ALZHEIMER DISEASE
Clinical trials for ALZHEIMER DISEASE explained in plain language.
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Scientists test Brain-Boosting drug duo to slow early dementia
Disease control Recruiting nowThis study is testing whether combining two types of drugs works better than one to slow cognitive decline in early Alzheimer's disease or mild cognitive impairment. Researchers will give 80 participants a drug that affects brain signaling (an NMDA-enhancing agent) plus an antiox…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: Chang Gung Memorial Hospital • Aim: Disease control
Last updated Apr 01, 2026 21:26 UTC
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Can dancing help protect aging brains from Alzheimer's?
Disease control Recruiting nowThis study is testing whether two different exercise programs—cardio-dance fitness versus strength, flexibility, and balance training—can improve brain health and reduce Alzheimer's disease risk in older African Americans. Researchers will enroll 280 sedentary adults aged 60+ to …
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Apr 01, 2026 21:26 UTC
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Gut health formula tested for Alzheimer's relief
Disease control Recruiting nowThis small pilot study is testing whether a new probiotic formula (SCV09) can improve behavioral symptoms and daily functioning in people with Alzheimer's disease. Researchers are exploring the connection between gut health and brain function. The study will enroll 30 participant…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated Apr 01, 2026 21:26 UTC
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Brain drainage surgery shows fleeting hope for Alzheimer's patients
Disease control Recruiting nowThis study is testing whether a small neck surgery can temporarily improve thinking and daily function in people with Alzheimer's disease. The surgery aims to help drain fluid from the brain. Researchers will compare the real surgery to a sham procedure in 50 patients to see if t…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: General Hospital of Shenyang Military Region • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Alzheimer's patients continue experimental treatment in Long-Term safety study
Disease control Recruiting nowThis study continues testing an experimental treatment called SNK01 for Alzheimer's disease to check its long-term safety and see if it might help with thinking and memory. It's for 30 people who already completed an earlier study of the same treatment. Participants receive SNK01…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: NKGen Biotech, Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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New drug trial aims to put the brakes on Alzheimer's
Disease control Recruiting nowThis study is testing an oral drug called Senicapoc to see if it can slow down the progression of Alzheimer's disease in people with early memory problems. About 55 participants will take either the drug or a placebo daily for one year. Researchers will measure changes in memory,…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: University of California, Davis • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Major trial tests if Vitamin-Like supplements can slow Alzheimer's decline
Disease control Recruiting nowThis study is testing whether a specific blend of dietary supplements can help improve brain function in people with Alzheimer's disease. About 845 participants will take either the supplement capsules or a placebo twice a day for 26 weeks. Researchers will measure changes in mem…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE3 • Sponsor: ScandiBio Therapeutics AB • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Brain zap trial aims to slow Alzheimer's decline
Disease control Recruiting nowThis study is testing whether a non-invasive magnetic brain stimulation treatment can help people with mild Alzheimer's disease. Researchers will target a part of the brain called the cerebellum to see if it improves memory, thinking skills, and the ability to perform daily activ…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Xijing Hospital • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Brain zaps aim to slow Alzheimer's decline
Disease control Recruiting nowThis study tests a new, non-invasive brain stimulation treatment for people with mild Alzheimer's disease. Researchers will use a combination of magnetic and electrical pulses, targeted to specific brain networks, to try to slow the progression of memory and thinking problems. Th…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: I.R.C.C.S. Fondazione Santa Lucia • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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VA tests virtual system to speed Alzheimer's care for veterans
Disease control Recruiting nowThis study is testing a new virtual care program designed to help veterans with early Alzheimer's disease or memory problems get diagnosed and access new treatments more quickly. The program uses telehealth visits, advanced brain scans, and streamlined paperwork to reduce wait ti…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: VA Pittsburgh Healthcare System • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Shining a light on Alzheimer's: new combo therapy trial
Disease control Recruiting nowThis study is testing whether adding a special near-infrared light therapy to the approved Alzheimer's drug lecanemab is safe and more effective at controlling the disease. It will involve 20 people with mild Alzheimer's. For 16 weeks, half will get the real light therapy with th…
Matched conditions: ALZHEIMER DISEASE
Phase: EARLY_PHASE1 • Sponsor: Xuanwu Hospital, Beijing • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Race against time: can new Alzheimer's drug delay need for care?
Disease control Recruiting nowThis large, real-world study aims to see if adding the drug donanemab to usual care helps people with early Alzheimer's disease maintain their independence longer than usual care alone. It will follow about 6,250 participants for over five years, tracking how long they can live a…
Matched conditions: ALZHEIMER DISEASE
Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New shot in the arm for Alzheimer's? early drug trial seeks answers
Disease control Recruiting nowThis early-stage study is testing a new drug called ARO-MAPT-SC to see if it is safe and how it behaves in the body. It will involve both healthy volunteers and people with early Alzheimer's disease. The main goal is to find a safe dose and understand the drug's effects before te…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Arrowhead Pharmaceuticals • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Vitamin B1 derivative trial aims to put brakes on Alzheimer's decline
Disease control Recruiting nowThis study is testing whether a form of vitamin B1 called benfotiamine can slow down the worsening of memory and daily function in people with early Alzheimer's disease. Over 400 participants will take either the study drug or a placebo for 18 months to see if it is safe and effe…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: Alzheimer's Disease Cooperative Study (ADCS) • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Magnetic pulses to the brain: new hope for Alzheimer's memory?
