Gene-Matching trial aims to outsmart cancer by pairing mutations with drugs

NCT ID NCT02534649

Recruiting now Knowledge-focused Sponsor: Institut Bergonié Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is analyzing tumor and blood samples from 10,000 adults with advanced solid tumors or blood cancers to find genetic changes that can be targeted by existing drugs. The goal is to see how often these 'actionable' alterations occur and to guide patients toward personalized treatment options. No new drugs are being tested; instead, the focus is on gathering information to improve future treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors select more effective, personalized treatments for advanced cancer patients based on their tumor's genetic profile.
What could go wrong: This is an observational profiling study, not a treatment trial. It may not directly improve outcomes, and many patients may not have a targetable alteration.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hematopoietic and lymphoid system neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEMATOLOGICAL MALIGNANCY SOLID TUMOR

Contacts and locations

Locations

Centre Eugène Marquis
ACTIVE_NOT_RECRUITING

Rennes, France
Centre Hospitalier de Pau
NOT_YET_RECRUITING

Pau, 64000, France
Centre Hospitalier de la Côte Basque
RECRUITING

Bayonne, 64000, France
Clinique Marzet
RECRUITING

Pau, 64000, France
Clinique Tivoli-Ducos
RECRUITING

Bordeaux, 33000, France
Institut Bergonie
RECRUITING

Bordeaux, 33076, France
Polyclinique Bordeaux Nord Aquitaine
RECRUITING

Bordeaux, 33077, France

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