New pill could ease bipolar depression – trial underway

NCT ID NCT06696755

Recruiting now Symptom relief Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 3 times

Summary

This study tests an experimental drug called icalcaprant for treating depression in people with bipolar I or II disorder. About 195 adults will take either the drug or a placebo daily for 6 weeks. Researchers will measure changes in depression symptoms and watch for side effects.

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Conditions

The condition(s) this trial relates to.

bipolar disorder bipolar I disorder bipolar II disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BIPOLAR I DISORDER BIPOLAR II DISORDER

Contacts and locations

Locations

Accel Research Sites Network - St. Pete /ID# 272962
RECRUITING

Largo, Florida, 33777, United States
Advanced Research Center /ID# 272828
RECRUITING

Anaheim, California, 92805, United States
Amr Conventions Research /ID# 272867
RECRUITING

Warrenville, Illinois, 60555, United States
Apg Research /ID# 272925
RECRUITING

Orlando, Florida, 32803, United States
Catalina Research Institute /ID# 272831
RECRUITING

Montclair, California, 91763, United States
CenExel Hollywood FL /ID# 273101
RECRUITING

Hollywood, Florida, 33024, United States
Chandler Clinical Research Trials /ID# 274500
RECRUITING

Chandler, Arizona, 85224, United States
Clinical Research Center Of Florida /ID# 278790
RECRUITING

Pompano Beach, Florida, 33060, United States
Collaborative Neuroscience Research - Garden Grove /ID# 271917
RECRUITING

Garden Grove, California, 92845, United States
Combined Research Orlando /ID# 279458
RECRUITING

Orlando, Florida, 32814, United States
Community Clinical Research - Cross Park Drive /ID# 272940
RECRUITING

Austin, Texas, 78754, United States
Core Clinical Research /ID# 272955
RECRUITING

Everett, Washington, 98201, United States
Del Sol Research Management - East Tanque Verde Road - Tucson /ID# 279767
RECRUITING

Tucson, Arizona, 85715, United States
Elixia - Houston /ID# 279200
RECRUITING

Houston, Texas, 77007, United States
Excell Research /ID# 272854
RECRUITING

Oceanside, California, 92056, United States
Family Psychiatry Of The Woodlands /ID# 275177
RECRUITING

The Woodlands, Texas, 77381, United States
Georgia Psychiatric Consultants and Advanced Discovery Research /ID# 279438
RECRUITING

Atlanta, Georgia, 30318, United States
Manhattan Behavioral Medicine /ID# 279769
RECRUITING

New York, New York, 10036, United States
Mind Matters Psychiatry /ID# 273536
RECRUITING

Missouri City, Texas, 77459-5204, United States
Neuroscience Institute - West Palm Beach /ID# 272922
RECRUITING

West Palm Beach, Florida, 33407, United States
Northwest Clinical Research Center /ID# 272847
RECRUITING

Bellevue, Washington, 98007, United States
Pacific Neuropsychiatric Specialists - Orange /ID# 273118
RECRUITING

Orange, California, 92868, United States
Pillar Clinical Research - Chicago /ID# 272823
RECRUITING

Chicago, Illinois, 60641, United States
Pillar Clinical Research - Richardson /ID# 272821
RECRUITING

Richardson, Texas, 75080, United States
Saint Charles Psychiatric Associates /ID# 279239
RECRUITING

Saint Charles, Missouri, 63304, United States
Sanro Clinical Research Group /ID# 279462
RECRUITING

Bryant, Arkansas, 72022, United States
Sarkis Clinical Trials- Gainesville /ID# 272861
RECRUITING

Gainesville, Florida, 32607, United States
Schuster Medical Research Institute /ID# 272848
RECRUITING

Sherman Oaks, California, 91403, United States
Sooner Clinical Research /ID# 272856
RECRUITING

Oklahoma City, Oklahoma, 73116, United States
St. Johns Center for Clinical Research - Saint Augustine Location /ID# 279465
RECRUITING

Saint Augustine, Florida, 32086, United States
The Ohio State University /ID# 272954
RECRUITING

Columbus, Ohio, 43210, United States
University Of Cincinnati Medical Center /ID# 274160
RECRUITING

Cincinnati, Ohio, 45219, United States
University of Alabama - Huntsville Regional Medical Campus /ID# 272951
RECRUITING

Huntsville, Alabama, 35801, United States

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