Ischemic stroke

This study tests a device called the Penumbra System with Thunderbolt Aspiration Tubing to remove blood clots in people having a severe stroke caused by a blockage in a large brain artery. The goal is to see if the device can safely and effectively restore blood flow within 8 hou…

This study explores whether combining a high-protein Mediterranean diet with resistance exercise can help people with heart disease build muscle and lower their risk of future heart problems. The trial enrolls adults who have completed cardiac rehab and may have low muscle mass w…

This study tests whether a three-month smartphone-supported walking program can improve daily step counts, psychological well-being, and body composition in adults with cardiovascular disease or type 2 diabetes. Participants use the Walk15 app to set personalized step goals and t…

This study tested a coaching program called MACRO-I for adults aged 70 and older who had a heart event. The program used coaches to guide patients through starting cardiac rehab, either at a center, at home, or a mix of both. 416 participants were split into the coaching group or…

This study tests whether a smart bracelet system can help hospitals treat stroke patients faster. The bracelets track where patients are in the emergency room and send alerts if treatment is delayed. The goal is to shorten the time between arrival and life-saving clot-busting the…

This phase 2 trial tested a new gel called OTR4132 in 60 people who had a stroke and received a clot-removal procedure. The gel is designed to help repair damaged brain tissue. Researchers measured neurological function at 24 hours and disability at 3 months to see if the gel imp…

This study tests whether combining two types of electrical stimulation can improve hand and arm movement in people who recently had a stroke. One stimulation is applied to the brain (tDCS) and the other to a nerve in the wrist. Participants receive five daily sessions, and their …

This study looked at how well a mechanical device works to remove blood clots from the brain during a stroke. Researchers followed 230 adults who had a stroke within the previous 8 hours and received the procedure. The goal was to see if the treatment helps patients recover and r…

This study tested whether Mongolian medicine ZhenBao Pills help people recover arm function after an ischemic stroke. 216 adults who had a stroke within the past 30 days took either the pills or a placebo twice daily for 90 days. The main goal was to see if arm movement improved …

This study tests whether using a blood test to guide antiplatelet medication can reduce the risk of a second stroke. People who have had a non-cardioembolic ischemic stroke and are already taking aspirin will be assigned to either continue standard aspirin or switch to a differen…

This study tested a soft robotic sock called VACOM in 19 stroke patients who had trouble moving their ankle. The sock gently moves the ankle to prevent stiffness and improve blood flow, aiming to reduce the risk of blood clots and contractures. The trial is complete, but results …

This study tested whether giving a powerful cholesterol-lowering drug (evolocumab) along with standard statins within 48 hours of a stroke could prevent early neurological decline. It included 429 adults with moderate to severe narrowing of brain arteries. The goal was to see if …

This study tested a drug called Edaravone (MCI-186) in 36 people who had an acute ischemic stroke. The goal was to check the drug's safety and how the body processes it. Participants received either Edaravone or a placebo through an IV over 72 hours. The trial was completed, but …

This study looked at whether a therapeutic education program, added to standard medical care, helps people who have had a heart attack or stroke better control their risk factors over one year. About 202 adults aged 18-75 took part. The goal was to see if the program improves phy…

This study tested a new intensive therapy called I-ACQUIRE for infants aged 8 to 36 months who had a stroke around birth and have weakness on one side. The therapy involves guided play and movement exercises for either 3 or 6 hours a day, 5 days a week for 4 weeks. Researchers co…

This study tested whether the drug rivaroxaban works as well as warfarin to prevent further brain damage in people who have had a stroke due to antiphospholipid syndrome (APS), a condition that causes abnormal blood clotting. About 40 participants took either rivaroxaban or warfa…

This completed study tested a new device called the Supernova stent retriever in 55 people with severe stroke caused by a large blood clot in the brain. The device is threaded through blood vessels to grab and remove the clot, restoring blood flow. Researchers measured how often …

This study tested a new way of caring for stroke patients that brings together doctors, nurses, and family members using technology and teamwork. About 1,200 adults who had a stroke took part. The goal was to see if this coordinated care helps people recover better and have a hig…

This study looked at whether a procedure to remove a blood clot from the brain (endovascular therapy) works better than medication alone for people with mild stroke symptoms and a visible clot. About 4,800 adults with mild stroke were included. The goal was to see which approach …

This study tested a 6-month program called TEAM designed to help African-American men who have had a stroke or mini-stroke manage their health better. The program included group sessions with a nurse and peer educators, focusing on lifestyle changes to lower blood pressure and ch…

This completed trial tested whether combining a gentle brain stimulation technique called tDCS with intensive rehabilitation can improve hand function in children with hemiplegic cerebral palsy caused by perinatal stroke. 89 children participated, and the study measured changes i…

This study tested whether adding dornase alfa (a drug used for cystic fibrosis) to standard clot-busting treatment could improve blood flow before a clot removal procedure in people having a major stroke. 330 adults with acute ischemic stroke and a large vessel blockage were enro…

This study tested whether colchicine, a drug used for gout, can reduce inflammation in the arteries of people with diabetes who recently had a heart attack or stroke. Researchers used a special PET scan to measure inflammation in the blood vessels. 115 participants were randomly …

This study tested whether a 40-hour, 8-week cognitive telerehabilitation program could reduce the risk of memory and thinking problems after a stroke. 86 adults who recently had a stroke were randomly assigned to either the home-based brain training or standard care. The program …

This study tested a once-daily pill called orforglipron against insulin glargine in nearly 2,750 adults with type 2 diabetes, obesity or overweight, and increased cardiovascular risk. The main goal was to see if orforglipron could reduce major heart events like heart attacks or s…

This pilot study tested whether low-frequency magnetic stimulation (rTMS) applied to the brain within 48 hours of an acute ischemic stroke could reduce the growth of damaged tissue and lower disability. Sixty adults aged 18–80 with moderate to severe strokes were enrolled. The tr…

This study tested whether low-frequency magnetic brain stimulation (rTMS) can improve recovery in 60 people who had a severe stroke and received emergency treatment to reopen blocked arteries. Participants received either real or sham stimulation for 3 days after their procedure.…

This study tested two blood thinners—tirofiban and aspirin—in 240 stroke patients who also had a severe blockage in the neck artery. The goal was to see which drug better prevents the artery from reclosing after emergency surgery, while also checking for bleeding risks. Results w…

This study tested a new medical wire, called the Tarvos Microguidewire, used during surgery on blood vessels in the brain. The wire helps doctors guide other tools to the right spot. Researchers looked back at records of 121 patients who had this wire used in their surgery for co…

This study tested whether giving heparin (a blood thinner) during brain angiography can prevent the radial artery in the wrist from becoming blocked afterward. The trial involved 440 acute stroke patients and compared heparin to a placebo. The goal was to see if heparin reduces a…

