New pill targets rare gene fusion in Hard-to-Treat cancers

NCT ID NCT06010342

First seen Apr 28, 2026 · Last updated Apr 28, 2026

Summary

This study tests a new drug called TL118 for people with advanced solid tumors that have a specific gene change (NTRK fusion). The goal is to see if the drug can shrink tumors or slow their growth. About 60 adults whose cancer has worsened after other treatments will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Adventist Health Glendale

    RECRUITING

    Glendale, California, 91206, United States

  • Affiliated Cancer Hospital and Institute of Guangzhou Medical University

    RECRUITING

    Guangzhou, Guangdong, China

  • Affiliated Cancer Hospital of Xinjiang Medical University

    RECRUITING

    Ürümqi, Xinjiang, China

  • Beijing Cancer Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

  • Chongqing University Cancer Hospital

    RECRUITING

    Chongqing, Chongqing Municipality, China

  • Fujian Cancer Hospital

    RECRUITING

    Fuzhou, Fujian, China

  • Harbin medical university cancer hospital

    RECRUITING

    Harbin, Heilongjiang, China

  • Hunan Cancer Hospital

    RECRUITING

    Changsha, Hunan, China

  • Jiangxi Cancer Hospital

    RECRUITING

    Nanchang, Jiangxi, China

  • Jinan Central Hospital

    RECRUITING

    Jinan, Shandong, China

  • Peking University School and Hospital of Stomatology

    RECRUITING

    Beijing, Beijing Municipality, China

  • Shanghai East Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, China

  • Shanxi Cancer Hospital

    RECRUITING

    Xi'an, Shaanxi, China

  • Texas Oncology

    RECRUITING

    Dallas, Texas, 75251, United States

  • The First Affiliated Hospital of Zhengzhou University

    RECRUITING

    Zhengzhou, Henan, China

  • The University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • Union Hospital Tongji Medical College Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, China

  • West China Hospital of Sichuan University

    RECRUITING

    Chengdu, Sichuan, China

  • Zhejiang Cancer Hospital

    RECRUITING

    Hangzhou, Zhejiang, China

Conditions

Explore the condition pages connected to this study.