New study aims to uncover cancer genes in underrepresented populations

NCT ID NCT04475640

Recruiting now Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is looking at how cancer genetic testing works in people from different ethnic backgrounds. Researchers will collect blood samples and genetic information from 1,800 adults with various solid tumors. The goal is to find cancer-related gene mutations and see if current testing guidelines miss some at-risk individuals, especially in ethnic populations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Genetic testing
What this could lead to: If successful, this could help identify cancer genes more accurately in ethnic populations, leading to better personalized screening and prevention.
What could go wrong: This is an observational study, not a treatment trial. It may not directly benefit participants, and results may not apply to all groups.

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Conditions

The condition(s) this trial relates to.

brain cancer breast carcinoma breast neoplasm cancer cancer of unknown primary site central nervous system cancer digestive system carcinoma female reproductive organ cancer head and neck carcinoma malignant urinary system neoplasm musculoskeletal system cancer neoplasm Neoplasms, Unknown Primary skin carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CARCINOMA CARCINOMA OF UNKNOWN PRIMARY CENTRAL NERVOUS SYSTEM CARCINOMA DIGESTIVE SYSTEM CARCINOMA GENITOURINARY SYSTEM CARCINOMA HEAD AND NECK CARCINOMA MALIGNANT BRAIN NEOPLASM MALIGNANT FEMALE REPRODUCTIVE SYSTEM NEOPLASM MALIGNANT MUSCULOSKELETAL NEOPLASM MALIGNANT SOLID NEOPLASM SKIN CARCINOMA

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Mayo Clinic in Arizona
RECRUITING

Scottsdale, Arizona, 85259, United States

Contact Email: •••••@•••••
Mayo Clinic in Florida
RECRUITING

Jacksonville, Florida, 32224-9980, United States

Contact Email: •••••@•••••

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