Disease control Recruiting nowThis UCLA study is testing whether a non-invasive brain stimulation technique can help improve memory in people with mild-to-moderate Alzheimer's disease. Researchers will use a device that delivers magnetic pulses to a specific brain area to see if it's safe, tolerable, and show…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE1, PHASE2 • Sponsor: University of California, Los Angeles • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Brain injection trial aims to slow Alzheimer's by targeting toxic protein
Disease control Recruiting nowThis early-stage study is testing whether a new drug called NIO752 can reduce the brain's production of tau protein, which forms toxic tangles in Alzheimer's disease. Researchers will give the drug via spinal injection to 10 participants with mild to moderate Alzheimer's and meas…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE1 • Sponsor: University College, London • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Sound waves used to crack open Brain's shield in Alzheimer's fight
Disease control Recruiting nowThis study is testing whether a focused ultrasound device can safely and temporarily open the blood-brain barrier in people with Alzheimer's disease. The goal is to see if this opening could allow future treatments to better reach the brain. Up to 30 participants will receive thr…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Could an MS pill slow Alzheimer's brain shrinkage?
Disease control Recruiting nowThis study is testing whether a drug called siponimod, already approved for multiple sclerosis, can slow the progression of mild Alzheimer's disease. About 105 participants will take either the drug or a placebo for one year, followed by a six-month observation period. The main g…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: St. Joseph's Hospital and Medical Center, Phoenix • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Can nightly fasting slow Alzheimer's? new study investigates
Disease control Recruiting nowThis study is testing whether restricting eating to a 10-hour window each day (fasting for 14 hours overnight) can help slow cognitive decline in people with mild cognitive impairment or early Alzheimer's disease. Researchers will enroll 60 older adults to follow this eating patt…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE1 • Sponsor: University of California, San Diego • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Major trial tests new drug to slow Alzheimer's progression
Disease control Recruiting nowThis study is testing whether the drug donanemab is safe and effective at slowing the progression of early Alzheimer's disease. It will involve about 1,500 people who have mild memory problems and confirmed Alzheimer's-related brain changes. Participants will receive either the d…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Inner-Ear therapy trial aims to stop Alzheimer's patients from falling
Disease control Recruiting nowThis study is testing whether a special balance therapy can help prevent falls in people with mild-to-moderate Alzheimer's disease. Researchers will work with 100 participants who have both Alzheimer's and inner-ear balance problems. The therapy involves weekly sessions and daily…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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Zapping the brain to fight Alzheimer's memory loss
Disease control Recruiting nowThis study is testing if a gentle, non-invasive electrical stimulation to the brain can help improve memory in people with Alzheimer's disease. Researchers believe memory problems may be linked to poor coordination between different brain areas, and this stimulation aims to help …
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Boston University Charles River Campus • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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Migraine drug repurposed in bold hunt for Alzheimer's treatment
Disease control Recruiting nowThis small, early-stage study is testing whether a drug called galcanezumab, currently used for migraines, can help people with mild-to-moderate Alzheimer's disease. Ten participants will receive injections of the drug every four weeks for six months. Researchers will measure cha…
Matched conditions: ALZHEIMER DISEASE
Phase: EARLY_PHASE1 • Sponsor: Xuanwu Hospital, Beijing • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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New program aims to curb risky antibiotic overuse in dementia care
Disease control Recruiting nowThis study is testing a new program in nursing homes to improve how suspected infections are managed in residents with dementia. It aims to see if the program can safely reduce the use of antibiotics and avoid stressful hospital trips and tests. The study will involve about 750 r…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Hebrew SeniorLife • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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At-Home brain zaps tested to slow dementia decline
Disease control Recruiting nowThis study is testing whether a caregiver can safely use a home-based, non-invasive brain stimulation device to help improve memory, thinking, and walking in older adults with mild dementia or memory loss. Participants and their caregivers will be trained to use the device at hom…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Hebrew SeniorLife • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Common pill shows promise in early Alzheimer's fight
Disease control Recruiting nowThis study is testing if a safe, existing water pill called bumetanide might help control Alzheimer's disease. It will check the pill's safety and see if it improves thinking skills in 40 people with early Alzheimer's. The research is based on promising data suggesting the drug c…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: Stanford University • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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Tracking a new Alzheimer's drug: does it help and is it safe?
Disease control Recruiting nowThis study aims to closely watch 120 people with early Alzheimer's disease who are taking the drug lecanemab. Researchers will track changes in their brain scans, memory, thinking, and daily life over 18 months to see how well the drug works and monitor for any side effects. The …
Matched conditions: ALZHEIMER DISEASE
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated Mar 19, 2026 14:55 UTC
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Could a transplant drug hold the key to slowing Alzheimer's?
Disease control Recruiting nowThis study is testing whether a drug called rapamycin, taken daily for a year, is safe and might help slow down memory and thinking problems in older adults with early-stage Alzheimer's disease or mild cognitive impairment. Researchers will enroll 40 participants to measure chang…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC
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Could a bone marrow drug slow Alzheimer's?