This study tested whether adding sodium sivelestat, a drug that reduces inflammation, to standard mechanical thrombectomy could improve outcomes in 20 stroke patients with large vessel occlusion. The drug aims to prevent 'futile recanalization,' where blood flow is restored but p…

This study tested whether a year of twice-weekly resistance training could protect brain health and thinking skills in 91 older adults with vascular cognitive impairment, a condition linked to small strokes. Participants were randomly assigned to either resistance training or a s…

This early study tested a new device that cools the brain in 8 people who had a stroke caused by a large blood clot. After doctors removed the clot, the device cooled the brain for 30 minutes to try to protect it from further damage. The main goal was to see if the cooling was sa…

This study tested whether using a special tongue brush (Orabrush) can lower the chance of aspiration pneumonia and improve swallowing in people who had a stroke. Researchers enrolled 252 stroke patients and compared those who used the brush to those who did not. The goal was to s…

This study tested whether using a balloon-guided catheter helps doctors remove blood clots more effectively in people having a stroke. 110 adults with acute ischemic stroke were randomly assigned to receive clot removal with either a balloon-guided or standard catheter. The main …

This study tested whether giving the blood-thinning drug tirofiban after mechanical clot removal improves outcomes for people with severe stroke. Over 1,300 participants were randomly assigned to receive tirofiban or a placebo. The goal was to see if more patients could live inde…

This study tested a new device called the Millipede System in 246 stroke patients with large blood clots in the brain. The device is designed to remove clots and restore blood flow. Researchers measured how often blood flow was successfully restored and tracked any side effects. …

This completed trial tested a new stent (SINOMED SR) for removing blood clots in 218 people with acute ischemic stroke. The stent was used within 24 hours of symptom onset. The main goal was to see if the stent could successfully reopen blocked brain arteries. Researchers also tr…

This study tested an experimental drug called SCP776 in 120 adults having emergency surgery to remove a blood clot after a severe stroke. The goal was to see if the drug is safe and helps protect the brain from further damage. Participants received either the drug or a placebo, a…

This study tested whether giving N-Acetylcysteine (NAC) intravenously soon after an acute ischemic stroke could improve outcomes. Only 4 adults with moderate to severe stroke were enrolled. Researchers measured stroke severity and disability at 30 and 90 days. The trial is comple…

This study tested whether intensive dental cleaning and oral hygiene advice can improve gum health and also affect markers of heart disease and type 2 diabetes. About 200 adults with gum disease and either heart disease or diabetes (or prediabetes) took part. Researchers measured…

This early-stage study tested whether a single intravenous infusion of stem cells from human umbilical cord tissue is safe for people who had an ischemic stroke 3 to 6 months earlier. 18 participants were monitored for side effects and any improvement in daily function. The goal …

This phase 3 trial tested whether giving a clot-dissolving drug called tenecteplase directly into the brain artery can improve blood flow in stroke patients who still have blockages after standard mechanical clot removal. 156 adults with acute ischemic stroke were randomly assign…

This study tested a brain-computer interface (BCI) combined with functional electrical stimulation (FES) to help stroke survivors with foot weakness walk better. 62 adults who had a stroke at least 6 months prior and had trouble walking participated. The therapy used brain signal…

This small completed study looked at a blood filtering procedure called double-filtration plasmapheresis (DFPP) in 5 kidney dialysis patients with very high levels of lipoprotein(a), a fatty substance linked to heart disease and blood clots. The goal was to see if DFPP could lowe…

This study tested a device called the Lariat to close off a small pouch in the heart (the left atrial appendage) in people with atrial fibrillation who cannot take blood thinners. The goal was to reduce the risk of stroke. Nine participants were enrolled, and the study measured h…

This study tested a program to help people with heart disease, stroke, or heart failure in India. The program used non-physician health workers, text messages about healthy living, and a computer tool to help doctors make decisions. 410 adults took part to see if the program impr…

This Phase IIa trial tested a single dose of LT3001, a new drug, in 24 people who had an acute ischemic stroke within the past 24 hours. The main goal was to see if the drug causes dangerous bleeding in the brain compared to a placebo. Researchers also looked for early signs that…

This study compares two ways to remove large blood clots from the brain during a stroke: direct aspiration (ADAPT) and using a stent retriever. About 381 adults with stroke caused by a blocked artery in the front part of the brain took part. The goal is to see which method clears…

This study tested whether a drug called dornase alfa (Pulmozyme) can help restore full blood flow to the brain after a stroke. The trial included 39 people who had a stroke and were already receiving standard clot-busting medication and a mechanical clot removal procedure. The go…

This study tested whether giving two blood thinners (ticagrelor and aspirin) early, along with standard clot-busting treatment, helps people recover better after a stroke. Over 1,300 patients with mild to moderate stroke were treated within 6 hours of symptoms. The goal was to se…

This study tested whether using a bronchoscope (a thin tube with a camera) to clean the lungs could help people who develop pneumonia and swallowing problems after a stroke. 50 patients were split into two groups: one received standard care, and the other also got 1-2 bronchoscop…

This Phase 2 trial tested the safety of an experimental drug called RNS60 in 83 people having a severe stroke caused by a large blood clot. Participants received either RNS60 or a placebo as a 48-hour infusion, starting within 30 minutes of consent. The main goal was to check for…

This study tested whether a drug called alirocumab, which lowers cholesterol, can reduce heart disease risk in people with HIV. The trial involved 118 adults aged 40 and older with well-controlled HIV and high heart disease risk. Participants received either alirocumab or a place…

This study tested a clot-dissolving medicine called alteplase in 58 people who had a stroke caused by a blocked artery. The goal was to see how well it reopened blocked brain arteries and improved patients' ability to function three months later. The results were compared to exis…

This study tested a lower dose (0.6 mg/kg) of the clot-busting drug alteplase in 103 Japanese patients who had a stroke within the previous 3 hours. The goal was to see if this dose was both safe and effective for this population. Results focused on how many patients had little t…

This study compared two medications, edaravone and sodium ozagrel, for treating acute ischemic stroke. Researchers wanted to see which drug helped more people recover with little or no disability three months after treatment. The study included 401 adults who started treatment wi…

This completed trial looked at whether taking two cholesterol-lowering drugs (rosuvastatin and ezetimibe) is more effective and safer than taking just one (rosuvastatin) for people with heart disease. 66 adults with high cholesterol were randomly assigned to one of the two treatm…

This study tested whether intensive, coordinated follow-up by nurses, doctors, and pharmacists over two years helps people recover better after a stroke or heart attack compared to standard care. Researchers enrolled 859 participants and measured quality of life and healthcare co…

This study tested whether adding Mexidol to standard stroke care helps people recover better after a first ischemic stroke. 304 adults who had a stroke within 48 hours were given either Mexidol or a placebo for about 10 weeks. Researchers measured disability, neurological symptom…

