New gel stent could help glaucoma patients see clearly

NCT ID NCT06822738

Recruiting now Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 3 times

Summary

This study tests a gel stent implant designed to lower eye pressure in people with glaucoma. About 130 adults aged 45 and older will receive the stent through one of two surgical methods. Researchers will check safety and how well the stent reduces eye pressure over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: gel stent (XEN63)
What this could lead to: If successful, this could offer a new surgical option to lower eye pressure in glaucoma patients who haven't responded to other treatments.
What could go wrong: This is a Phase 3 trial, but the device is still investigational. Results may not apply to all glaucoma types, and risks include surgical complications or the stent not working as expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

open-angle glaucoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PRIMARY OPEN ANGLE GLAUCOMA

Contacts and locations

Locations

Arizona Advanced Eye Research Institute /ID# 268363
RECRUITING

Glendale, Arizona, 85306, United States
Berkeley Eye Center - Houston Greenway Plaza /ID# 277078
RECRUITING

Houston, Texas, 77027, United States
Brandon Eye Associates - Brandon /ID# 277074
RECRUITING

Brandon, Florida, 33511, United States
Cincinnati Eye Institute /ID# 279773
RECRUITING

Cincinnati, Ohio, 45242, United States
Cleveland Clinic - Cleveland /ID# 277070
RECRUITING

Cleveland, Ohio, 44195, United States
Coastal Research Associates - Roswell /ID# 268458
RECRUITING

Roswell, Georgia, 30076, United States
Colorado Eye Institute /ID# 277072
RECRUITING

Colorado Springs, Colorado, 80924, United States
East Coast Institute for Research /ID# 280411
RECRUITING

Jacksonville, Florida, 32256, United States
El Paso Eye Surgeons /ID# 268356
RECRUITING

El Paso, Texas, 79902, United States
Eye Center of Northern Colorado /ID# 281798
NOT_YET_RECRUITING

Fort Collins, Colorado, 80528, United States
Fraser Eye Care Center /ID# 281837
RECRUITING

Fraser, Michigan, 48026, United States
Glaucoma Associates Of Texas /ID# 268745
RECRUITING

Dallas, Texas, 75231, United States
Illinois Eye Center - Peoria Location /ID# 277127
RECRUITING

Peoria, Illinois, 61615, United States
LA Glaucoma Group /ID# 268444
RECRUITING

Culver City, California, 90232, United States
Minnesota Eye Consultants - Minneapolis /ID# 272445
RECRUITING

Minneapolis, Minnesota, 55431, United States
New Vision Eye Center /ID# 269955
RECRUITING

Vero Beach, Florida, 32960, United States
North Bay Eye Associates /ID# 277071
RECRUITING

Petaluma, California, 94954, United States
Oklahoma Eye Surgeons /ID# 269174
RECRUITING

Oklahoma City, Oklahoma, 73112, United States
Ophthalmic Partners of PA /ID# 276059
RECRUITING

Bala-Cynwyd, Pennsylvania, 19004, United States
Stiles Eyecare Excellence & Glaucoma Institute /ID# 268451
COMPLETED

Overland Park, Kansas, 66213, United States
The Eye Centers of Racine and Kenosha /ID# 271266
RECRUITING

Kenosha, Wisconsin, 53142, United States
Tulane Center for Clinical Research /ID# 277486
RECRUITING

New Orleans, Louisiana, 70112-2703, United States
University Of Colorado - Anschutz Medical Campus /ID# 269947
RECRUITING

Aurora, Colorado, 80045, United States
University of Texas - Southwestern Medical Center /ID# 268571
RECRUITING

Dallas, Texas, 75235, United States
University of Virginia /ID# 277487
RECRUITING

Charlottesville, Virginia, 22908, United States
Vance Thompson Vision - Omaha /ID# 271599
RECRUITING

Omaha, Nebraska, 68137, United States
Vistar Eye Center - Roanoke - South Jefferson Street /ID# 276119
COMPLETED

Roanoke, Virginia, 24016, United States
Wills Eye Hospital /ID# 268569
RECRUITING

Philadelphia, Pennsylvania, 19107, United States

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