Disease control Recruiting nowResearchers are testing if a drug called sargramostim, already approved for other uses, is safe and might help people with mild-to-moderate Alzheimer's disease. The 6-month study with 42 participants will check if the drug can slow or stop cognitive decline and improve daily func…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC
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New Alzheimer's pill enters human testing phase
Disease control Recruiting nowThis is the first human study of a new capsule called J4 being developed for Alzheimer's disease. Researchers are testing it in 76 healthy adults to check if it's safe and to understand how the body processes it. The study will give participants either the drug or a placebo in in…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE1 • Sponsor: Academia Sinica, Taiwan • Aim: Disease control
Last updated Mar 17, 2026 12:55 UTC
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Spinal injection trial tests new hope for Alzheimer's
Disease control Recruiting nowThis early-stage study is testing the safety of a new drug called LY3954068 for people with early Alzheimer's symptoms. The drug is given as an injection into the spinal fluid. Researchers will check how the body processes the drug and look for any side effects in 48 participants…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE1 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Mar 17, 2026 12:55 UTC
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German doctors test gentle brain pulses to slow Alzheimer's decline
Disease control Recruiting nowThis German study is checking the safety of a non-invasive brain stimulation treatment called Transcranial Pulse Wave Stimulation (TPS) for people with Alzheimer's disease. It will follow 100 patients to watch for any side effects and see if the treatment helps with memory, mood,…
Matched conditions: ALZHEIMER DISEASE
Sponsor: Heinrich-Heine University, Duesseldorf • Aim: Disease control
Last updated Mar 16, 2026 15:26 UTC
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Surgeons try neck bypass to drain brain toxins in Alzheimer's patients
Disease control Recruiting nowThis study is testing a new surgical procedure for people with mild to moderate Alzheimer's disease. Doctors will perform a neck surgery to create a bypass, aiming to help the brain drain away harmful proteins thought to cause the disease. The main goal is to check if the surgery…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Vincent Tay Khwee Soon • Aim: Disease control
Last updated Mar 16, 2026 15:25 UTC
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Ancient needles meet modern medicine: can acupuncture slow Alzheimer's?
Disease control Recruiting nowThis study is testing whether adding acupuncture to the standard Alzheimer's medication donepezil can better help patients with mild to moderate symptoms. It will involve 180 people who will either receive the medication alone or the medication plus acupuncture three times a week…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Jian Pei,MD • Aim: Disease control
Last updated Mar 16, 2026 15:23 UTC
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Common seizure drug could be key to fighting Alzheimer's in down syndrome
Disease control Recruiting nowThis study is testing whether a medication called levetiracetam, commonly used for seizures, can prevent epileptic seizures in adults with Down syndrome who also have Alzheimer's disease. Researchers also want to see if the drug can slow down the brain changes and memory loss lin…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE3 • Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau • Aim: Disease control
Last updated Mar 16, 2026 15:23 UTC
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Could a common sleep pill slow down Alzheimer's?
Disease control Recruiting nowThis study is testing whether a prescription sleep aid called lemborexant can reduce levels of proteins linked to Alzheimer's disease in the body. It will involve about 200 older adults who have early signs of Alzheimer's but no memory problems yet. Researchers will measure prote…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Mar 13, 2026 15:05 UTC
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Sound waves aimed at the brain to fight Alzheimer's
Disease control Recruiting nowThis early study is testing whether a gentle, focused ultrasound device can safely be used to stimulate the brain in people with early memory loss due to Alzheimer's disease. The goal is to see if this non-invasive approach can improve brain function and slow decline. Researchers…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Ali Rezai • Aim: Disease control
Last updated Mar 12, 2026 13:52 UTC
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Magnetic pulses to the brain tested to help fend off memory loss
Disease control Recruiting nowThis study is testing whether a non-invasive brain stimulation technique, combined with memory training, can help improve thinking skills in older adults who are worried about their memory and have a family history of Alzheimer's disease. About 30 participants will receive either…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Rotman Research Institute at Baycrest • Aim: Disease control
Last updated Mar 05, 2026 14:00 UTC
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First human tests begin for new Alzheimer's treatment
Disease control Recruiting nowThis early-stage study is testing the safety and side effects of a new Alzheimer's drug called LY4006895. Researchers will give the drug to healthy volunteers and people with early memory problems from Alzheimer's disease to see how their bodies handle it. The study will measure …
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE1 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Feb 27, 2026 15:17 UTC
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New brain scan battle: which test spots Alzheimer's sooner?
Diagnosis Recruiting nowThis study aims to determine whether a newer type of brain scan (tau-PET) is more helpful for doctors than the current standard scan (amyloid-PET) when diagnosing Alzheimer's disease. It will involve 120 people aged 50-85 who have mild memory problems or early-stage dementia. Res…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: University Hospital, Geneva • Aim: Diagnosis
Last updated Apr 01, 2026 14:41 UTC
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Hunt for Alzheimer's early warning signs launches in china
Diagnosis Recruiting nowThis large study aims to find early signs of Alzheimer's disease by looking at blood, genes, and brain scans. Researchers will follow 6,000 older adults in China for five years to identify markers that can spot the disease sooner. The goal is to create a test kit for early diagno…
Matched conditions: ALZHEIMER DISEASE
Sponsor: Capital Medical University • Aim: Diagnosis
Last updated Mar 31, 2026 12:12 UTC
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New iPad test aims to catch dementia earlier in underserved communities
Diagnosis Recruiting nowThis study is testing a new, brief iPad-based tool called MyCog to help primary care doctors detect early signs of memory loss and dementia more effectively. It focuses on helping older adults from Black, Hispanic/Latino, and low-income communities who often face delays in diagno…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Northwestern University • Aim: Diagnosis
Last updated Mar 31, 2026 12:11 UTC
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Could an eye scan spot Alzheimer's?
Diagnosis Recruiting nowThis study is testing a new eye scan to see if it can detect signs of Alzheimer's disease in the retina. Researchers will give a single injection of a special dye (AMDX-2011P) to 25 people with confirmed Alzheimer's and then take detailed pictures of their eyes. The main goals ar…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: Amydis Inc. • Aim: Diagnosis
Last updated Mar 30, 2026 14:32 UTC
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Could a simple tear test spot Alzheimer's?