This Phase 2 trial tested a drug called LT3001 in 89 people who had an acute ischemic stroke. Participants received either the drug or a placebo within 24 hours of their stroke. The study found no serious drug-related side effects, suggesting LT3001 is safe. Researchers are now l…

This Phase 2 trial tested an experimental drug called elezanumab in 121 people who had an acute ischemic stroke. The goal was to see if it could safely improve neurological function and reduce disability compared to a placebo. Participants received the drug or placebo by IV withi…

This study tested a technique called ischemic postconditioning in 60 stroke patients who already had a procedure to remove a clot. After the clot was removed, doctors briefly stopped and restarted blood flow in the affected artery four times. The goal was to see if this extra ste…

This study looked at 51 stroke patients to see which therapy—constraint-induced movement therapy or task-oriented training—works better for arm function after a Botox injection. Both therapies aim to improve movement and reduce muscle tightness. The results help doctors choose th…

This study tested a new medicine called MLC1501 to help people recover after a stroke. 303 adults who had a stroke within the past 2 to 10 days took either a high dose, low dose, or a placebo pill twice a day for 24 weeks. The main goal was to see if MLC1501 improves motor functi…

This study tested whether Enhanced External Counterpulsation (EECP) therapy, a non-invasive treatment using leg cuffs to boost blood flow, can improve brain circulation in people with severe narrowing of key brain arteries. The 130 participants had recently experienced a stroke o…

This study tested a clot-dissolving drug called non-immunogenic staphylokinase in over 23,000 adults who had an acute ischemic stroke within the last 4.5 hours. The goal was to see how safe and effective the drug is in everyday hospital practice. Researchers measured how many pat…

This study tested whether a clot-busting drug called rhTNK-tPA can help people having a stroke when given 4.5 to 24 hours after symptoms begin. It included 570 adults with a stroke that did not involve a large blocked artery. The goal was to see if the drug leads to better recove…

This study looked at 260 people having emergency stroke treatment to remove a clot. Some were given sedation (awake but relaxed) and others were put under general anesthesia (completely asleep). The goal was to see which approach leads to better recovery and fewer complications a…

This phase 3 trial tested a drug called tenecteplase in 452 people with a severe type of stroke caused by a blockage in the basilar artery at the back of the brain. Participants received either tenecteplase or the current best treatment (which could include another clot-buster or…

This study tested a procedure called rapid local ischemic postconditioning in 25 people who had a stroke and successful clot removal. Right after reopening the blocked artery, doctors briefly inflated and deflated a balloon in the neck to temporarily stop blood flow, aiming to he…

This study looked at 391 people with a type of stroke caused by a blockage in a major brain artery, treated 4.5 to 24 hours after symptoms started. Half got a clot-busting drug called tenecteplase followed by a mechanical clot removal procedure, while the other half had the proce…

This study looked at 345 people with a severe stroke caused by a blockage in the basilar artery, a major blood vessel in the brain. It compared two treatments: giving a clot-busting drug followed by a procedure to remove the clot, versus doing the procedure alone. The goal was to…

This study looked at whether a medication called Renexin CR can help people who have had a certain type of stroke (non-cardioembolic ischemic stroke) within the last 72 hours. The goal was to see if it reduces the chance of getting worse in the hospital or having another stroke w…

This study looked at 1,424 veterans at high risk for heart problems who had major surgery. It compared two approaches to blood transfusion: a liberal strategy (transfusing when hemoglobin drops below 10) versus a restrictive strategy (transfusing only when hemoglobin drops below …

This study tested whether lying in a head-down position (10 degrees) after successful stroke treatment improves recovery. 90 adults with large-vessel stroke were randomly assigned to head-down or standard care. Researchers measured changes in stroke severity and functional outcom…

This early-stage study tested a drug called PP-007 in 24 people having an acute ischemic stroke. The drug is designed to carry oxygen to the brain. Researchers checked if adding it to standard treatments like clot-busting drugs or clot removal was safe. The goal was to see how th…

This study tested a new drug called SHPL-49 in 270 people who had an acute ischemic stroke. Participants received either the drug or a placebo as an IV infusion twice daily for 7 days. The goal was to see if the drug helps improve recovery and is safe to use.

This study tested a new medicine called HRS-7450 in 64 adults who had a stroke within the past 4.5 to 24 hours. The goal was to check if the drug is safe and might help restore blood flow to the brain. Researchers monitored for bleeding and other side effects to see if the treatm…

This completed study tested a new device designed to remove blood clots from the brain in people having a severe stroke. Eight patients were treated within 8 hours of symptoms starting. Researchers measured how well the device restored blood flow and tracked any serious side effe…

This study tested whether trimetazidine, a drug usually used for heart conditions, can improve outcomes in people who had an acute ischemic stroke. 60 adults were enrolled within 6-12 hours of their stroke. Researchers measured inflammation levels, stroke severity, and disability…

This study looked at whether measuring two proteins in the blood (GST-π and PRDX1) can accurately determine if a stroke occurred within the last 4.5 hours. That time window is critical because it determines if patients can receive clot-busting medication. Researchers enrolled 935…

This pilot study tested whether a quick, 20-second ultrasound of the brain's blood vessels could help paramedics identify patients with a severe stroke caused by a large blocked artery. The study included 60 participants: healthy volunteers and suspected stroke patients. Research…

This study tested whether a special CT scan done in the procedure room can accurately detect bleeding in the brain of stroke patients. The goal is to speed up diagnosis and treatment by avoiding extra trips to the regular CT scanner. 252 adults with stroke symptoms were enrolled …

This study looked at whether a special eye scan (SS-OCTA) can detect signs of cardiovascular disease. Researchers compared retinal blood vessel changes to results from a standard carotid ultrasound in 42 adults. The goal was to see if the eye scan could predict the presence or se…

This study looked at whether a special type of CT scan (dual-energy CT) can more accurately tell the difference between bleeding and harmless contrast dye in the brains of stroke patients after treatment. About 189 adults who had a stroke and received clot-busting drugs or a clot…

This study tested a device called NIRSITX that uses light to measure oxygen levels in the brain. Researchers compared oxygen readings from the injured side of the brain to the healthy side in 35 adults who had a stroke within the past week. The goal was to see if the device could…

This study tested whether a special ultrasound of the eye's main artery can help doctors diagnose increased pressure inside the skull. Researchers measured blood flow in the central retinal artery of 66 patients with stroke or traumatic brain injury. The goal was to see if change…

This study combined data from nearly 4,000 stroke patients to see how often a heart CT scan finds blood clots that standard ultrasound might miss. Researchers looked at how well this quick scan, done during the initial stroke workup, detects clot sources in the heart. The goal is…

This study tested a wearable heart monitor called Cardea SOLO against a standard 12-lead EKG to see if it could better detect paroxysmal atrial fibrillation (a temporary irregular heartbeat) in people who had a stroke of unknown cause and have an enlarged heart. 257 participants …

