Blood test could help paramedics spot severe strokes before the hospital

NCT ID NCT04726839

Completed Diagnosis Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked at whether a panel of blood biomarkers can quickly identify stroke patients who have a large vessel occlusion (a major blockage) and would benefit from a specialized clot-removal procedure. Researchers enrolled nearly 3,900 adults with stroke symptoms and tested their blood in the ambulance or emergency room. The goal is to help paramedics decide which hospital to take a patient to, avoiding delays that can worsen outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: blood biomarker panel
What this could lead to: If successful, this blood test could help paramedics quickly identify stroke patients who need a specialized clot-removal procedure, getting them to the right hospital faster and improving outcomes.
What could go wrong: This is a completed study analyzing blood samples, not a treatment trial. The biomarker panel may not be accurate enough in real-world ambulance settings, and further validation is needed before it can be used routinely.

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Conditions

The condition(s) this trial relates to.

cerebral artery occlusion ischemic stroke large artery stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LARGE VESSEL OCCLUSION STROKE, ISCHEMIC

Contacts and locations

Locations

Department Neurology Caen Hospital

Caen, France
Hospital Foch

Suresnes, France
Lariboisière

Paris, 75010, France
Rothschild Foundation Hospital

Paris, France

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