New hope for Tough-to-Treat blood cancer: experimental drug enters human testing

NCT ID NCT05650632

Recruiting now Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 4 times

Summary

This study tests an experimental drug called etentamig (ABBV-383) in about 210 adults whose multiple myeloma has come back or stopped responding to other treatments. The main goals are to find the best dose and check for side effects. Participants receive the drug as an infusion every 28 days for up to 3 years, with regular monitoring at the clinic.

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Conditions

The condition(s) this trial relates to.

neoplasm plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE MYELOMA

Contacts and locations

Locations

AP-HP - Hopital Saint-Antoine /ID# 252326
COMPLETED

Paris, 75012, France
Atrium Health Wake Forest Baptist Medical Center /ID# 251165
RECRUITING

Winston-Salem, North Carolina, 27157, United States
Baptist Memorial Hospital /ID# 280677
NOT_YET_RECRUITING

Memphis, Tennessee, 38120, United States
CHU Poitiers - La miletrie /ID# 251219
RECRUITING

Poitiers, Vienne, 86000, France
Centre Hospitalier Universitaire de Nantes, Hotel Dieu -HME /ID# 251196
RECRUITING

Nantes, Pays de la Loire Region, 44000, France
Fort Wayne Medical Oncology And Hematology /ID# 268179
RECRUITING

Fort Wayne, Indiana, 46804, United States
Franciscan St. Francis Health /ID# 280928
RECRUITING

Indianapolis, Indiana, 46237, United States
Fred Hutchinson Cancer Center. /ID# 267940
RECRUITING

Seattle, Washington, 98109-4405, United States
HCL - Hopital Lyon Sud /ID# 251223
RECRUITING

Pierre-Bénite, Rhone, 69495, France
Hadassah Medical Center-Hebrew University /ID# 252079
RECRUITING

Jerusalem, Jerusalem, 91120, Israel
Highlands Oncology Group - Springdale /ID# 267742
RECRUITING

Springdale, Arkansas, 72762, United States
Hope And Healing Cancer Services /ID# 268536
RECRUITING

Hinsdale, Illinois, 60521, United States
Hopitaux Universitaires Henri Mondor - Hopital Henri Mondor /ID# 252101
COMPLETED

Créteil, Paris, 94010, France
Hospital Universitario Marques de Valdecilla /ID# 251528
RECRUITING

Santander, Cantabria, 39008, Spain
Hospital Universitario Puerta de Hierro - Majadahonda /ID# 251545
COMPLETED

Majadahonda, Madrid, 28222, Spain
Hospital Universitario de Salamanca /ID# 251529
RECRUITING

Salamanca, 37711, Spain
Institut Paoli-Calmettes /ID# 252100
COMPLETED

Marseille, Bouches-du-Rhone, 13009, France
Juravinski Cancer Centre /ID# 252053
RECRUITING

Hamilton, Ontario, L8V 1C3, Canada
Maryland Oncology Hematology - Silver Spring /ID# 268562
NOT_YET_RECRUITING

Silver Spring, Maryland, 20904, United States
Mayo Clinic - Rochester /ID# 251164
RECRUITING

Rochester, Minnesota, 55905-0001, United States
Mayo Clinic Arizona /ID# 251405
RECRUITING

Phoenix, Arizona, 85054, United States
Medical Oncology Hematology Consultants /ID# 268560
RECRUITING

Newark, Delaware, 19713, United States
Memorial Sloan Kettering Cancer Center-Koch Center /ID# 251167
RECRUITING

New York, New York, 10065-6007, United States
Mt Sinai /ID# 251166
RECRUITING

New York, New York, 10029-6542, United States
NHO Revive Research Institute, LLC /ID# 267869
RECRUITING

Lincoln, Nebraska, 68506, United States
Nebraska Cancer Specialists - Omaha - Wright Street /ID# 282497
RECRUITING

Omaha, Nebraska, 68130, United States
Northwest Medical Specialties Tacoma /ID# 267117
RECRUITING

Tacoma, Washington, 98405, United States
Odense University Hospital /ID# 251261
RECRUITING

Odense, Region Syddanmark, 5000, Denmark
Oncology Consultants /ID# 268323
RECRUITING

Houston, Texas, 77030, United States
Ottawa Hospital Research Institute /ID# 252151
COMPLETED

Ottawa, Ontario, K1H 8L6, Canada
Rabin Medical Center. /ID# 251330
RECRUITING

Petah Tikva, Central District, 4941492, Israel
Rocky Mountain Cancer Centers - Aurora /ID# 268574
RECRUITING

Aurora, Colorado, 80012, United States
Tel Aviv Sourasky Medical Center /ID# 251573
RECRUITING

Tel Aviv, Tel Aviv, 6423906, Israel
Texas Oncology - Central/South Texas /ID# 268563
RECRUITING

Austin, Texas, 78705, United States
Texas Oncology - Dallas - Worth Street /ID# 280064
RECRUITING

Dallas, Texas, 75246, United States
Texas Oncology - Northeast Texas /ID# 268877
RECRUITING

Tyler, Texas, 75702, United States
The Chaim Sheba Medical Center /ID# 251329
RECRUITING

Ramat Gan, Tel Aviv, 5265601, Israel
The Christie Hospital /ID# 251774
RECRUITING

Manchester, M20 4BX, United Kingdom
Tulane University School of Medicine /ID# 251204
RECRUITING

New Orleans, Louisiana, 70112, United States
University College London Hospital /ID# 251357
RECRUITING

London, Greater London, NW1 2BU, United Kingdom
University Of Cincinnati Medical Center /ID# 251746
RECRUITING

Cincinnati, Ohio, 45219, United States
University of North Carolina /ID# 251203
RECRUITING

Chapel Hill, North Carolina, 27514, United States
Vanderbilt Ingram Cancer Center /ID# 252470
RECRUITING

Nashville, Tennessee, 37232-0021, United States
Vejle Sygehus /ID# 251260
RECRUITING

Vejle, Region Syddanmark, 7100, Denmark
Virginia Cancer Specialists - Fairfax /ID# 268559
RECRUITING

Fairfax, Virginia, 22031, United States
Willamette Valley Cancer Institute and Research Center /ID# 267088
RECRUITING

Eugene, Oregon, 97401, United States

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