This study looked at whether a panel of blood biomarkers can quickly identify stroke patients who have a large vessel occlusion (a major blockage) and would benefit from a specialized clot-removal procedure. Researchers enrolled nearly 3,900 adults with stroke symptoms and tested…

This study tested whether an ultrasound of the optic nerve sheath (the lining around the nerve connecting the eye to the brain) can accurately detect dangerously high pressure inside the skull in children. Researchers measured the nerve sheath diameter in 230 children with brain …

This study tested a drug called conestat alfa in 141 people undergoing a minimally invasive heart valve replacement (TAVI) for severe aortic stenosis. The goal was to see if the drug could reduce the risk of small strokes and kidney damage that can happen after the procedure. Par…

This study looked at how often older adults with heart disease risk factors should exercise to improve fitness and blood pressure. Twenty-two participants did combined training either twice or three times a week for 12 weeks. The goal was to see which frequency worked better for …

This study tested an 8-week digital lifestyle program called MYCardio-PEER for low-income adults at risk of heart disease. Participants received weekly videos and infographics on healthy eating and exercise, plus group chats with peer leaders. The goal was to see if the program i…

This study looked at whether a home-based physical activity program and computer-based cognitive training could help prevent memory loss in older women with heart disease. 253 women aged 65 and older participated. The goal was to see if these lifestyle changes could improve memor…

This study tested a new daily pill called asundexian in over 12,000 people who recently had a stroke or mini-stroke caused by a blood clot from outside the heart. The goal was to see if adding asundexian to standard antiplatelet therapy could prevent another stroke without increa…

This completed study tested whether sending behavioral nudges through Denmark's official electronic letter system could increase flu vaccination among adults aged 18-64 with chronic diseases. Over 300,000 participants were randomly assigned to receive different types of letters o…

This study tested whether fast arm movement training helps people who had a stroke regain arm function better than standard accuracy training. 44 chronic stroke survivors with mild to moderate arm weakness participated. The training focused on moving quickly, and researchers meas…

This pilot study tests a home-based rehabilitation program called TASSRET for stroke survivors who have limited access to physiotherapy. Fifty participants will use either a video or a manual guide to practice specific tasks aimed at improving arm and leg function, balance, and q…

This study tested whether adding augmented cues—like visual and auditory feedback from a sensor-based glove—to standard physical therapy could improve hand function in people recovering from a stroke. Fifty patients with subacute ischemic stroke were randomly assigned to receive …

This study tested a treatment that shines a laser light inside a vein to help people recover after an ischemic stroke. 22 adults with mild to moderate stroke symptoms received the laser therapy. Researchers measured their disability and stroke symptoms before treatment, and again…

This study looked at whether giving a sour liquid early on can improve swallowing function in people who have trouble swallowing after a stroke. Researchers worked with 95 patients who had an acute ischemic stroke and developed dysphagia. They measured swallowing ability at the s…

This study tested whether task-oriented gait training combined with core stabilization exercises can improve mobility, balance, and walking in people who had a stroke. Fifty-four adults aged 45-75 with left-side weakness took part in an 8-week program. The goal was to see if thes…

This study tested whether a 24-session program of functional electrical stimulation (FES) on the tibial nerve could improve walking in people who had a stroke more than a year ago. Fifteen participants with chronic stroke and leg weakness were enrolled. The main goal was to see i…

This study looked at whether electroacupuncture (a type of acupuncture with mild electric pulses) can lower inflammation and help people recover after a stroke. 17 adults who had their first ischemic stroke took part. Researchers measured changes in symptoms and blood markers to …

This study tested whether a chin tuck against resistance (CTAR) exercise can improve swallowing in stroke patients with dysphagia. 112 participants did the exercise daily for two weeks alongside standard rehab. Researchers measured swallowing ability with a water test and a quali…

This study looked at two methods to reduce pain after heart surgery through a cut in the chest bone. 120 adults received either a nerve block near the breastbone, pain medicine injected into the wound, or standard painkillers. Researchers measured pain levels using a saliva test …

This completed trial looked at how two different feeding tubes affect the mental health of 156 stroke patients with swallowing problems. One group used a standard nasogastric tube, the other an intermittent oro-esophageal tube. Researchers measured anxiety, depression, and feelin…

This study tested whether chewing real food (like candies and dumplings) before meals can improve swallowing and quality of life in stroke patients who have trouble swallowing. 120 patients were split into two groups: both got standard rehab and tube feeding, but one group also c…

This completed trial tested an 8-week program called Healing Hearts Together (HHT) for couples where one partner has heart disease. 474 couples attended weekly group sessions focused on communication, emotional support, and heart health. The goal was to see if the program improve…

This study tested a simple, non-invasive procedure called ischemic conditioning in 132 chronic stroke survivors. The procedure involves inflating a blood pressure cuff on the affected leg to briefly stop blood flow, then releasing it, repeated several times. Researchers measured …

This study tested whether vibration training can help people who recently had a stroke improve leg muscle strength, daily function, and mood. 148 patients took part. The approach uses whole-body vibration to stimulate muscles, aiming to speed recovery after a stroke.

This study tested whether a non-immersive virtual reality system (MindMotion GO) could help people with chronic stroke improve arm function better than standard occupational therapy. Twenty-six adults who had a stroke more than 6 months ago participated in 8 weeks of training. Th…

This study tested a new program called CATCHES for people who had a stroke and are afraid of falling. The program combines physical therapy at home with coaching to reduce fear. 30 adults who had a mild to moderate stroke took part. The goal was to see if the program is practical…

This study tested whether a 20-minute session of nurse-led spiritual care, including prayer and relaxation techniques, could help heart surgery patients feel less anxious and have more stable blood pressure and heart rate before their operation. 248 adults in Indonesia took part.…

This study tested two methods to help people regain arm movement after a stroke: looking at a mirror to trick the brain, or using a robotic hand glove that mimics the healthy arm. Thirty adults who had a stroke within the past year took part. Both groups also received standard ph…

This study tested whether adding a drug called Cytoflavin to standard physical rehab helps stroke survivors recover better. Cytoflavin is an antioxidant that may protect brain cells and improve learning of new skills. The trial involved 240 adults aged 40-80 who had a stroke 2 we…

This study tested a non-invasive brain stimulation technique called continuous theta-burst stimulation (cTBS) in 60 people who had a stroke within the past two weeks and had moderate to severe arm weakness. The stimulation was guided by brain scans to target areas involved in mov…

This study looked at whether starting more frequent or intense physical therapy within the first day after a stroke helps patients regain movement and balance. 102 adults with acute stroke were split into groups receiving standard care, more sessions, harder exercises, or both. R…

This study looked at whether listening to self-chosen Italian music during and after a stroke hospital stay can improve mood, reduce anxiety and depression, and boost overall well-being. 150 stroke patients were randomly assigned to either regular music listening or standard care…

