New drug targets tough cancers in early trial

NCT ID NCT06616766

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called YH42946 in people with advanced solid tumors that have certain gene changes (HER2 or EGFR). The main goals are to check safety and see if the drug shrinks tumors. About 161 adults who have run out of standard options will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center, University of Ulsan

    RECRUITING

    Seoul, South Korea

    Contact

    Contact

  • Chungbuk National University Hospital

    RECRUITING

    Cheongju-si, North Chungcheong, 28644, South Korea

    Contact

    Contact

  • Next Oncology Virginia

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact

  • Samsung Medical Center

    RECRUITING

    Seoul, 06351, South Korea

    Contact

  • Seoul National University Bundang Hospital

    RECRUITING

    Seongnam-si, Gyeonggi-do, 13620, South Korea

    Contact

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

    Contact

  • Severance Hospital, Yonsei University

    RECRUITING

    Seoul, 03722, South Korea

    Contact

  • The Catholic Univ. of Korea St. Vincent's Hospital

    RECRUITING

    Suwon, Gyeonggi-do, 16247, South Korea

    Contact