Diagnosis Recruiting nowThis study aims to find a new, easier way to diagnose Alzheimer's disease. Researchers will collect small tear samples from 90 people, including those with Alzheimer's and healthy volunteers. They will check if certain proteins and other substances in tears can reliably indicate …
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: University Hospital, Tours • Aim: Diagnosis
Last updated Mar 30, 2026 14:27 UTC
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New Brain-Scan platform aims to spot Alzheimer's years earlier
Diagnosis Recruiting nowThis study is testing a new digital platform designed to detect very early signs of Alzheimer's disease. Researchers will use non-invasive tools like brain wave monitors and eye-tracking devices on 100 participants, some with mild memory concerns and some healthy, over 12 months.…
Matched conditions: ALZHEIMER DISEASE
Sponsor: IRCCS San Raffaele • Aim: Diagnosis
Last updated Mar 25, 2026 14:07 UTC
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Groundbreaking scan aims to spot Alzheimer's tau in living patients
Diagnosis Recruiting nowThis study is testing a new type of brain scan (called [18F]PI-2620 PET imaging) to see how accurately it can detect the tau protein linked to Alzheimer's disease in people while they are alive. It will enroll about 200 people, including those with Alzheimer's and healthy control…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE3 • Sponsor: Life Molecular Imaging Ltd • Aim: Diagnosis
Last updated Mar 23, 2026 15:16 UTC
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Could your phone know you have Alzheimer's before you do?
Diagnosis Recruiting nowThis study is exploring whether changes in how people use their smartphones could serve as an early warning sign for Alzheimer's disease. Researchers will collect three months of smartphone data from 90 people: some with memory complaints, some with mild cognitive decline, and so…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Poitiers University Hospital • Aim: Diagnosis
Last updated Mar 23, 2026 15:15 UTC
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Simple blood test could spot hidden Alzheimer's in hospital patients
Diagnosis Recruiting nowThis study is testing a blood test to see if it can help doctors find Alzheimer's disease earlier in people who are hospitalized for sudden confusion or memory problems. Researchers will enroll 30 hospitalized patients aged 60-90 who have no prior dementia diagnosis. The main goa…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Covenant Health, US • Aim: Diagnosis
Last updated Mar 18, 2026 18:25 UTC
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Can a simple dietary oil help shield the aging brain?
Prevention Recruiting nowThis study is testing whether a daily supplement made from flaxseed oil (a source of alpha-linolenic acid, or ALA) can help protect brain health and slow memory decline. It is for adults aged 60+ who have mild memory problems and carry a specific gene (APOE4) linked to higher Alz…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: Michal Schnaider Beeri, Ph.D. • Aim: Prevention
Last updated Apr 01, 2026 21:26 UTC
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Can a good Night's sleep stop Alzheimer's before it starts?
Prevention Recruiting nowThis study is testing whether a prescription sleep medication called suvorexant can slow down the buildup of a harmful protein in the brain that is linked to Alzheimer's disease. Researchers will enroll 200 healthy adults aged 65 and older who have normal memory. The main goal is…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Prevention
Last updated Mar 30, 2026 14:34 UTC
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Family power: new program aims to stop hospital confusion in elders
Prevention Recruiting nowThis study tests if involving family members in a proven hospital care program is better at preventing delirium (sudden, severe confusion) in older patients. It will compare the standard Hospital Elder Life Program (HELP) with a new version that trains and includes family caregiv…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated Mar 30, 2026 14:29 UTC
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New study: shedding pounds to shield the brain
Prevention Recruiting nowThis study is testing whether a weight loss program can help prevent or delay Alzheimer's disease in adults with Down syndrome. 81 adults with Down syndrome who are overweight but do not have dementia will be assigned to either a weight loss group or a general health education gr…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Prevention
Last updated Mar 24, 2026 12:02 UTC
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Scientists test if Alzheimer's patients can be taught to stop falling
Prevention Recruiting nowThis study aims to see if people with mild Alzheimer's disease can learn and remember skills to prevent dangerous falls. Researchers will give one group special balance training using controlled pushes on a treadmill, while another group gets no training. They will then track how…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Georgia State University • Aim: Prevention
Last updated Mar 20, 2026 14:48 UTC
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Phone app aims to lighten load for Alzheimer's caregivers
Symptom relief Recruiting nowThis study is testing whether a mobile app called Brain CareNotes can help reduce stress for people caring for loved ones with Alzheimer's disease. Researchers will compare the app against a basic education app over 12 months with 184 caregiver participants. The goal is to see if…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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New program aims to ease the strain on dementia caregivers
Symptom relief Recruiting nowThis study is testing a new support program for people with Alzheimer's or dementia and their caregivers during the transition from a nursing facility to home or another care setting. The program provides extra help and education to nursing facility staff and assigns a specialist…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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New pill aims to calm agitation in Alzheimer's patients
Symptom relief Recruiting nowThis study is testing whether a new oral medication called BMS-986368 can safely reduce agitation in people with Alzheimer's disease. About 120 participants will be randomly assigned to receive either the drug or a placebo to compare the effects. The main goal is to see if the dr…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: Celgene • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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Could a cannabis pill calm Alzheimer's agitation?
