Cord blood transplants: a new hope for Hard-to-Treat blood diseases?
NCT ID NCT03016806
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing whether umbilical cord blood stem cells from unrelated donors can safely and effectively restore blood cell production in people with serious conditions like leukemia, immune deficiencies, and inherited blood disorders. The main goal is to see how quickly the new cells start working (engraftment) and how often the transplant fails. Researchers are also tracking side effects like graft-versus-host disease, where donor cells attack the patient's body.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- umbilical cord blood stem cells
- What this could lead to
- If successful, this could improve the success rate of cord blood transplants for people with serious blood or immune disorders, offering a potential path to disease control.
- What could go wrong
- This is a small, early-phase study (30 participants) focused on feasibility and safety. The transplant may fail to engraft, or patients may develop severe graft-versus-host disease, a serious complication.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Wilmot Cancer Institute
RECRUITINGRochester, New York, 14642, United States
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