Could a simple leg cuff cut stroke risk? new study tests EECP therapy

NCT ID NCT03921827

Completed Disease control Sponsor: National University of Singapore Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether Enhanced External Counterpulsation (EECP) therapy, a non-invasive treatment using leg cuffs to boost blood flow, can improve brain circulation in people with severe narrowing of key brain arteries. The 130 participants had recently experienced a stroke or mini-stroke and had poor blood flow reserve. The goal was to see if EECP could increase blood flow reserve by at least 4% and reduce the risk of another stroke.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Enhanced External Counterpulsation (EECP) therapy
What this could lead to: If it works, this could offer a non-invasive way to improve brain blood flow and lower the chance of another stroke in people with severe artery narrowing.
What could go wrong: This is a completed early-stage trial with 130 participants, so results may not apply to everyone. The therapy may not improve blood flow enough or reduce stroke risk as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cerebral artery stenosis ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ISCHEMIC STROKE

Contacts and locations

Locations

National University Hospital

Singapore, 119228, Singapore

More trials for these conditions

Other studies related to the condition(s) this trial covers.