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New hope for myeloma patients who Can't have transplants

NCT ID NCT07095452

Recruiting now Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental drug called etentamig combined with daratumumab in people newly diagnosed with multiple myeloma who are not eligible for a stem cell transplant. About 660 participants will receive either the new combination or standard treatment. The goal is to see if the new combo improves response rates and delays disease progression.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Etentamig (an investigational drug) combined with daratumumab

What this could lead to

If successful, this could offer a new treatment option for people with newly diagnosed multiple myeloma who cannot have a stem cell transplant, potentially improving disease control and survival.

What could go wrong

This is an early-to-mid-stage trial, so the experimental drug may not work better than current treatments or could cause unexpected side effects. Results may take years to confirm.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE MYELOMA

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Blue Ridge Cancer Care - Roanoke /ID# 278722

    RECRUITING

    Roanoke, Virginia, 24014, United States

  • CH Bretagne Atlantique /ID# 278422

    RECRUITING

    Vannes, Morbihan, 56000, France

  • CHRU Tours - Hopital Bretonneau /ID# 279274

    RECRUITING

    Tours, Indre-et-Loire, 37044, France

  • CHU de Montpellier - Hopital Saint Eloi /ID# 278415

    RECRUITING

    Montpellier, Herault, 34295, France

  • Cedars-Sinai Medical Center /ID# 278238

    RECRUITING

    Los Angeles, California, 90048, United States

  • Centre Hospitalier Annecy Genevois /ID# 278406

    RECRUITING

    Epagny Metz Tessy, Auvergne-Rhône-Alpes, 74370, France

  • Centre Hospitalier De Dunkerque-Hospital Alexandra Lepeve /ID# 278399

    RECRUITING

    Dunkirk, Hauts-de-France, 59385, France

  • Centre Hospitalier Universitaire de Bordeaux /ID# 278419

    RECRUITING

    Pessac, New Aquitaine, 33604, France

  • Centre Hospitalier Universitaire de Nantes, Hotel Dieu -HME /ID# 278402

    RECRUITING

    Nantes, Pays de la Loire Region, 44000, France

  • Centre Hospitalier Universitaire de Poitiers /ID# 278398

    RECRUITING

    Poitiers, New Aquitaine, 86021, France

  • Centre Hospitalier Universitaire de Saint Etienne - Hopital Nord /ID# 278421

    RECRUITING

    St-Priest-en-Jarez, Pays de la Loire Region, 42270, France

  • Chu De Lille - Hopital Claude Huriez /ID# 278413

    RECRUITING

    Lille, Hauts-de-France, 59037, France

  • Clinica Universidad de Navarra - Pamplona /ID# 278583

    RECRUITING

    Pamplona, Navarre, 31008, Spain

  • Colorado Blood Cancer Institute /ID# 279080

    RECRUITING

    Denver, Colorado, 80218, United States

  • Complejo Asistencial Universitario de Leon - Hospital de Leon /ID# 278534

    RECRUITING

    León, 24071, Spain

  • Complejo Hospitalario Universitario de Santiago /ID# 278531

    RECRUITING

    Santiago de Compostela, A Coruna, 15706, Spain

  • Fort Wayne Medical Oncology And Hematology /ID# 278141

    RECRUITING

    Fort Wayne, Indiana, 46804, United States

  • HCL - Hopital Lyon Sud /ID# 282145

    RECRUITING

    Pierre-Bénite, Rhone, 69495, France

  • Hopital Saint Antoine /ID# 278428

    RECRUITING

    Paris, 75012, France

  • Hopital Saint-Louis /ID# 278429

    RECRUITING

    Paris, 75010, France

  • Hopital Universitaire Necker Enfants Malades /ID# 278426

    RECRUITING

    Paris, Île-de-France Region, 75015, France

  • Hospital Clinic de Barcelona /ID# 278532

    RECRUITING

    Barcelona, 08036, Spain

  • Hospital General Universitario Gregorio Maranon /ID# 278551

    RECRUITING

    Madrid, 28007, Spain

  • Hospital Universitari i Politecnic La Fe /ID# 278525

    RECRUITING

    Valencia, 46026, Spain

  • Hospital Universitario 12 de Octubre /ID# 278520

    RECRUITING

    Madrid, 28041, Spain

  • Hospital Universitario Marques de Valdecilla /ID# 278535

    RECRUITING

    Santander, Cantabria, 39008, Spain

  • Hospital Universitario Ramon y Cajal /ID# 278533

    RECRUITING

    Madrid, 28034, Spain

  • Hospital Universitario de Gran Canaria Doctor Negrín /ID# 278527

    RECRUITING

    Las Palmas de Gran Canaria, Las Palmas, 35010, Spain

  • Hospital Universitario de Salamanca /ID# 278530

    RECRUITING

    Salamanca, 37007, Spain

  • IUCT Oncopole /ID# 278403

    RECRUITING

    Toulouse, Occitanie, 31059, France

  • Icahn School of Medicine at Mount Sinai /ID# 277844

    RECRUITING

    New York, New York, 10029, United States

  • Institut Catala d'Oncologia (ICO) - Badalona /ID# 278522

    RECRUITING

    Badalona, Barcelona, 08916, Spain

  • Kurume University Hospital /ID# 278209

    RECRUITING

    Kurume-shi, Fukuoka, 830-0011, Japan

  • Matsuyama Red Cross Hospital /ID# 278660

    RECRUITING

    Matsuyama, Ehime, 790-8524, Japan

  • Mayo Clinic Hospital Rochester /ID# 277886

    RECRUITING

    Rochester, Minnesota, 55905, United States

  • Mayo Clinic Hospital Scottsdale /ID# 278349

    RECRUITING

    Scottsdale, Arizona, 85259, United States

  • Memorial Sloan Kettering Cancer Center - New York - York Avenue /ID# 277946

    RECRUITING

    New York, New York, 10065, United States

  • Minnesota Oncology - Minneapolis Clinic /ID# 278720

    RECRUITING

    Minneapolis, Minnesota, 55404, United States

  • Nagoya City University Hospital /ID# 278188

    RECRUITING

    Nagoya, Aichi-ken, 467-8602, Japan

  • SCRI Oncology Partners /ID# 278353

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Texas Oncology - Northeast Texas /ID# 278725

    RECRUITING

    Tyler, Texas, 75702, United States

  • Texas Oncology - The Woodlands /ID# 278726

    RECRUITING

    The Woodlands, Texas, 77380, United States

  • Tokai University Hospital /ID# 278157

    RECRUITING

    Isehara, Kanagawa, 259-1193, Japan

  • University Hospital Kyoto Prefectural University of Medicine /ID# 278156

    RECRUITING

    Kyoto, Kyoto, 602-8566, Japan

  • University of North Carolina at Chapel Hill /ID# 277708

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

  • Virginia Cancer Specialists - Fairfax /ID# 278716

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • Weill Cornell Medicine Myeloma Center /ID# 278216

    RECRUITING

    New York, New York, 10065, United States

  • Willamette Valley Cancer Institute and Research Center /ID# 278721

    RECRUITING

    Eugene, Oregon, 97401, United States

  • Winship Cancer Institute of Emory University /ID# 277667

    RECRUITING

    Atlanta, Georgia, 30322, United States