Symptom relief Recruiting nowThis study is testing whether a new oral medication called IGC-AD1, which contains THC (the main active compound in cannabis) and melatonin, can safely reduce agitation in people with Alzheimer's disease. It will involve about 164 participants aged 60 and older who have significa…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: IGC Pharma, LLC • Aim: Symptom relief
Last updated Mar 30, 2026 14:35 UTC
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New hope for calming Alzheimer's agitation
Symptom relief Recruiting nowThis study is testing whether a combination of two medications called KarXT and KarX-EC can safely reduce agitation in people with Alzheimer's disease. The trial will involve 352 adults with Alzheimer's who experience significant agitation, comparing the active treatment to a pla…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE3 • Sponsor: Bristol-Myers Squibb • Aim: Symptom relief
Last updated Mar 30, 2026 14:33 UTC
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Could a cannabis drug calm Alzheimer's agitation?
Symptom relief Recruiting nowThis study is testing whether nabilone, a synthetic drug similar to cannabis, can safely and effectively treat agitation in people with Alzheimer's disease. Agitation is a common and distressing symptom that speeds up the need for nursing home care and increases caregiver stress.…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE3 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Symptom relief
Last updated Mar 30, 2026 14:33 UTC
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Zapping Alzheimer's agitation: new brain stimulation combo tested
Symptom relief Recruiting nowThis small pilot study is testing whether combining two painless, non-invasive brain stimulation techniques can help manage difficult behavioral and emotional symptoms in people with Alzheimer's disease. The study aims to see if the treatment process is practical for patients and…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Baylor College of Medicine • Aim: Symptom relief
Last updated Mar 30, 2026 14:33 UTC
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New phone training aims to ease silent pain for dementia patients
Symptom relief Recruiting nowThis study is testing a phone-based training program called PICT for family caregivers of people with Alzheimer's or related dementias. The program teaches caregivers how to spot signs of pain in their loved ones and how to talk about it effectively with healthcare providers. Res…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Weill Medical College of Cornell University • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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Could cannabis compound calm Alzheimer's agitation?
Symptom relief Recruiting nowThis study is testing whether CBD (cannabidiol) capsules can help reduce agitation in people with Alzheimer's disease. Forty participants will try both CBD and a placebo pill in a random order over 19 weeks to see which works better. Researchers will measure changes in agitation,…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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Zapping the brain to fight forgetfulness: new hope for dementia patients?
Symptom relief Recruiting nowThis study is testing whether a gentle, non-invasive brain stimulation technique can improve symptoms like memory loss and confusion in people with Alzheimer's disease, Lewy body dementia, and other related conditions. Researchers will compare the effects of real stimulation to a…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Kuopio University Hospital • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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Could a simple hearing aid calm dementia agitation? johns hopkins investigates
Symptom relief Recruiting nowThis study is testing whether providing hearing aids and communication support to older adults with both Alzheimer's disease and hearing loss can reduce distressing symptoms like agitation and improve their relationship with their caregiver. Researchers will enroll 300 participan…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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Text messages aim to lift spirits of stressed Alzheimer's caregivers
Symptom relief Recruiting nowThis study is testing a text message support program called CuidaTEXT for Latino caregivers of family members with Alzheimer's or related dementias. Researchers want to see if receiving daily tips, education, and encouragement via text can help reduce caregivers' feelings of depr…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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Magnetic pulses target depression in Alzheimer's patients
Symptom relief Recruiting nowThis study is testing a non-invasive brain stimulation treatment for depression in people over 60 who have Alzheimer's disease or mild memory loss. Participants who haven't been helped by antidepressant medications will receive daily magnetic stimulation sessions for four weeks. …
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Rotman Research Institute at Baycrest • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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New hope for calming Alzheimer's agitation: Long-Term drug safety tested
Symptom relief Recruiting nowThis study aims to understand the long-term safety and side effects of two drug combinations, KarXT and KarX-EC, for treating agitation in people with Alzheimer's disease. It is open to 600 participants who have already completed one of two previous related studies. The main goal…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE3 • Sponsor: Bristol-Myers Squibb • Aim: Symptom relief
Last updated Mar 30, 2026 14:27 UTC
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New hope for calming Alzheimer's hallucinations and delusions
Symptom relief Recruiting nowThis study is testing whether a medication called KarXT can safely reduce distressing psychosis symptoms like hallucinations and delusions in people with Alzheimer's disease. It will involve about 406 adults aged 55-90 who have been diagnosed with Alzheimer's and have experienced…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE3 • Sponsor: Karuna Therapeutics • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Can outdoor fun like gardening help ease memory loss?
