OPIOID DEPENDENCE
Clinical trials for OPIOID DEPENDENCE explained in plain language.
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New shots aim to outdo vivitrol for addiction treatment
Disease control Recruiting nowThis early-stage study tests two new long-acting injections, IVL3004 and IVL4002, in 40 healthy men aged 18-55. The goal is to see how the body processes these drugs compared to the approved medication Vivitrol, and to check for safety. If successful, these injections could offer…
Matched conditions: OPIOID DEPENDENCE
Phase: PHASE1 • Sponsor: Inventage Lab., Inc. • Aim: Disease control
Last updated May 17, 2026 02:06 UTC
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Can counseling and peer helpers boost opioid addiction treatment success?
Disease control Recruiting nowThis study looks at whether adding addiction counseling and a community peer guide to regular primary care helps people with opioid use disorder stay on their medication (buprenorphine) and keep up with doctor visits. About 70 adults with opioid dependence and other medical or so…
Matched conditions: OPIOID DEPENDENCE
Phase: NA • Sponsor: Oregon Health and Science University • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New program aims to keep young people off opioids
Disease control Recruiting nowThis study tests a community program for youth aged 12-17 with opioid use disorder. It combines medication, counseling, and peer support to help them stay in treatment and stop using opioids. Researchers will track how many stay in treatment and how many days they go without opio…
Matched conditions: OPIOID DEPENDENCE
Phase: PHASE4 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Magic mushroom therapy could help kick opioids for chronic pain
Disease control Recruiting nowThis study tests whether a combination of psilocybin (the active ingredient in magic mushrooms) and talk therapy can help adults with chronic pain safely reduce or stop their opioid painkillers. Ten participants will receive one or two psilocybin sessions over 8 weeks, with follo…
Matched conditions: OPIOID DEPENDENCE
Phase: PHASE2 • Sponsor: University of British Columbia • Aim: Disease control
Last updated May 07, 2026 18:42 UTC
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New patch could cut opioid addiction after ankle surgery
Symptom relief Recruiting nowThis study tests whether a 7-day buprenorphine skin patch can safely control pain after ankle fracture surgery and reduce the need for addictive opioids. About 100 adults who have never taken opioids before will receive either the patch or a placebo, along with standard pain care…
Matched conditions: OPIOID DEPENDENCE
Phase: PHASE4 • Sponsor: Jenna-Leigh Wilson • Aim: Symptom relief
Last updated May 17, 2026 02:05 UTC
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Could a seizure drug ease opioid-related pain in pancreatitis?
Symptom relief Recruiting nowThis early-stage study tests whether adding lacosamide, a seizure medication, to standard opioid therapy is safe and tolerable for people with long-term abdominal pain from chronic pancreatitis. About 24 adults will take the drug for 7 days and be monitored for side effects and p…
Matched conditions: OPIOID DEPENDENCE
Phase: PHASE1 • Sponsor: Indiana University • Aim: Symptom relief
Last updated May 14, 2026 12:03 UTC
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New program aims to help patients kick opioids after surgery
Symptom relief Recruiting nowThis study tests a program for adults who have chronic pain and take opioids before surgery. The program includes pain education, therapy, and a mobile app to help patients reduce opioid use and manage pain. Researchers will compare how many patients successfully wean off opioids…
Matched conditions: OPIOID DEPENDENCE
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 12, 2026 13:44 UTC
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New study aims to help cancer survivors break free from opioid dependence
Symptom relief Recruiting nowThis study tests four different programs to help cancer survivors who have been using opioids for a long time reduce their opioid use and better manage chronic pain. About 294 veterans who have finished cancer treatment and still have pain will try one of these programs. The goal…
Matched conditions: OPIOID DEPENDENCE
Phase: PHASE4 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Apr 30, 2026 15:50 UTC
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Brain wiring may predict opioid relapse risk
Knowledge-focused Recruiting nowThis study uses brain scans to see if patterns of brain activity can predict whether someone recovering from opioid addiction will relapse. Researchers will follow 240 adults who recently started medication treatment (methadone or buprenorphine) for six months. The goal is to bet…
Matched conditions: OPIOID DEPENDENCE
Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC