New stroke drug shows promise in early trial

NCT ID NCT06202378

Completed Disease control Sponsor: Shanghai Hutchison Pharmaceuticals Limited Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new drug called SHPL-49 in 270 people who had an acute ischemic stroke. Participants received either the drug or a placebo as an IV infusion twice daily for 7 days. The goal was to see if the drug helps improve recovery and is safe to use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: SHPL-49 injection
What this could lead to: If successful, this could point toward a new treatment to improve recovery after a stroke.
What could go wrong: This is a Phase 2 trial, so results are still early. The treatment may not prove effective or safe in larger studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE ISCHEMIC STROKE

Contacts and locations

Locations

Beijing Tiantan Hosptial，Capital Medical University

Beijing, Beijing Municipality, 100070, China
Beipiao Central Hospital

Beipiao, Liaoning, 122199, China
General Hospital of Pingmei Shenma Group

Pingdingshan, Henan, 467099, China
Hengshui People's Hospital

Hengshui, Hebei, 053099, China
Keshiketeng Banner Traditional Chinese Medicine and Mongolian Medicine Hospital

Chifeng, Inner Mongolia, 025350, China
Linfen Central Hospital

Linfen, Shanxi, 041000, China
Linfen People's Hospital

Linfen, Shanxi, 041000, China
Linyi People's Hospital

Linyi, Shandong, 276100, China
Nanshi Hospital of Nanyang

Nanyang, Henan, 473010, China
Shenyang Medical College Affiliated Central Hospital

Shenyang, Liaoning, 110024, China
Sinopharm Tongmei General Hospital

Datong, Shanxi, 037001, China
Tangshan Workers' Hospital

Tangshan, Hebei, 063099, China
The First Hospital of Jilin University

Changchun, Jilin, 130021, China
The First People's Hospital of Shenyang

Shenyang, Liaoning, 110041, China
The First People's Hospital of Tancheng

Linyi, Shandong, 276100, China
Yuebei People's Hospital

Shaoguan, Guangdong, 512026, China

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