New study aims to help cancer survivors ditch opioids for good
NCT ID NCT06574009
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests four different approaches—behavioral therapy, physical therapy, medication changes, and buprenorphine rotation—to help cancer survivors reduce their opioid use while keeping pain under control. It involves 294 veterans who have finished cancer treatment but still struggle with chronic pain. The goal is to find which strategy works best to lower opioid doses without making pain worse.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Multimodal pain care (behavioral therapy, physical therapy, assistive devices, complementary therapies) and medication optimization (non-opioid drugs, buprenorphine rotation)
What this could lead to
If successful, this could provide a proven, safer way for cancer survivors to manage chronic pain without relying on opioids, reducing addiction and overdose risks.
What could go wrong
This is a Phase 4 trial, but it only includes veterans with certain cancers and no active disease, so results may not apply to all cancer survivors. The interventions may not work for everyone, and some may still need opioids.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Richard L. Roudebush VA Medical Center, Indianapolis, IN
NOT_YET_RECRUITINGIndianapolis, Indiana, 46202-2884, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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VA Ann Arbor Healthcare System, Ann Arbor, MI
RECRUITINGAnn Arbor, Michigan, 48105, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••