New hope for myeloma: experimental drug etentamig enters human trials

NCT ID NCT06892522

Recruiting now Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times

Summary

This study tests an experimental drug, etentamig, in people with multiple myeloma, a blood cancer. The drug is given alone or with other cancer medicines. The goal is to see if it is safe and works against the cancer. About 440 adults will take part at sites worldwide.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Etentamig (given alone or with lenalidomide, dexamethasone, daratumumab, or carfilzomib)
What this could lead to: If successful, this could provide a new treatment option for multiple myeloma, especially for patients whose cancer has returned or not responded to other therapies.
What could go wrong: This is an early-phase trial (phase 1/2), so safety and effectiveness are not yet proven. Side effects are possible, and the drug may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

neoplasm plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE MYELOMA

Contacts and locations

Locations

Atrium Health Levine Cancer Institute /ID# 276193
RECRUITING

Charlotte, North Carolina, 28204-2990, United States
Atrium Health Wake Forest Baptist Medical Center /ID# 274847
RECRUITING

Winston-Salem, North Carolina, 27157, United States
City of Hope - Orange County Lennar Foundation Cancer Center /ID# 277911
RECRUITING

Irvine, California, 92618, United States
City of Hope National Medical Center /ID# 273132
RECRUITING

Duarte, California, 91010, United States
Coffs Harbour Health Campus /ID# 272010
RECRUITING

Coffs Harbour, New South Wales, 2450, Australia
Colorado Blood Cancer Institute /ID# 273129
RECRUITING

Denver, Colorado, 80218, United States
Hadassah Medical Center-Hebrew University /ID# 271362
RECRUITING

Jerusalem, 91120, Israel
Hammersmith Hospital /ID# 274615
RECRUITING

London, England, W12 0HS, United Kingdom
Huntsman Cancer Institute /ID# 272575
RECRUITING

Salt Lake City, Utah, 84112, United States
Icon Cancer Care - South Brisbane /ID# 271836
RECRUITING

South Brisbane, Queensland, 4101, Australia
Moffitt Cancer Center /ID# 272628
RECRUITING

Tampa, Florida, 33612, United States
Mount Sinai - The Tisch Cancer Institute /ID# 272470
RECRUITING

New York, New York, 10029, United States
Nagoya City University Hospital /ID# 273529
RECRUITING

Nagoya, Aichi-ken, 467-8602, Japan
Oncology Hematology Care - Blue Ash /ID# 272918
RECRUITING

Cincinnati, Ohio, 45252, United States
Oslo Universitetssykehus Ulleval /ID# 277915
RECRUITING

Oslo, 0450, Norway
Peter MacCallum Cancer Centre. /ID# 272024
RECRUITING

Melbourne, Victoria, 3000, Australia
Port Macquarie Base Hospital /ID# 275925
RECRUITING

Port Macquarie, New South Wales, 2444, Australia
Rabin Medical Center. /ID# 271365
RECRUITING

Petah Tikva, Central District, 4941492, Israel
Rambam Health Care Campus- Haifa /ID# 271364
RECRUITING

Haifa, 3109601, Israel
Royal Adelaide Hospital /ID# 272629
RECRUITING

Adelaide, South Australia, 5000, Australia
Soroka Medical Center /ID# 271367
RECRUITING

Beersheba, Southern District, 8410101, Israel
St Vincent's Hospital - Melbourne /ID# 276451
RECRUITING

Fitzroy, Victoria, 3065, Australia
The Chaim Sheba Medical Center /ID# 271366
RECRUITING

Ramat Gan, Tel Aviv, 5265601, Israel
The Ohio State University /ID# 271336
RECRUITING

Columbus, Ohio, 43210, United States
The Perth Blood Institute - West Perth /ID# 272469
RECRUITING

West Perth, Western Australia, 6005, Australia
The University of Osaka Hospital /ID# 275791
RECRUITING

Suita-shi, Osaka, 565-0871, Japan
University Hospital Kyoto Prefectural University of Medicine /ID# 275713
RECRUITING

Kyoto, Kyoto, 602-8566, Japan
University Hospital of Wales /ID# 273446
RECRUITING

Cardiff, CF14 4XW, United Kingdom
University Hospitals Birmingham NHS Foundation Trust /ID# 274620
RECRUITING

Birmingham, B15 2TG, United Kingdom
University of North Carolina at Chapel Hill /ID# 274667
RECRUITING

Chapel Hill, North Carolina, 27514, United States
University of Texas - Southwestern Medical Center /ID# 274360
RECRUITING

Dallas, Texas, 75235, United States
Weill Cornell Medical College /ID# 272517
RECRUITING

New York, New York, 10065, United States
Westmead Hospital /ID# 271880
RECRUITING

Westmead, New South Wales, 2145, Australia
Winship Cancer Institute of Emory University /ID# 274830
RECRUITING

Atlanta, Georgia, 30322, United States

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