Stroke study: can a quick blood flow pause boost brain recovery?

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * The patient is ≥ 18 years of age. * The patient must have symptoms consistent with AIS (i.e. face drooping, arm weakness, speech difficulty, etc.) , with symptoms severity of baseline NIHSS ≥ 6 and beginning less than 24 hours prior to presentation at hospital. * Pre-stroke mRS ≤ 2. * Baseline ASPECTS ≥ 6. * Unilateral middle cerebral artery occlusion, and/or internal carotid artery occlusion. * The patient is eligible for EVT. * Successful recanalization achieved through EVT (eTICI 2b-3). * The patient is willing to provide written informed consent to participate in this clinical trial. Exclusion Criteria: * The interventionalist deems the study device unable to reach the target site. * Adverse events related to thrombectomy, such as contrast extravasation, vascular rupture/perforation, dissection, or embolization to a new territory, detected on post-thrombectomy angiography. * Stent placement performed in the M1 segment of the middle cerebral artery or the terminal segment of the internal carotid artery during thrombectomy. * Angioplasty of more than two cycles of balloon inflation/deflation. * The patient is experiencing cardiogenic shock, systolic blood pressure \[SBP\] \<100 mmHg, HR\>100 bpm and arterial oxygen saturation (pulse oximetry) \<92% without additional oxygen. * The patient has known history of Congestive Heart Failure, hepatic failure, end-stage kidney disease or severe renal failure (clearance \< 30ml/min/1.73m²). * The patient is febrile (temperature \> 37.5 °C) or has experienced an infection with fever in the last 5 days. * The patient has a known hypersensitivity or contraindication to aspirin, heparin, Clopidogrel, tirofiban, or sensitivity to contrast media, which cannot be adequately pre-medicated. * The patient has a known history of bleeding diathesis, coagulopathy, cryoglobulinemia, sickle cell anemia, or will refuse blood transfusions. * The patient has a pre-AIS life expectancy of \<1 year due to underlying medical conditions or pre-existing co-morbidities. * The patient is currently enrolled in another investigational drug or device trial. * The patient is apprehensive about or unwilling to undergo the required MRI imaging at follow-up, has a documented or suspected diagnosis of claustrophobia, or has Gadolinium allergy. * The patient is a female who is known to be pregnant. * Other conditions deemed unsuitable for inclusion by the investigator.