Vitamin B12 trial aims to stop Chemo's painful side effect
NCT ID NCT07423390
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether taking mecobalamin (a form of vitamin B12) can prevent or reduce nerve damage caused by taxane chemotherapy. About 326 adults with various solid tumors will take mecobalamin tablets or receive no preventive treatment during their chemo. The goal is to see if fewer people develop numbness, tingling, or pain in their hands and feet.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
mecobalamin (a form of vitamin B12)
What this could lead to
If it works, this could provide a simple, low-cost way to prevent painful nerve damage during chemotherapy.
What could go wrong
This is a single-center trial, and the benefit may be modest or not confirmed. Mecobalamin is generally safe but may not prevent all nerve symptoms.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Affiliated Cancer Hospital of Shandong First Medical University (Shandong Cancer Hospital)
NOT_YET_RECRUITINGJinan, Shandong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Affiliated Hospital of Qinghai University
NOT_YET_RECRUITINGXining, Qinghai, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Beijing Chaoyang Sanhuan Cancer Hospital
RECRUITINGBeijing, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Qinghai Red Cross Hospital
RECRUITINGXining, Qinghai, China
Contact Phone: •••-•••-•••• Email: •••••@•••••