This study tested whether combining a drug called galantamine with a specific cognitive training program could improve thinking skills in adults aged 35-70 who had a first stroke 3 months earlier. 47 participants received either the drug or a placebo, plus brain training, and wer…

This study tested whether a 3-month yoga program could improve physical and mental health in adults over 65 who had recently finished cardiac rehab. Participants attended yoga twice a week. Researchers measured balance, muscle strength, anxiety, and mood. The goal was to see if y…

This study tested whether a gentle electrical current applied to the scalp (tES) can improve movement and thinking in people who had a stroke. Sixty adults who had a stroke between 2 weeks and 2 years ago received real or fake stimulation while doing physical therapy. Researchers…

This study tested whether adding vibration therapy to standard rehabilitation could improve leg muscle strength, daily function, and emotional well-being in people who recently had a stroke. 115 hospitalized patients were randomly assigned to receive either standard care alone, s…

This study tested whether adding art therapy to standard speech rehab could help people who recently had a stroke and now have trouble speaking (aphasia). Fifteen participants received 12 art therapy sessions alongside their usual therapy. Researchers used brain scans to see if a…

This small study tested whether adding mild brain stimulation (tDCS) to a computer-based naming therapy helps Cantonese-speaking adults with aphasia after stroke find words more quickly and accurately. Six participants completed two 5-day therapy blocks—one with real stimulation …

This study tested a therapy called cognitive multi-sensory rehabilitation (CMR) in 40 people who had a stroke 6 to 18 months earlier. The therapy uses movement awareness and discrimination exercises to help the brain and arm work together. Participants received 12 sessions over f…

This study tested whether playing special rehabilitative games (SmartPose) could help stroke survivors recover arm and hand function. 34 people who had an ischemic stroke took part. One group did standard therapy plus SmartPose games, while the other did only standard therapy. Th…

This study tested whether adding mirror therapy to Botox injections can better reduce arm spasticity in stroke survivors. Thirty patients who had a stroke at least three months earlier received Botox injections and then either mirror therapy or a sham treatment. Researchers measu…

This study looked at whether different types of physical exercise can help adults recover from a mild traumatic brain injury (concussion). 37 adults who had a concussion within the past year took part in a 3-month program of either balance or aerobic exercises. Researchers measur…

This study tested whether training one leg at a time on a treadmill improves walking and balance in stroke survivors more than standard two-legged training. 63 people who had an ischemic stroke at least 3 months prior took part. They did either unilateral step training, rhythmic …

This study tested whether kinesio taping (a special elastic tape placed on the skin) can improve arm and hand function, reduce pain, and boost mood in people who recently had a stroke. 26 adults with arm weakness were randomly assigned to get either real kinesio taping or a fake …

This study tested whether a robotic device called Luna EMG, which uses muscle signals to assist movement, can improve walking and balance in people recovering from a stroke. 62 older adults with leg weakness after a stroke were randomly assigned to get either robotic training plu…

This study looked at 34 adults with acute ischemic stroke and very high blood pressure. Researchers compared two drugs, nicardipine and labetalol, to see which one lowered blood pressure faster before stroke treatment. The goal was to find the best way to quickly and safely get b…

This study tested whether giving a very high dose of lovastatin (a common cholesterol drug) for 3 days after a stroke is safe. 162 stroke patients received either the high-dose drug or a placebo within 24 hours of symptoms. The main goal was to check for liver or muscle damage, w…

This study tested a 9-week internet-based cognitive behavioral therapy (CBT) program designed to reduce stress, anxiety, and depression in people with stable heart disease. 215 adults with heart disease and elevated stress or mood symptoms took part. The program was personalized …

This study looked at whether giving the drug butylphthalide earlier (within 3 hours of a stroke) helps patients recover better than giving it later (3-6 hours). The trial involved 204 adults with acute ischemic stroke. Researchers measured recovery using standard disability and n…

This study looked at whether starting gentle exercise soon after a stroke helps patients regain daily living skills, feel less anxious or depressed, and improve their quality of life. 102 adults with acute stroke took part. The results suggest early mobilization may support both …

This study tested whether adding a gentle brain stimulation technique (tDCS) to physical therapy could improve walking, balance, and leg strength in people who had a stroke. 34 adults with sub-acute or chronic stroke participated. The goal was to see if this combination helps the…

This study tested whether a brain-computer interface (BCI) system could help stroke survivors recover arm function. 84 participants with arm weakness after a stroke used the BCI to control muscle stimulation with their brain signals. The study measured improvements in arm movemen…

This study looked at ways to help people who had a stroke use a CPAP machine for sleep apnea during their rehab stay. Sleep apnea is common after stroke and can slow recovery. The researchers tested different approaches to improve how often patients used the CPAP machine over thr…

This study tested whether a non-invasive brain stimulation technique called tDCS, combined with balance and walking exercises, could help stroke survivors improve their mobility and thinking. Thirty adults who had a stroke participated. The results suggest tDCS may enhance rehabi…

This study tested a 6-month program for 92 stroke survivors in Vietnam. The program included regular health checks, personalized rehabilitation exercises, and motivational interviewing to support mental health. Participants were compared to those receiving standard care. The goal…

This study tested whether adding virtual reality (VR) driving simulations to standard cardiac rehabilitation helps heart surgery patients feel less anxious and depressed. Sixty adults recovering from heart surgery took part. The results suggest VR can improve emotional well-being…

This study explored how family members share health information about genetic diseases like sickle cell, diabetes, and cancer. Over 1,000 adults completed surveys or interviews about their family health history and support. The goal was to understand social and relational factors…

This study tested whether a video call between paramedics and a stroke specialist can help decide the right treatment—like clot-busting drugs or clot removal—before the patient arrives at the hospital. About 215 adults with suspected stroke took part. The goal was to see if remot…

This completed study looked at 140 stroke patients to understand what affects how long they stay in the hospital for rehabilitation. Researchers measured things like functional independence, balance, mental state, and depression in both patients and caregivers. The goal is to hel…

This study followed 67 children with sickle cell disease who had a high risk of stroke. Researchers compared those who received a bone marrow transplant to those who got standard care, checking brain scans and thinking skills 9-10 years later. The goal was to see which approach b…

This pilot study tested whether giving inhaled nitric oxide gas during laparoscopic surgery could protect blood vessels and organs in 40 adults with heart disease. Half received the gas through their breathing tube during surgery, and half received standard care. Researchers meas…

This study looked at whether a substance in the blood called D-dimer can help predict how well people recover after a stroke. Researchers measured D-dimer levels in 102 stroke patients who had received treatment to restore blood flow. They then compared these levels with standard…

This study looked at whether using best-practice physical therapy and giving stroke survivors an activity monitor can help them walk better. About 306 people who had a stroke and were in rehab took part. The main goal was to see if they could walk farther in 6 minutes after the p…

