Could a common supplement supercharge cancer immunotherapy?

NCT ID NCT07161310

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether urolithin A, a dietary supplement, can improve the immune system's response to standard immunotherapy drugs in people with newly diagnosed solid tumors like lung cancer or melanoma. 45 participants will be randomly assigned to receive either urolithin A or a placebo alongside their first-line immunotherapy. The main goal is to see if the supplement changes the types of immune cells in the blood.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Urolithin A (a dietary supplement)

What this could lead to

If it works, this could point toward a way to enhance the effectiveness of immunotherapy for solid tumors like lung cancer and melanoma.

What could go wrong

This is a very early, small trial (45 people) focused on immune system changes, not on curing cancer. The supplement may have no effect or could interact with treatments in unexpected ways.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer melanoma neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Universitätsklinikum Frankfurt, Medizinische Klinik II, Hämatologie/Onkologie

    RECRUITING

    Frankfurt, 60590, Germany

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact