New drug shows promise for Hard-to-Treat ovarian cancer
NCT ID NCT06682988
First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 27 times
Summary
This study tests a drug called mirvetuximab soravtansine (MIRV) in people with a type of ovarian cancer that no longer responds to platinum chemotherapy. The drug targets a protein called FRα on cancer cells to deliver a cell-killing agent. About 110 participants will receive MIRV on one of two schedules to find the safest and most effective dose, including a group with liver problems. The goal is to control the disease and improve outcomes.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AZ Maria Middelares /ID# 272186
RECRUITINGGhent, Oost-Vlaanderen, 9000, Belgium
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AZ-Delta /ID# 272250
RECRUITINGRoeselare, West-Vlaanderen, 8800, Belgium
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Addenbrookes Hospital /ID# 272162
RECRUITINGCambridge, Cambridgeshire, CB2 2QQ, United Kingdom
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Algemeen Ziekenhuis klina /ID# 272127
RECRUITINGBrasschaat, Antwerpen, 2930, Belgium
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Allegheny Health Network West Penn Hospital /ID# 272267
RECRUITINGPittsburgh, Pennsylvania, 15244, United States
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Asan Medical Center /ID# 272130
RECRUITINGSeoul, Seoul Teugbyeolsi, 05505, South Korea
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Ballarat Base Hospital /ID# 272240
RECRUITINGBallarat, Victoria, 3350, Australia
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Baptist Health Lexington /ID# 272211
RECRUITINGLexington, Kentucky, 40503, United States
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Blacktown Hospital /ID# 272182
RECRUITINGBlacktown, New South Wales, 2148, Australia
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CHA Bundang Medical Center /ID# 271590
RECRUITINGSeongnam, Gyeonggido, 13496, South Korea
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CLINICA UNIVERSIDAD DE NAVARRA-Madrid /ID# 272221
RECRUITINGMadrid, 28027, Spain
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Clinica Universidad de Navarra - Pamplona /ID# 275742
RECRUITINGPamplona, Navarre, 31008, Spain
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First Physicians Group /ID# 272180
RECRUITINGSarasota, Florida, 34239, United States
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Gangnam Severance Hospital /ID# 272217
RECRUITINGSeoul, Seoul Teugbyeolsi, 06273, South Korea
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Hospital Clinico Universitario Lozano Blesa /ID# 272165
RECRUITINGZaragoza, 50009, Spain
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Hospital General Universitario Gregorio Maranon /ID# 272121
RECRUITINGMadrid, 28007, Spain
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Hospital Universitario Germans Trias i Pujol /ID# 272216
RECRUITINGBadalona, Barcelona, 08916, Spain
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Hospital Universitario HM Sanchinarro /ID# 272190
RECRUITINGMadrid, 28050, Spain
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Hospital Universitario Vall de Hebron /ID# 272134
RECRUITINGBarcelona, 08035, Spain
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Hospital Universitario Virgen del Rocio /ID# 272107
RECRUITINGSeville, Sevilla, 41013, Spain
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Hospital Universitario de Jaén /ID# 272205
RECRUITINGJaén, Jaen, 23007, Spain
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Icon Cancer Centre Chermside /ID# 272220
RECRUITINGChermside, Queensland, 4032, Australia
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Karmanos Cancer Institute - Detroit /ID# 272112
RECRUITINGDetroit, Michigan, 48201, United States
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Keimyung University Dongsan Hospital /ID# 271592
RECRUITINGDaegu, Gyeongsangbuk-do, 42601, South Korea
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Monash Health - Monash Medical Centre /ID# 272234
RECRUITINGClayton, Victoria, 3168, Australia
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National Cancer Center /ID# 272265
RECRUITINGGoyang-si, Gyeonggido, 10408, South Korea
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Newcastle Private Hosptial /ID# 272213
RECRUITINGLambton Heights, New South Wales, 2305, Australia
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Royal Brisbane and Women's Hospital /ID# 272123
RECRUITINGBrisbane, Queensland, 4029, Australia
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Royal Devon & Exeter Hospital /ID# 272170
RECRUITINGExeter, Devon, EX2 5DW, United Kingdom
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Samsung Medical Center /ID# 271591
RECRUITINGSeoul, Seoul Teugbyeolsi, 06351, South Korea
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Seoul National University Bundang Hospital /ID# 271594
RECRUITINGSeongnam-si, Gyeonggido, 13620, South Korea
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Seoul National University Hospital /ID# 272264
RECRUITINGSeoul, Seoul Teugbyeolsi, 03080, South Korea
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Sir Charles Gairdner Hospital /ID# 272116
RECRUITINGNedlands, Western Australia, 6009, Australia
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St. Elizabeth Medical Center - Edgewood /ID# 272113
RECRUITINGEdgewood, Kentucky, 41017, United States
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UMass Memorial Medical Center /ID# 272122
RECRUITINGWorcester, Massachusetts, 01605, United States
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University College London Hospital /ID# 272115
RECRUITINGLondon, Greater London, NW1 2BU, United Kingdom
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Yonsei University Health System Severance Hospital /ID# 271593
RECRUITINGSeoul, Seoul Teugbyeolsi, 03722, South Korea
Conditions
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