Symptom relief Recruiting nowThis study is testing whether a program of enjoyable outdoor activities, like gardening or walking a dog, is practical and liked by people with memory challenges and their care partners. Researchers want to see if this 'Green Activity Program' helps people stay active and improve…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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New drug trial aims to calm agitation in Alzheimer's patients
Symptom relief Recruiting nowThis study is testing whether a combination of two medications, KarXT and KarX-EC, can safely reduce agitation in people with Alzheimer's disease. The trial will involve 352 adults who experience significant agitation related to their Alzheimer's. Participants will receive either…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE3 • Sponsor: Bristol-Myers Squibb • Aim: Symptom relief
Last updated Mar 27, 2026 12:39 UTC
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New 3D calendar aims to anchor Alzheimer's patients in time
Symptom relief Recruiting nowThis study is testing a new 3D calendar tool designed to help people with mild to moderate Alzheimer's or dementia who get confused about the time, date, or season. Researchers will observe 20 hospitalized patients to see if using the tool daily helps them stay oriented. The main…
Matched conditions: ALZHEIMER DISEASE
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Mar 27, 2026 12:39 UTC
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Brain zap and pill combo tested to rekindle motivation in dementia
Symptom relief Recruiting nowThis study is testing whether a two-part treatment can help reduce apathy, a common loss of motivation, in people with Alzheimer's disease. Researchers are combining a stimulant medication (methylphenidate) with a gentle, non-invasive brain stimulation technique. The goal is to s…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Symptom relief
Last updated Mar 27, 2026 12:39 UTC
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Magic mushroom drug tested to lift depression in Alzheimer's patients
Symptom relief Recruiting nowThis small, early-stage study from Johns Hopkins University is testing whether the psychedelic compound psilocybin, given in a controlled setting with support, can safely reduce depression in people with mild cognitive impairment or early Alzheimer's disease. Up to 20 participant…
Matched conditions: ALZHEIMER DISEASE
Phase: EARLY_PHASE1 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Mar 24, 2026 12:02 UTC
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Zapping the blues away? home brain stimulation tested for Alzheimer's mood problems
Symptom relief Recruiting nowThis study is testing whether a home-based brain stimulation device can help improve mood, anxiety, and apathy in people with Alzheimer's disease. Researchers are enrolling 24 older adults with Alzheimer's and their caregivers to use the device at home for 30-minute sessions. The…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Symptom relief
Last updated Mar 20, 2026 14:48 UTC
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New learning method aims to ease the burden on dementia caregivers
Symptom relief Recruiting nowThis study is testing a new way to teach family caregivers of people with dementia. It compares a special learning method that uses practice quizzes to a traditional reading approach. The goal is to see if the new method helps caregivers remember information better, feel more con…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Virginia Wesleyan University • Aim: Symptom relief
Last updated Mar 20, 2026 14:47 UTC
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New app aims to ease the heavy load for rural dementia caregivers
Symptom relief Recruiting nowThis study is testing a smartphone app called 'Brain CareNotes' to see if it helps people caring for family members with dementia in rural areas. The app is designed to reduce caregiver stress and help manage difficult dementia-related behaviors. Researchers will compare the app …
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Richard Holden • Aim: Symptom relief
Last updated Mar 17, 2026 13:09 UTC
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New hope for easing the hidden pain of dementia
Symptom relief Recruiting nowThis study is testing if a common pain medication (oxycodone/acetaminophen) is safe and effective for treating chronic pain in people who have Alzheimer's disease. It will involve 10 participants who will take the medication daily for 12 weeks. Researchers will track changes in p…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE3 • Sponsor: Xuanwu Hospital, Beijing • Aim: Symptom relief
Last updated Mar 11, 2026 14:53 UTC
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New digital therapy aims to calm anxiety for those facing early dementia
Symptom relief Recruiting nowThis study is testing if a special computer-based program can help reduce anxiety and stress in older adults with early-stage memory loss or mild Alzheimer's disease. It also looks at whether the program helps reduce the strain on their family caregivers. Researchers will compare…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Florida State University • Aim: Symptom relief
Last updated Mar 09, 2026 14:24 UTC
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New online program aims to lift the burden for dementia caregivers
Symptom relief Recruiting nowThis study is testing a 6-week online skills training program for family members caring for someone with Alzheimer's or another dementia. The program, called Learning Skills Together, teaches practical care tasks and coping strategies. Researchers want to see if it helps caregive…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Case Western Reserve University • Aim: Symptom relief
Last updated Mar 06, 2026 15:37 UTC
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New hope for memory? experimental drug added to standard Alzheimer's care
Symptom relief Recruiting nowThis study is testing whether a new drug called MK-1167, when added to standard Alzheimer's medication, can help improve memory, thinking, and daily function for people with mild to moderate Alzheimer's dementia. Researchers will compare the effects of MK-1167 against a placebo i…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Symptom relief
Last updated Mar 02, 2026 15:28 UTC
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MIT tests light & sound therapy for Alzheimer's prevention
Knowledge-focused Recruiting nowThis study is testing whether gentle light and sound stimulation at a specific frequency (40Hz) can change brain activity in healthy adults and people with Alzheimer's disease. Researchers want to see if this non-invasive approach is safe and affects brain connections, thinking s…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: Massachusetts Institute of Technology • Aim: Knowledge-focused
Last updated Apr 01, 2026 21:26 UTC
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Could a simple blood test track Alzheimer's treatment?
