Stroke drug tirofiban may boost recovery after clot removal

NCT ID NCT06265051

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether giving the blood-thinning drug tirofiban after mechanical clot removal improves outcomes for people with severe stroke. Over 1,300 participants were randomly assigned to receive tirofiban or a placebo. The goal was to see if more patients could live independently at 90 days without increasing dangerous bleeding.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Tirofiban (a blood-thinning drug given intravenously)
What this could lead to
If successful, this could provide a proven way to improve recovery and reduce disability after a severe stroke.
What could go wrong
This is a mid-stage trial; results may not confirm benefit, and tirofiban can increase bleeding risk, including in the brain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, 450001, China

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