OPIOID DEPENDENCE
Clinical trials for OPIOID DEPENDENCE explained in plain language.
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New shot could help fight addiction cravings longer
Disease control Recruiting nowThis early study is testing two new long-acting injection versions of a medication called naltrexone, which is used to help manage opioid and alcohol dependence. The study will involve 40 healthy male volunteers to see how the body processes these new injections compared to the e…
Matched conditions: OPIOID DEPENDENCE
Phase: PHASE1 • Sponsor: Inventage Lab., Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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VA launches major study to break cancer Survivors' opioid dependence
Disease control Recruiting nowThis study aims to help cancer survivors who have chronic pain reduce their long-term opioid use safely. It will test four different treatment approaches, including specialized pain care and medication changes, to see which works best. The goal is to lower opioid doses by at leas…
Matched conditions: OPIOID DEPENDENCE
Phase: PHASE4 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New program aims to keep people in addiction treatment
Disease control Recruiting nowThis study is testing whether adding counseling and a community peer navigator to standard medication treatment helps people with opioid addiction and other health problems stay in treatment and engage more with their primary care. Researchers will compare this enhanced 'MOUD Plu…
Matched conditions: OPIOID DEPENDENCE
Phase: NA • Sponsor: Oregon Health and Science University • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Magic mushroom therapy tested to break opioid dependence
Disease control Recruiting nowThis small, early-stage study is testing whether therapy sessions guided by the psychedelic compound psilocybin can help people with chronic pain safely reduce or stop their opioid pain medication. The study will involve 10 adults who have previously struggled to taper off opioid…
Matched conditions: OPIOID DEPENDENCE
Phase: PHASE2 • Sponsor: University of British Columbia • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Houston launches emergency program to save youth from opioid crisis
Disease control Recruiting nowThis study tests a community program that helps young people with opioid addiction get treatment faster. The program sends outreach teams to connect youth with medication, counseling, and peer support right away. Researchers want to see if this approach helps young people stay in…
Matched conditions: OPIOID DEPENDENCE
Phase: PHASE4 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Mar 18, 2026 14:40 UTC
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Epilepsy drug trial offers hope for debilitating pancreatitis pain
Symptom relief Recruiting nowThis early-stage study is testing whether adding an existing epilepsy drug, lacosamide, to standard opioid painkillers is safe and tolerable for adults with chronic pancreatitis. The main goal is to see if the combination helps reduce severe abdominal pain and might allow patient…
Matched conditions: OPIOID DEPENDENCE
Phase: PHASE1 • Sponsor: Indiana University • Aim: Symptom relief
Last updated Mar 27, 2026 12:37 UTC
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Scientists scan brains to predict opioid relapse
Knowledge-focused Recruiting nowThis study aims to understand why some people relapse after starting medication treatment for opioid addiction. Researchers will use brain scans on 240 people recently starting treatment to look for patterns linked to staying drug-free. The goal is to learn how the brain changes …
Matched conditions: OPIOID DEPENDENCE
Sponsor: Yale University • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:09 UTC