New stroke drug LT3001 passes first safety check in healthy volunteers
NCT ID NCT04809818
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 1 trial tested the safety of LT3001, a potential clot-busting drug for acute ischemic stroke, in 65 healthy adults. Participants received multiple doses of LT3001 alone or with common stroke medications like aspirin and clopidogrel. The goal was to check for side effects and how the drug interacts with other treatments, not to measure effectiveness against stroke.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
LT3001 injection
What this could lead to
If successful, this could pave the way for a new stroke treatment that dissolves clots and may be safer when used with other medications.
What could go wrong
This is an early Phase 1 study in healthy volunteers, not stroke patients. It only tests safety and drug interactions, not whether LT3001 actually treats strokes.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- THUNDER Stroke Study: Penumbra System with Thund NCT05437055
- Stroke Alarm Efficacy Trial (NCT06315192)
- IMPROVE-II: FAST Model for Stroke Reperfusion (NCT06330051)
- Virtual Reality Rehab for Stroke Recovery - NCT07674329
- Endovascular Therapy for Basilar Artery Stroke (NCT07672795)
- Oropharyngeal Suction Tube for Stroke Pneumonia NCT07647666
Contacts and locations
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Locations
-
Lumosa Phase 1 Unit
Cypress, California, 90630, United States