New device aims to clear stroke clots faster and safer

NCT ID NCT05714501

Completed Disease control Sponsor: Perfuze Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new device called the Millipede System in 246 stroke patients with large blood clots in the brain. The device is designed to remove clots and restore blood flow. Researchers measured how often blood flow was successfully restored and tracked any side effects. The goal was to see if the device is safe and effective for treating acute ischemic stroke.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Millipede System (a medical device used to remove blood clots from brain arteries)

What this could lead to

If successful, this device could offer a more effective and safer way to restore blood flow in stroke patients, potentially improving recovery and reducing disability.

What could go wrong

This is a completed early-stage study without a control group, so results may not prove superiority over existing treatments. Risks include bleeding or other complications from the procedure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ischemic stroke large artery stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE ISCHEMIC STROKE

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

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Locations

Baptist Health Research Institute

Jacksonville, Florida, 32207, United States
CHRU Strasbourg

Strasbourg, 67200, France
CHRU de Nancy

Nancy, France
CHU Bordeaux

Bordeaux, 33076, France
CHU Montpellier

Montpellier, France
CHU de Nantes - HGRL

Nantes, 44093, France
Emory

Atlanta, Georgia, 30322, United States
Hospital Universitario La Paz

Madrid, 28046, Spain
Mercy Health

Toledo, Ohio, 43608, United States
Oregon Health & Science University (OHSU)

Portland, Oregon, 97239, United States
ProMedica Toledo Hospital

Toledo, Ohio, 43606, United States
Semmes Murphey Foundation

Memphis, Tennessee, 38120, United States
Stony Brook University Hospital

Stony Brook, New York, 11794, United States
Tampa General Hosital

Tampa, Florida, 33612, United States
Toulouse University Hospital -CHU Purpan

Toulouse, France
UT Houston

Houston, Texas, 77225, United States
University Of Rochester Medical Center (URMC)

Rochester, New York, 14620, United States
University of Chicago

Chicago, Illinois, 60637, United States
University of Pittsburgh Medical Center (UPMC)

Pittsburgh, Pennsylvania, 15213, United States
University of Toledo

Toledo, Ohio, 43614, United States
Vall d'Hebron

Barcelona, Spain
Valley Baptist Medical Center

Harlingen, Texas, 78550, United States
Yale University Hospital

New Haven, Connecticut, 06510, United States