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New drug combo aims to fight aggressive lung cancer

NCT ID NCT07155174

Recruiting now Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 01, 2026 · Updated 4 times

Summary

This study tests a new drug called ABBV-706 combined with the immunotherapy atezolizumab as a first treatment for people with extensive-stage small cell lung cancer, a fast-growing cancer that has spread. About 180 adults will receive either the new combination at one of two doses or standard chemotherapy plus immunotherapy. Researchers will check safety and how long the cancer stays under control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ABBV-706 (an investigational drug) combined with atezolizumab (an immunotherapy)

What this could lead to

If successful, this could offer a new first-line treatment option for extensive-stage small cell lung cancer, potentially improving how long patients live without their cancer growing.

What could go wrong

This is an early Phase 2 study with only 180 participants, so results may not apply to everyone. The new combination may cause more side effects than standard care, and it is not yet proven to be better.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SMALL CELL LUNG CANCER

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AZ Maria Middelares /ID# 277027

    RECRUITING

    Ghent, Oost-Vlaanderen, 9000, Belgium

  • Ankara Universitesi Tip Fakultesi Cebeci Hastanesi /ID# 277076

    RECRUITING

    Ankara, 06620, Turkey (Türkiye)

  • Asan Medical Center /ID# 277603

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 05505, South Korea

  • Assuta Ashdod Medical Center /ID# 276661

    RECRUITING

    Ashdod, Southern District, 7747600, Israel

  • Baptist Health Lexington /ID# 277729

    RECRUITING

    Lexington, Kentucky, 40503, United States

  • Cancer Hospital - Chinese Academy of Medical Sciences /ID# 277167

    RECRUITING

    Beijing, Beijing Municipality, 100021, China

  • Chung Shan Medical University Hospital /ID# 277660

    RECRUITING

    Taichung, 402, Taiwan

  • Chungbuk National University Hospital /ID# 277429

    RECRUITING

    Cheongju-si, North Chungcheong, 28644, South Korea

  • Clinical Hospital Center - Bežanijska Kosa /ID# 277013

    RECRUITING

    Belgrade, Beograd, 11080, Serbia

  • Complejo Hospitalario Universitario A Coruña /ID# 276922

    RECRUITING

    A Coruña, A Coruna, 15006, Spain

  • Dana-Farber Cancer Institute /ID# 277732

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Evangelische Lungenklinik Berlin /ID# 277094

    RECRUITING

    Berlin, 13125, Germany

  • Fort Wayne Medical Oncology And Hematology /ID# 277336

    RECRUITING

    Fort Wayne, Indiana, 46804, United States

  • Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi /ID# 276839

    RECRUITING

    Istanbul, 34722, Turkey (Türkiye)

