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New hope for lung cancer patients whose current meds stop working

NCT ID NCT07155187

Recruiting now Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 34 times

Summary

This study tests an experimental drug, telisotuzumab adizutecan, against standard care in about 430 adults with a specific type of advanced lung cancer (EGFR-mutated non-squamous non-small cell lung cancer) that has worsened after using a third-generation targeted therapy. The goal is to see if the new drug can shrink tumors or delay cancer growth better than current options. Participants will receive either one of two doses of the experimental drug or standard treatment, and will be monitored for side effects and disease changes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center /ID# 277371

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 05505, South Korea

  • Astera Cancer Care /ID# 277570

    RECRUITING

    East Brunswick, New Jersey, 08816-4096, United States

  • Canberra Hospital /ID# 277166

    RECRUITING

    Garran, Australian Capital Territory, 2605, Australia

  • Cancer Care Centers of Brevard- Rockledge /ID# 277853

    RECRUITING

    Rockledge, Florida, 32955, United States

  • Changhua Christian Hospital /ID# 277145

    RECRUITING

    Changhua, 500, Taiwan

  • Chungbuk National University Hospital /ID# 277372

    RECRUITING

    Cheongju-si, North Chungcheong, 28644, South Korea

  • Guangdong Provincial People'S Hospital /ID# 277631

    RECRUITING

    Guangzhou, Guangdong, 510080, China

  • HealthPartners Cancer Research Center /ID# 277339

    RECRUITING

    Saint Louis Park, Minnesota, 55426, United States

  • Highlands Oncology Group - Springdale /ID# 277132

    RECRUITING

    Springdale, Arkansas, 72762, United States

    Contact Phone: •••-•••-••••

  • Hokkaido University Hospital /ID# 277240

    RECRUITING

    Sapporo, Hokkaido, 060-8648, Japan

  • Hospital Clinico Universitario Lozano Blesa /ID# 277154

    RECRUITING

    Zaragoza, 50009, Spain

  • Hospital Clinico Universitario de Valencia /ID# 277147

    RECRUITING

    Valencia, 46010, Spain

  • Hospital Universitario Virgen de la Victoria /ID# 277159

    RECRUITING

    Málaga, 29010, Spain

  • Icon Cancer Centre Hobart /ID# 277549

    RECRUITING

    Hobart, Tasmania, 7000, Australia

  • Istituto di Candiolo Fondazione del Piemonte per l'Oncologia IRCCS /ID# 277119

    RECRUITING

    Candiolo, Torino, 10060, Italy

  • Jessa Ziekenhuis - Campus Virga Jesse /ID# 277202

    RECRUITING

    Hasselt, Limburg, 3500, Belgium

  • Kaohsiung Medical University Chung-Ho Memorial Hospital /ID# 277138

    RECRUITING

    Kaohsiung City, 807, Taiwan

  • Kitasato University Hospital /ID# 277241

    RECRUITING

    Sagamihara-shi, Kanagawa, 252-0375, Japan

  • Klinik Floridsdorf /ID# 276679

    RECRUITING

    Vienna, State of Vienna, 1210, Austria

  • Mackay Memorial Hospital /ID# 277146

    RECRUITING

    Taipei, 104, Taiwan

  • Mater Hospital Brisbane /ID# 276985

    RECRUITING

    South Brisbane, Queensland, 4101, Australia

  • Meir Medical Center /ID# 277289

    RECRUITING

    Kfar Saba, Central District, 4428164, Israel

  • National Cancer Center /ID# 277353

    RECRUITING

    Goyang-si, Gyeonggido, 10408, South Korea

  • National Cancer Center Hospital /ID# 277093

    RECRUITING

    Chuo-Ku, Tokyo, 104-0045, Japan

  • Nho - Revive Research Institute /ID# 277569

    RECRUITING

    Lincoln, Nebraska, 68506, United States

  • Northwest Cancer Specialists - Vancouver /ID# 277855

    RECRUITING

    Vancouver, Washington, 98684, United States

  • One Clinical Research - Nedlands /ID# 277598

    RECRUITING

    Nedlands, Western Australia, 6009, Australia

  • Ospedale Isola Tiberina - Gemelli Isola /ID# 277117

    RECRUITING

    Rome, Roma, 00186, Italy

  • Rabin Medical Center /ID# 276748

    RECRUITING

    Petah Tikva, Central District, 4941492, Israel

  • Rambam Health Care Campus- Haifa /ID# 276746

    RECRUITING

    Haifa, 3525408, Israel

  • SCRI Oncology Partners /ID# 276959

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Samsung Medical Center /ID# 277600

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 06351, South Korea

  • Seoul National University Hospital /ID# 277373

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 03080, South Korea

  • St George Hospital /ID# 277168

    RECRUITING

    Kogarah, New South Wales, 2217, Australia

  • St Vincent's Hospital Melbourne /ID# 277002

    RECRUITING

    Fitzroy, Victoria, 03065, Australia

  • Sunshine Hospital /ID# 276894

    RECRUITING

    St Albans, Victoria, 3021, Australia

  • Taichung Veterans General Hospital /ID# 277142

    RECRUITING

    Taichung, 407, Taiwan

  • Taipei Veterans General Hospital /ID# 277141

    RECRUITING

    Taipei, 112, Taiwan

  • Tennessee Cancer Specialists - Knoxville - Old Weisgarber Road /ID# 277891

    RECRUITING

    Knoxville, Tennessee, 37909, United States

  • The Chaim Sheba Medical Center /ID# 276745

    RECRUITING

    Ramat Gan, Tel Aviv, 5265601, Israel

  • Unidade Local de Saude de Braga, EPE /ID# 277217

    RECRUITING

    Braga, 4710-243, Portugal

  • Unidade Local de Saude de Loures-Odivelas, EPE /ID# 277223

    RECRUITING

    Loures, Lisbon District, 2674-514, Portugal

  • Unidade Local de Saude de Matosinhos, EPE /ID# 277228

    RECRUITING

    Senhora da Hora, Porto District, 4464-513, Portugal

  • Unidade Local de Saude de Santo Antonio, E.P.E. /ID# 277216

    RECRUITING

    Porto, 4099-003, Portugal

  • Unidade Local de Saude do Alto Ave, EPE /ID# 277249

    RECRUITING

    Guimarães, Braga District, 4835-044, Portugal

  • Universitaetsklinikum Giessen und Marburg GmbH /ID# 276873

    RECRUITING

    Marburg, Hesse, 35043, Germany

  • Universitaetsklinikum Heidelberg /ID# 277275

    RECRUITING

    Heidelberg, Baden-Wurttemberg, 69120, Germany

  • Universitaetsklinikum Koeln /ID# 276862

    RECRUITING

    Cologne, North Rhine-Westphalia, 50937, Germany

  • Universitaetsklinikum Wuerzburg /ID# 277213

    RECRUITING

    Würzburg, Bavaria, 97080, Germany

  • Universitair Ziekenhuis Leuven /ID# 276874

    RECRUITING

    Leuven, Vlaams-Brabant, 3000, Belgium

  • Universitätsklinikum Jena /ID# 277281

    RECRUITING

    Jena, Thuringia, 07747, Germany

  • Wakayama Medical University Hospital /ID# 277238

    RECRUITING

    Wakayama, Wakayama, 641-8510, Japan

  • Yitzhak Shamir Medical Center /ID# 276750

    RECRUITING

    Ẕerifin, Central District, 7030000, Israel

Conditions

Explore the condition pages connected to this study.

NON-SMALL CELL LUNG CANCER