This study tested whether a brain-computer interface (BCI) device is ready for commercial use to help people with minimal movement communicate. Researchers worked with 8 device users, plus speech therapists and support staff, to evaluate how well the device worked at home. The go…

This study tested a new, powerful MRI scan on 56 stroke patients to see if it could detect subtle brain damage not visible on standard scans. The goal was to better understand how much brain tissue is truly saved after treatment. The findings could help doctors predict recovery m…

This study tested a 4-hour head ultrasound (transcranial-holter) to detect tiny blood clots in people who recently had a stroke. The goal was to see if this test could help doctors find the exact cause of the stroke, which is important for choosing the right treatment to prevent …

This study tested whether daily mood check-ins via a mobile app could help predict and prevent depression in people who recently had a stroke. Over 400 participants used the app for three months while researchers tracked their emotional symptoms. The goal was to see if this kind …

This study looked at 150 Caribbean Hispanic adults with heart disease or stroke risk who take the blood thinner clopidogrel. Researchers wanted to see if certain gene variants affect how well the drug works. The goal is to understand why some people get less benefit and to pave t…

This completed study looked at how rising temperatures affect people with chronic conditions like heart disease, diabetes, and depression. Researchers in Germany and Italy surveyed 176 patients to see what symptoms they experienced during heat and what protective steps they took.…

This small pilot study tested whether a non-invasive eye scan called OCTA can detect changes in the brain related to stroke and other neurological conditions. Researchers compared eye scans from 7 people with brain diseases and healthy volunteers. The goal was to gather early dat…

This study looked at 70 people who had a tissue heart valve replacement. It compared two common blood-thinning treatments (high-dose aspirin alone vs warfarin plus low-dose aspirin) to see which one better prevented tiny blood clots from traveling to the brain. Researchers used u…

This study checked how well over 5,000 heart patients follow their prescribed medicine routine. Researchers asked patients about their medication habits and any side effects. The goal was to understand how many patients do not take their medicines as directed.

This completed study looked at 192 adults with acute ischemic stroke to see if large swings in blood sugar (glycemic variability) are linked to worse outcomes, including death and disability. Participants wore a continuous glucose monitor for 96 hours. The goal was to understand …

This study tested a tool called the TriAGE+ score to see how well it predicts stroke risk in 818 emergency room patients with dizziness. Dizziness can be a sign of a stroke, but it is often missed. The goal was to check if the score is safe and reliable for use in busy ERs to hel…

This study looked at 38 people who had a first stroke in the cerebellum, a brain area involved in mood. Researchers used interviews and smartphone tracking to measure depression, anxiety, and apathy in daily life. The goal was to better understand how these mood problems develop …

This completed study followed 550 people who had a stroke within the last 48 hours. Researchers wanted to understand why some patients recover better than others by looking at their medical history, lifestyle, and blood markers. The goal is to find out what factors protect the br…

This pilot study tested a web-based tool designed to improve communication and decision-making between doctors and families of patients with severe acute brain injuries, such as stroke or traumatic brain injury. The tool helps prepare families for their role as decision-makers an…

This study adapted several questionnaires that measure arm and hand function after a stroke into Polish, and checked how reliable and accurate they are. One hundred people who had an ischemic stroke at least six months ago took part. The goal was to give Polish-speaking patients …

This early-stage study tested the safety and tolerability of a new drug called HRS-8829 in 83 healthy adults aged 18 to 55. The drug is being developed for acute ischemic stroke. Participants received either the drug or a placebo, and researchers monitored side effects and how th…

This study tested a program where doctors refer inactive people with chronic diseases (like diabetes, heart disease, or obesity) to an exercise professional for personalized counseling. The goal was to see if this referral scheme helps people become more active compared to just g…

This study tested a new ultrasound technique called ultrasound localization microscopy (ULM) to see very small arteries in the brain. Researchers used it on 24 people who had a stroke or Moya Moya disease. The goal was to see if ULM could find more tiny arteries than standard MRI…

This study looked at 332 stroke patients to see if general anesthesia or conscious sedation is better during a procedure to remove blood clots from the brain. The goal was to find which method leads to better recovery and fewer complications within the first week. The results cou…

This study followed 82 people with blocked arteries supplying the back of the brain to see if low blood flow raises the risk of stroke or mini-stroke. Participants had already experienced a stroke or transient ischemic attack (TIA) and had at least 50% blockage in those arteries.…

This study checked whether the Turkish version of the Cardiac Depression Scale (CDS) works well for people with heart disease. Researchers tested 360 Turkish adults with various heart conditions to see if the scale accurately measures depression. The goal is to give doctors a rel…

This completed study looked at 400 people with both heart disease and a mental health condition (like depression or anxiety). Researchers used questionnaires, blood tests, and imaging to find shared risk factors and biological markers. The goal was to better understand how these …

This study looked at 481 stroke patients who had a procedure to remove a blood clot from their brain. Researchers compared those who received general anesthesia (fully asleep) versus sedation (awake but relaxed). They tracked death rates and recovery to see if one method was bett…

This study looked at 455 stroke patients to see if a continuous finger blood pressure monitor (Clearsight) or standard arm cuff measurements better predict brain bleeding after clot removal. Each patient had both methods used within 24 hours after treatment. The goal was to see w…

This early study tested whether breathing short bursts of low oxygen (like being on a tall mountain) is safe for people who had a stroke. The idea is that this might trigger the brain to release proteins that help it recover. 16 stroke survivors took part, and the main goal was t…

This study looked at 79 people who had a stroke to see if levels of a protein called PrPC in their blood were linked to how severe the stroke was and how well they recovered. Researchers collected blood samples and checked patients' health 3 months later. No treatments were teste…

This study measured muscle loss (sarcopenia) in 80 stroke survivors using simple tests like grip strength, walking speed, and ultrasound. Researchers compared patients who had a stroke recently (post-acute care) with those who had one over a year ago. The goal was to see how age,…

This study tested whether a special type of MRI, called high-resolution vessel wall imaging, can help predict if a stroke will happen again in people with a narrowed brain artery. Researchers followed 74 patients who had a stroke or mini-stroke and received artery-opening treatme…

This study tested a program to help people with stroke or TIA transition from hospital to home. 213 participants received either the program or usual care. The program focused on improving communication, health literacy, and medication management. Researchers measured quality of …

This study tested whether a special MRI scan called IVIM can predict how well people recover three months after an acute ischemic stroke. Researchers added a two-minute scan to the standard MRI for 274 adults admitted with stroke. They then compared the scan results to the patien…

This study looked at 174 adults who had a stroke and were treated under general anesthesia. Researchers compared removing the breathing tube early versus later to see which approach leads to better functional recovery after 90 days. The goal is to find the best time to take patie…

This study examined 200 adults who had surgery to remove plaque from their carotid arteries. Researchers identified bacteria living inside the plaques and tracked whether certain types were linked to later strokes, re-narrowing of the artery, or death. The goal was to learn which…

