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Massive study aims to unlock secrets of rare cancers

NCT ID NCT03739827

Recruiting now Knowledge-focused Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is collecting medical information and biological samples from up to 10,000 people with rare solid tumors, their relatives, and those with genetic mutations that raise cancer risk. Researchers hope to learn how these tumors develop and change over time. The goal is to improve screening, prevention, and treatment for rare cancers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could lead to better screening guidelines, earlier detection, and new treatments for rare solid tumors.
What could go wrong
This is an observational study, not a treatment trial. It will not directly benefit participants and may take many years to produce useful results.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer childhood neoplasm neoplasm refractory malignant neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MALIGNANT SOLID TUMORS OTHER NEOPLASMS SOLID TUMORS PEDIATRIC SOLID TUMOR REFRACTORY SOLID TUMORS SOLID TUMOR

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oregon Health and Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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