Knowledge-focused Recruiting nowThis study aims to see if specific blood tests can accurately track how well the Alzheimer's drug lecanemab is working. Researchers will observe 400 patients in China with early Alzheimer's who are already taking lecanemab. They will collect blood samples and brain scans over 18 …
Matched conditions: ALZHEIMER DISEASE
Sponsor: First Affiliated Hospital of Zhejiang University • Aim: Knowledge-focused
Last updated Apr 01, 2026 21:26 UTC
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New scan seeks clues to Alzheimer's in the brain
Knowledge-focused Recruiting nowThis study is testing a new type of brain scan to measure a protein called fibrin in people with and without Alzheimer's disease. Researchers want to see if there are differences in fibrin levels between healthy individuals and those with memory problems. The goal is to better un…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Apr 01, 2026 21:26 UTC
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Can speaking two languages help protect the brain? new study investigates
Knowledge-focused Recruiting nowThis study aims to understand if speech therapy tailored for bilingual people can help those with primary progressive aphasia, a condition that causes worsening language problems. Researchers will test 60 bilingual participants to see if practicing in both their languages improve…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: University of Texas at Austin • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Scientists map toxic protein in living Alzheimer's brains
Knowledge-focused Recruiting nowThis study uses special brain scans to measure and map a harmful protein called tau in people with Alzheimer's disease. Researchers will scan 160 participants already enrolled in an ongoing Alzheimer's research program to see how tau buildup relates to race, heart health risks, a…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE1 • Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Massive scottish study launches to unlock Dementia's secrets
Knowledge-focused Recruiting nowThis study aims to understand how dementia develops by tracking the memory, thinking, health, and lifestyle of 10,000 people in Scotland over many years. It will gather detailed information to identify risk factors and different patterns of disease progression. The goal is to bui…
Matched conditions: ALZHEIMER DISEASE
Sponsor: Brain Health Scotland Life Sciences Ltd • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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New tool aims to help doctors talk about tough future choices with dementia patients
Knowledge-focused Recruiting nowThis study is testing a new toolkit designed to help primary care doctors and nurses have better conversations with people living with dementia about their future care wishes. It will compare the toolkit to usual care across 20 clinics to see if it leads to more and higher-qualit…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Hunting for the Brain's shield: blood test could predict Alzheimer's speed
Knowledge-focused Recruiting nowThis study aims to find new blood markers that can predict how quickly Alzheimer's disease will progress in a person. Researchers will follow 244 patients with early Alzheimer's for three years, taking blood samples to measure 'resilience'—the brain's ability to resist damage. Th…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists hunt for Alzheimer's early warning signs in blood and brain
Knowledge-focused Recruiting nowThis study aims to understand how early brain cell connections break down in Alzheimer's disease. Researchers will compare 20 people with Alzheimer's to 20 healthy volunteers, measuring specific substances in their blood and spinal fluid. The goal is to find biological markers th…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Massive 5000-Person brain health study launches in hong kong
Knowledge-focused Recruiting nowThis study aims to follow 5000 adults over many years to understand what factors lead to brain diseases like stroke and dementia. It will track people who already have a diagnosis, are at high risk, or are currently healthy, using questionnaires and medical records. The goal is t…
Matched conditions: ALZHEIMER DISEASE
Sponsor: Chinese University of Hong Kong • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists launch major study to map the journey of early Alzheimer's
Knowledge-focused Recruiting nowThis study aims to understand how early-onset Alzheimer's disease changes over time in people aged 40-64. Researchers will follow about 850 participants with and without memory problems for 2-4 years, using brain scans, memory tests, and fluid samples. The goal is to gather detai…
Matched conditions: ALZHEIMER DISEASE
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:10 UTC
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Magnets for memory: can brain zaps help Alzheimer's patients?
Knowledge-focused Recruiting nowThis research study aims to understand how non-invasive magnetic brain stimulation affects memory and brain function. It involves older adults with mild memory problems and those without cognitive issues. Participants receive repeated brain stimulation sessions while researchers …
Matched conditions: ALZHEIMER DISEASE
Phase: EARLY_PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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Scientists hunt for Alzheimer's earliest warning signs in the brain
Knowledge-focused Recruiting nowThis study aims to understand how a small, deep-brain area called the locus coeruleus is involved in the earliest stages of Alzheimer's disease. Researchers will use brain scans, eye-tracking, and simple nerve stimulation in 150 adults to see if changes in this area can predict f…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Cornell University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Could a simple eye scan spot dementia early?
Knowledge-focused Recruiting nowThis study aims to see if a special, non-invasive eye scan can detect changes in the retina linked to dementia. Researchers will compare scans from 20 people with mild dementia to scans from people without dementia. The goal is to find new ways to identify the disease by looking …
Matched conditions: ALZHEIMER DISEASE
Sponsor: Oregon Health and Science University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Massive 40,000-Person hunt for Alzheimer's clues in families
Knowledge-focused Recruiting nowThis study aims to build a detailed picture of inherited Alzheimer's disease in China by tracking 40,000 people from affected families over time. Researchers will collect genetic, memory test, brain scan, and blood sample data to understand how the disease starts and progresses. …
Matched conditions: ALZHEIMER DISEASE
Sponsor: Capital Medical University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:31 UTC
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Scientists map the Body's inner rhythms in autism, Alzheimer's, and more
Knowledge-focused Recruiting nowThis study aims to understand how the brain and body work together by measuring signals like brain waves, heart rate, and movement. Researchers will compare these signals in 100 people, including healthy individuals and those with conditions like autism spectrum disorder, ADHD, o…
Matched conditions: ALZHEIMER DISEASE
Sponsor: Rutgers University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC
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Do COVID vaccines affect your brain? major study seeks answers
Knowledge-focused Recruiting nowThis study aims to understand if COVID-19 vaccines affect brain health, specifically looking for signs of stroke or dementia. Researchers in Hong Kong will follow 500 healthy adults, comparing brain scans and memory tests from before and after vaccination to those from unvaccinat…
Matched conditions: ALZHEIMER DISEASE
Sponsor: Chinese University of Hong Kong • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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New brain scan aims to pinpoint hidden cause of dementia
Knowledge-focused Recruiting nowThis study is testing a new type of brain scan to see if it can detect a specific protein called tau, which builds up in some forms of dementia. Researchers will compare scans from people with different types of Alzheimer's disease and frontotemporal dementia to scans from health…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE3 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Massive 7-Year hunt for Alzheimer's early warning signs begins
Knowledge-focused Recruiting nowThis study aims to understand how Alzheimer's disease develops by tracking people at risk for the condition over seven years. It will follow 3,400 participants with normal memory to see if a specific blood test can predict future declines in thinking skills. The study does not te…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:41 UTC
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Simple blood test may predict which elderly patients face highest risk after hospital stay
Knowledge-focused Recruiting nowThis study aims to see if certain proteins in the blood, related to Alzheimer's disease and brain injury, can help predict which older hospitalized patients are most likely to die or be readmitted to the hospital. Researchers will follow 400 older patients for one year after thei…
Matched conditions: ALZHEIMER DISEASE
Sponsor: Istituto Nazionale di Ricovero e Cura per Anziani • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Can better sleep calm the storm of Alzheimer's?