This completed study looked at 26,000 patients who had outpatient procedures for blood vessel problems like peripheral artery disease, varicose veins, or dialysis access issues. The goal was to see how safe and effective these procedures are when done in an office-based angiosuit…

This study tested whether raising the legs (elevated leg positioning) is safe and practical for people who have had a moderate ischemic stroke. Fifty adults with moderate stroke symptoms were enrolled within 24 hours of symptom onset. The goal was to see if this simple, non-drug …

This study observed how breathing machines (mechanical ventilation) are used in 2,299 brain-injured patients in intensive care units worldwide. Researchers collected data on different ventilation strategies and their link to patient recovery. No new treatments were tested; the go…

This study looked at whether wearing an activity monitor (like a Fitbit) after heart surgery helps patients get moving sooner and return to their normal activity levels faster. Researchers tracked motivation, length of hospital stay, and readmission rates in 12 adults who had car…

This study tested whether telephone interviews after a stroke can help patients better understand and follow their medication plans. 54 adults who had an ischemic stroke and were returning home received a pharmaceutical interview before discharge, followed by phone calls at one w…

This study measured levels of a brain protein called BDNF in 50 stroke patients who received a clot-busting drug. Researchers wanted to see if BDNF levels rise after treatment and if they could help predict recovery of movement, thinking, and mood three months later. The goal is …

This study looked at 1499 people who had an acute ischemic stroke and got a chest CT within 24 hours. Researchers wanted to see if combining CT findings with clinical signs and inflammation markers could better predict who would develop pneumonia within a week. They built and tes…

This small pilot study explored whether advanced heart imaging can detect hidden strokes in people who have never had atrial fibrillation but are at high risk due to conditions like diabetes or heart failure. Researchers used brain MRIs to find silent, symptom-free strokes and li…

This study tested whether special communication training for pharmacists and general practitioners helps them involve older patients in decisions to stop or lower medications for heart disease and diabetes. Researchers enrolled 310 patients aged 75 and older who were taking certa…

This Phase 1 trial tested the safety of LT3001, a potential clot-busting drug for acute ischemic stroke, in 65 healthy adults. Participants received multiple doses of LT3001 alone or with common stroke medications like aspirin and clopidogrel. The goal was to check for side effec…

This study tested whether intensive treadmill training with a harness to support body weight can improve walking and balance in people who recently had a stroke. Forty participants in the subacute phase (2-6 weeks after stroke) completed a 3-week program. Researchers also measure…

This first-in-human study tested a new smart guidewire (Clotild®) in 45 stroke patients undergoing emergency clot removal. The wire helps guide the removal tool and also measures the clot's electrical properties to determine its composition. The main goal was to check safety, suc…

This study looked at over 2,400 stroke patients who received clot-busting drugs (alteplase or tenecteplase) within 4.5 hours of symptoms. Researchers wanted to see if adding Shuxuetong injection, a traditional Chinese medicine, could improve recovery and reduce disability. The go…

This study tested whether a theory-based motivational letter mailed six months in advance could increase attendance at a one-year post-cardiac rehabilitation check-up. Researchers compared 102 adults who received the letter to those who got usual care. The goal was to see if a si…

This study looked at how small blood vessels in the brain change after a stroke caused by small vessel disease. Researchers used a special 3D X-ray technique to take detailed pictures of these vessels. The goal was to learn more about the disease process, which could help doctors…

This study looked at 91 Chinese patients with atrial fibrillation who had a stroke while taking blood thinners (NOACs). The goal was to understand why these strokes happen and whether not taking the medication as prescribed played a role. Researchers hope this knowledge will help…

This study evaluated how aware caregivers are of secondary complications after a stroke, such as muscle stiffness, swallowing problems, and depression. Researchers surveyed 80 caregivers of stroke patients to see if education during rehabilitation improves their knowledge. The go…

This study measured the amount of common blood thinners (dabigatran, apixaban, and rivaroxaban) in the blood of 308 Chinese adults with atrial fibrillation who had been taking the medication for at least 3 months. The goal was to establish normal reference ranges for these drugs …

This study looked at 120 people who had an acute ischemic stroke to see if the types of bacteria in their gut were linked to how well they recovered. Researchers analyzed stool samples and brain scans, and tracked disability over 6 months. The goal was to understand the role of g…

This completed study looked at 213 people with acute ischemic stroke to see if combining brain scans with blood tests could better predict complications like brain swelling or bleeding. Researchers also used a mouse model to study how brain cells change after stroke. The goal is …

This study tested two heart monitoring methods in 516 people who had a transient ischemic attack (TIA or mini-stroke). The goal was to see which method better detects hidden atrial fibrillation, a heart rhythm problem that raises stroke risk. Participants received either a small …

This study looked at 126 people who recently had a stroke caused by a blocked blood vessel in the brain. Researchers wanted to find out how common fatigue is after a stroke and what factors might be linked to it, including any treatments given in the first days. Participants comp…

This study used artificial intelligence to learn the patterns of reduced blood flow to the brain during planned surgeries. 60 patients having carotid artery surgery or stroke clot removal were monitored with non-invasive devices. The goal was to teach AI to recognize these patter…

This completed study tested a program to help stroke survivors in rural Kentucky take their blood pressure medications as prescribed. Four participants received one-on-one education and tailored sessions from a pharmacy technician and community health worker. The goal was to see …

This study looked at 79 people with a rare type of stroke caused by calcified particles traveling to the brain. Researchers used CT scans to describe the size, location, and density of these particles, and compared patients' medical histories and risk factors. The goal was to bet…

This pilot study tested a wearable robotic exoskeleton called EksoNR in 5 people with stroke, spinal cord injury, cerebellar ataxia, or spastic paraplegia. The goal was to see if using the device for gait training in an outpatient setting is safe, tolerable, and feasible. Researc…

This study looked at 129 patients who had surgery to clear blocked neck arteries, a common cause of stroke. Doctors compared two surgical techniques—the eversion method and the conventional method—to see which had fewer complications like stroke or artery re-blockage within 30 da…

This study looked at whether planning, reminders, and small rewards can help older adults who had a mild or moderate traumatic brain injury (TBI) walk more. 57 participants wore a Fitbit and received weekly calls for 12 weeks. The goal was to see if these simple tools could incre…

This study looked at how different types of exercise (interval vs. continuous) and intensity levels (moderate vs. high) affect aerobic fitness and blood vessel health in people who have had a stroke. 59 participants used a seated stepper that moves both arms and legs. The goal wa…

This study looked at how well a daily low-dose aspirin works in people who have both immune thrombocytopenia (low platelets) and heart disease. Only 4 adults took part. Researchers measured platelet function after aspirin to see if the standard dose is enough to prevent blood clo…

This study tested whether a systematic phone call from a medical student, supervised by a general practitioner, could reduce hospitalizations in patients with chronic heart or mental health conditions during the COVID-19 lockdown in France. Over 22,000 patients aged 70 and older …

This study looked at 320 adults who had heart surgery to see how well two different risk scores (EuroSCORE-II and POSPOM) predict the chance of dying in the hospital. Researchers calculated each patient's scores before surgery and compared them to what actually happened. The goal…

This study looked at whether orienteering (a navigation-based walk) is as good as regular walking for heart rehab. 40 people with stable heart disease took part. Researchers measured heart rate and enjoyment during both activities. The goal was to see if orienteering could be a f…

This study tested whether emergency physicians can accurately predict stroke by interviewing witnesses who saw the symptoms start. Researchers asked 235 witnesses to describe what they observed, then compared the doctors' scores to brain scans. The goal was to see if this method …

This study looked at how well the ReVive™ SE device works to restore blood flow in the brain during a stroke. Only one patient took part, and the goal was to see if the device is useful in standard care. The main measure was how much blood flow returned after using the device.

