

  • The Perth Blood Institute - West Perth /ID# 272469

    RECRUITING

    West Perth, Western Australia, 6005, Australia

  • The University of Osaka Hospital /ID# 275791

    RECRUITING

    Suita-shi, Osaka, 565-0871, Japan

    Contact Phone: •••-•••-••••

  • University Hospital Kyoto Prefectural University of Medicine /ID# 275713

    RECRUITING

    Kyoto, Kyoto, 602-8566, Japan

  • University of North Carolina at Chapel Hill /ID# 274667

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

  • Weill Cornell Medical College /ID# 272517

    RECRUITING

    New York, New York, 10065, United States

  • Westmead Hospital /ID# 271880

    RECRUITING

    Westmead, New South Wales, 2145, Australia

  • Winship Cancer Institute of Emory University /ID# 274830

    RECRUITING

    Atlanta, Georgia, 30322, United States