New stroke drug shows promise in early trial

NCT ID NCT06202378

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new drug called SHPL-49 in 270 people who had an acute ischemic stroke. Participants received either the drug or a placebo as an IV infusion twice daily for 7 days. The goal was to see if the drug helps improve recovery and is safe to use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SHPL-49 injection

What this could lead to

If successful, this could point toward a new treatment to improve recovery after a stroke.

What could go wrong

This is a Phase 2 trial, so results are still early. The treatment may not prove effective or safe in larger studies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Tiantan Hosptial,Capital Medical University

    Beijing, Beijing Municipality, 100070, China

  • Beipiao Central Hospital

    Beipiao, Liaoning, 122199, China

  • General Hospital of Pingmei Shenma Group

    Pingdingshan, Henan, 467099, China

  • Hengshui People's Hospital

    Hengshui, Hebei, 053099, China

  • Keshiketeng Banner Traditional Chinese Medicine and Mongolian Medicine Hospital

    Chifeng, Inner Mongolia, 025350, China

  • Linfen Central Hospital

    Linfen, Shanxi, 041000, China

  • Linfen People's Hospital

    Linfen, Shanxi, 041000, China

  • Linyi People's Hospital

    Linyi, Shandong, 276100, China

  • Nanshi Hospital of Nanyang

    Nanyang, Henan, 473010, China

  • Shenyang Medical College Affiliated Central Hospital

    Shenyang, Liaoning, 110024, China

  • Sinopharm Tongmei General Hospital

    Datong, Shanxi, 037001, China

  • Tangshan Workers' Hospital

    Tangshan, Hebei, 063099, China

  • The First Hospital of Jilin University

    Changchun, Jilin, 130021, China

  • The First People's Hospital of Shenyang

    Shenyang, Liaoning, 110041, China

  • The First People's Hospital of Tancheng

    Linyi, Shandong, 276100, China

  • Yuebei People's Hospital

    Shaoguan, Guangdong, 512026, China