New combo aims to revive immunotherapy in stubborn tumors
NCT ID NCT07404332
First seen Feb 16, 2026 · Last updated May 14, 2026 · Updated 12 times
Summary
This early-phase study tests whether adding a drug called 5-Azacitidine can help standard immunotherapies work again in people with advanced solid tumors that no longer respond to PD-1 or PD-L1 inhibitors. About 35 adults with certain types of cancer will receive the combination to find the safest and most effective dose. The goal is to control the disease, not to cure it, as ongoing treatment is expected.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Iowa Health Care
Iowa City, Iowa, 52242, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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