Virus injection takes on tough tumors in early trial

NCT ID NCT06368921

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase study tests a modified virus called VRT106, which is injected directly into tumors to kill cancer cells. It involves 30 adults with advanced solid tumors that haven't responded to standard treatments. The main goal is to check safety and find the best dose, while also looking at how the virus spreads and whether it helps fight the cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

VRT106 (a modified virus that targets and kills cancer cells)

What this could lead to

If it works, this could point toward a new treatment option for people with advanced solid tumors that haven't responded to standard therapies.

What could go wrong

This is a very early Phase 1 trial with only 30 participants, so safety and dosing are still being figured out. It may not shrink tumors or work for everyone, and there could be side effects from the virus or injection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SOLID TUMOR are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Cancer Hospital of Shandong First Medical University

    RECRUITING

    Jinan, Shandong, China

    Contact

  • Affiliated Cancer Hospital of Zhengzhou University

    RECRUITING

    Zhengzhou, Henan, China

    Contact

  • Sun Yat-sen University Cancer Center

    RECRUITING

    Guangzhou, Guangdong, China

    Contact Email: •••••@•••••