This study looked at how much people who had a transient ischemic attack (TIA or mini-stroke) understand about their condition after being treated in the emergency room. About 100 adults in Lyon, France, answered a questionnaire to test their knowledge of symptoms, risk factors, …

This completed study looked at whether patients hospitalized for a heart attack, stroke, or other cardiovascular event received the right medications to prevent future problems. Researchers reviewed records of 129 patients to see if doctors prescribed cholesterol-lowering drugs a…

This study looked at how fast treadmill walking, with or without a small electrical stimulation to the ankle muscles, helps people who have had a stroke walk better. Fifty-five participants who were at least six months past their stroke took part. The goal was to understand the b…

This study tested two types of non-invasive brain stimulation (called paired associative stimulation) to see if they could help improve hand movement in people who had a stroke. 81 participants (60 stroke survivors and 24 healthy volunteers) took part. The main goal was to unders…

This study looked at brain MRI scans of 122 stroke patients to see if those with a blood clot in the heart (intracardiac thrombus) had different patterns of brain damage compared to those with atrial fibrillation. Researchers analyzed the location, size, and number of stroke lesi…

This study tested a wearable sensor system (IMAS) to measure arm movement in 30 people who recently had a stroke. The goal was to see if the sensors could accurately predict how well arm function would recover. Researchers used motion data to build a model and compared it to stan…

This study tested whether an artificial intelligence (AI) tool called qER 2.0 EU helps doctors and other health professionals read head CT scans more accurately and quickly. Thirty-three readers, including radiologists, emergency doctors, and radiographers, reviewed 150 scans wit…

This completed study followed 633 stroke or TIA survivors in France to understand why some stop taking their secondary prevention medications. Researchers looked at factors like age, beliefs about medicine, and healthcare access. The goal is to improve long-term adherence and pre…

This study looked at how well people think and remember after surgery to clear a blocked neck artery (carotid endarterectomy). About 800 patients took brain tests before and after surgery, and their results were compared to people having spine surgery. The goal was to find out ho…

This study reviewed medical records of 70 children under 18 who received clot-busting drugs or mechanical clot removal for a stroke. Researchers measured how quickly treatment was given and looked for side effects like bleeding. The goal is to better understand the safety and tim…

This study tested whether an artificial intelligence system that gives doctors feedback could improve the quality of emergency stroke treatment. Over 1,200 stroke patients were involved. The AI system aimed to help doctors make better decisions during a procedure to remove blood …

This completed pilot study tested whether giving a daily multi-nutrient drink to people who recently had an ischemic stroke is practical and acceptable. Twenty-four adults were split into two groups: one received the drink plus standard care, the other standard care alone. The ma…

This study tested an indoor air pollution intervention called AIRWISE in 20 adults aged 55 and older with heart disease. Participants received personal air cleaners, a color-changing air quality monitor, and educational materials. The goal was to see if they would use these tools…

This study created a database of information from 105 stroke patients who had a procedure to remove a large blood clot from the brain. Doctors used a special wire to help guide a tube to the clot. The goal was to see if the wire alone could get the tube to the right spot. This wa…

This study tested whether a mild electrical pulse on the ear (vagus nerve stimulation) can reduce inflammation after a stroke. Forty adults with a recent stroke received either standard care or standard care plus the ear stimulation. Researchers measured changes in blood markers …

This completed study tested whether healthcare claims data can predict the results of a major heart trial (SURPASS-CVOT) comparing two diabetes drugs, tirzepatide and dulaglutide. Researchers analyzed records from over 44,000 people with type 2 diabetes and heart disease to see i…

This study followed 364 adults with severe stroke who needed a breathing machine in the ICU. Researchers measured their recovery and disability levels at 3 months and 1 year after ICU admission. The goal was to better understand what happens to these patients over time, not to te…

This study looked at how often people have vision problems after a stroke. Researchers followed 127 stroke patients for 3 months, testing their eyesight and comparing results with brain scans. The goal was to find out how common these issues are and whether a simple vision screen…

This study looked at whether measuring the optic nerve sheath with ultrasound can help identify which side of the brain is affected in suspected stroke patients. Researchers measured the nerve sheath in 19 adults in the emergency department and compared it to their physical exam …

This study gathered brain monitoring data from 162 patients with serious brain injuries, such as traumatic brain injury or stroke. Using a noninvasive ultrasound device, researchers recorded blood flow signals to build a database. The goal is to develop algorithms that could one …

This study looked at 55 stroke survivors to see if arm function in the first days after stroke can predict trunk (core) recovery weeks later. Researchers measured trunk impairment and arm skills using standard tests. The goal is to find simple early clues that help therapists pla…

This study tested whether a special MRI contrast agent called ferumoxytol can detect inflammation in brain arteries of people who recently had a stroke. Researchers compared it to standard gadolinium contrast in 30 participants with narrowed brain arteries. The goal was to see if…

This study looked at two ways to assign care coordinators to older adults (65+) with heart disease or risk factors. One method used patients' own reports of difficulty coordinating care, while the other used usual triggers like hospital discharge. The goal was to see which approa…

This completed study in 600 stroke patients in the Middle East looked at what factors might predict different types of brain bleeding after treatment with the clot-busting drug alteplase. Researchers analyzed patient characteristics, how quickly the drug was given, and stroke ris…

This study looked at 400 stroke patients who had a clot-removal procedure (thrombectomy) within 24 hours of symptoms. Researchers wanted to find out which factors helped patients recover well, such as being able to walk independently. The goal is to better predict who benefits fr…

This study used advanced MRI scans to look at how water and brain chemicals move in the brain after a stroke. Researchers scanned 24 stroke patients and 24 healthy volunteers to track changes over three months. The goal was to learn more about how brain cells are affected, which …

This completed study looked at how the brain adapts eye movements and how that relates to visual perception and attention. Researchers studied 24 people, including healthy adults and those with cerebellar disease. Participants performed specific eye movement tasks while researche…