  • Grand Hopital de Charleroi - Les Viviers /ID# 276897

    RECRUITING

    Charleroi, Hainaut, 6280, Belgium

  • Groupe Sante CHC - Clinique du MontLegia /ID# 276783

    RECRUITING

    Liège, Liege, 4000, Belgium

  • Hadassah Medical Center-Hebrew University /ID# 276662

    RECRUITING

    Jerusalem, 91120, Israel

  • Hospital Clinic de Barcelona /ID# 276878

    RECRUITING

    Barcelona, 08036, Spain

  • Hospital Regional Universitario de Malaga /ID# 276927

    RECRUITING

    Málaga, Andalusia, 29010, Spain

  • Hospital Universitario 12 de Octubre /ID# 277251

    RECRUITING

    Madrid, 28041, Spain

  • Institute For Pulmonary Diseases Of Vojvodina /ID# 277003

    RECRUITING

    Kamenitz, Sremski Okrug, 21208, Serbia

  • Jessa Ziekenhuis - Campus Virga Jesse /ID# 276781

    RECRUITING

    Hasselt, Limburg, 3500, Belgium

  • Kaohsiung Chang Gung Memorial Hospital /ID# 277725

    RECRUITING

    Kaohsiung City, 833, Taiwan

  • Kaohsiung Medical University Chung-Ho Memorial Hospital /ID# 277267

    RECRUITING

    Kaohsiung City, 807, Taiwan

  • Linkou Chang Gung Memorial Hospital /ID# 277264

    RECRUITING

    Taoyuan City, 333, Taiwan

  • Lungenfachklinik Immenhausen /ID# 278005

    RECRUITING

    Immenhausen, Hesse, 34376, Germany

    Contact Phone: •••-•••-••••

  • Meir Medical Center /ID# 277292

    RECRUITING

    Kefar Sava, Central District, 4428164, Israel

  • Missouri Cancer Associates /ID# 278299

    RECRUITING

    Columbia, Missouri, 65201, United States

  • Moffitt Cancer Center /ID# 277573

    RECRUITING

    Tampa, Florida, 33612, United States

  • Narodowy Instytut Onkologii Im. Marii Sklodowskiej-Curie Panstwowy Instytut Bada /ID# 277112

    RECRUITING

    Warsaw, Masovian Voivodeship, 02-781, Poland

  • National Cancer Center /ID# 277434

    RECRUITING

    Goyang-si, Gyeonggido, 10408, South Korea

  • National Cancer Center Hospital /ID# 277237

    RECRUITING

    Chuo-Ku, Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East /ID# 277239

    RECRUITING

    Kashiwa-shi, Chiba, 277-8577, Japan

  • Ocala Oncology Center /ID# 278269

    RECRUITING

    Ocala, Florida, 34474, United States

  • Rambam Health Care Campus- Haifa /ID# 276663

    RECRUITING

    Haifa, 3109601, Israel

  • Samsung Medical Center /ID# 277615

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 06351, South Korea

  • Seoul National University Hospital /ID# 277271

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 03080, South Korea

  • Shanghai East Hospital /ID# 277111

    RECRUITING

    Shanghai, Shanghai Municipality, 200120, China

  • Shizuoka Cancer Center /ID# 277243

    RECRUITING

    Sunto-gun, Shizuoka, 411-8777, Japan

  • Taipei Veterans General Hospital /ID# 277263

    RECRUITING

    Taipei, 112, Taiwan

  • The Chaim Sheba Medical Center /ID# 276660

    RECRUITING

    Ramat Gan, Tel Aviv, 5265601, Israel

  • The First affiliated hospital of Nanchang University - Nanchang /ID# 277247

    RECRUITING

    Nanchang, Jiangxi, 330006, China

  • The University of Texas MD Anderson Cancer Center /ID# 277929

    RECRUITING

    Houston, Texas, 77030, United States

  • Tokyo Metropolitan Komagome Hospital /ID# 277335

    RECRUITING

    Bunkyo Ku, Tokyo, 113-8677, Japan

  • Universitaetsklinikum Giessen und Marburg GmbH /ID# 277466

    RECRUITING

    Marburg, Hesse, 35043, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Clinical Center Kragujevac /ID# 277179

    RECRUITING

    Kragujevac, Sumadijski Okrug, 34000, Serbia

  • University Clinical Center Nis /ID# 277180

    RECRUITING

    Niš, Nisavski Okrug, 18300, Serbia

  • University Clinical Center Serbia /ID# 277007

    RECRUITING

    Belgrade, Beograd, 11000, Serbia

  • University Hospitals Cleveland Medical Center /ID# 277556

    RECRUITING

    Cleveland, Ohio, 44106, United States

  • Uniwersytecki Szpital Kliniczny Nr 4 w Lublinie /ID# 276910

    RECRUITING

    Lublin, Lublin Voivodeship, 20-090, Poland

  • Virginia Cancer Specialists - Fairfax /ID# 278298

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • Wakayama Medical University Hospital /ID# 277260

    RECRUITING

    Wakayama, Wakayama, 641-8510, Japan

  • Wielkopolskie Centrum Pulmonologii i Torakochirurgii im. Eugenii i Janusza Zeyla /ID# 276907

    RECRUITING

    Poznan, Greater Poland Voivodeship, 60-569, Poland

  • Yale University School of Medicine /ID# 278181

    RECRUITING

    New Haven, Connecticut, 06510, United States

  • Yonsei University Health System Severance Hospital /ID# 277597

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 03722, South Korea