Knowledge-focused Recruiting nowThis study is testing whether improving sleep can help reduce anxiety, depression, and agitation in people with early Alzheimer's disease or memory loss. Researchers will give 150 participants either a proven sleep therapy program or a comparison activity to see if better sleep l…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Could an eye scan spot Alzheimer's before symptoms appear?
Knowledge-focused Recruiting nowThis study is testing if new, non-invasive eye imaging techniques can find unique signs in the retina linked to Alzheimer's disease and other memory disorders. Researchers will compare detailed scans of the eye's blood vessels and structure in 450 people with memory complaints ag…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Scientists hunt for hidden clues in 1200 patients to unlock brain disease mysteries
Knowledge-focused Recruiting nowThis study aims to better understand diseases like Alzheimer's and Parkinson's by analyzing the genes, proteins, and other molecules in people who have them. Researchers will collect blood and other samples from 1200 participants to look for patterns that could lead to new ways t…
Matched conditions: ALZHEIMER DISEASE
Sponsor: Ospedale Policlinico San Martino • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Simple blood test could spot Alzheimer's years before symptoms
Knowledge-focused Recruiting nowThis study aims to see if measuring certain proteins in a person's blood can accurately predict who will develop Alzheimer's disease or experience cognitive decline. Researchers will follow 1,800 adults aged 60 and older, some with memory concerns and some without, for several ye…
Matched conditions: ALZHEIMER DISEASE
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:37 UTC
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Vanderbilt launches major study to unlock Alzheimer's secrets
Knowledge-focused Recruiting nowThis study aims to build a detailed research database to help scientists develop better ways to detect, prevent, and treat Alzheimer's disease. It will enroll 1,000 adults aged 60 and older, including those with and without memory problems. Participants will be followed annually …
Matched conditions: ALZHEIMER DISEASE
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Scientists test new pill formula for epilepsy and Alzheimer's
Knowledge-focused Recruiting nowThis early-stage study aims to see how a new version of an experimental capsule (NPT 2042) is absorbed by the body compared to the original version. It involves a small group of healthy adults who will take single doses of each capsule. The goal is to gather basic information to …
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE1 • Sponsor: NeuroPro Therapeutics, Inc. • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:03 UTC
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Scientists scan brains to unlock secrets of memory disorders
Knowledge-focused Recruiting nowThis study aims to better understand how Alzheimer's disease and Lewy body disease affect the brain over time. Researchers will observe 90 participants—including people with these conditions and healthy individuals—using brain scans, memory tests, and measurements of brain wave a…
Matched conditions: ALZHEIMER DISEASE
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:02 UTC
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Scientists probe hormone link to Women's Alzheimer's risk
Knowledge-focused Recruiting nowThis study aims to understand if a woman's natural hormones are connected to how she ages and her risk of developing Alzheimer's disease. It will involve about 614 women aged 60 and older, who will undergo brain scans, memory tests, and physical assessments. The goal is to gather…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE4 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC
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Common vitamin tested as potential Alzheimer's fighter
Knowledge-focused Recruiting nowThis study is testing if a common B-vitamin called niacin can get into the brain and spinal fluid of people with Alzheimer's disease. Researchers will give 30 participants either a 500mg niacin pill or a placebo (sugar pill) for 60 days. The main goal is to measure how much niaci…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:18 UTC
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Scientists use Super-Powered scans to unlock Brain's secrets in aging and disease
Knowledge-focused Recruiting nowThis study aims to understand how the brain changes and adapts in various neurological conditions and during normal aging. Researchers will use advanced, high-powered MRI scans to look at brain structure, function, and energy use in 700 participants, including people with disease…
Matched conditions: ALZHEIMER DISEASE
Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:15 UTC
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Invisible sensor tracks Alzheimer's patients at home
Knowledge-focused Recruiting nowThis study aims to see if a small, contactless device placed in the bedroom can detect subtle changes in sleep patterns, walking speed, and daily activity in people with mild memory problems or early Alzheimer's disease. About 40 participants will have the device monitor them at …
Matched conditions: ALZHEIMER DISEASE
Sponsor: Mclean Hospital • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC
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Massive national hunt for Alzheimer's genes launches
Knowledge-focused Recruiting nowThis study aims to find genes linked to Alzheimer's disease by collecting genetic samples from families with multiple affected members. It is enrolling up to 10,000 participants from families with at least two living relatives diagnosed with Alzheimer's or dementia. The collected…
Matched conditions: ALZHEIMER DISEASE
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Mar 20, 2026 14:47 UTC
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Could stress unlock the secret to predicting Alzheimer's decline?
Knowledge-focused Recruiting nowThis study aims to understand how the body's response to stress and a person's genes might predict future memory and thinking problems in people with mild cognitive impairment, a potential early sign of Alzheimer's disease. Researchers will enroll 240 participants to undergo brie…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC
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Scientists hunt for early warning signs of dementia
Knowledge-focused Recruiting nowThis study aims to create a better prediction model for how memory and thinking problems worsen over time in people with early dementia or mild cognitive impairment. Researchers will collect blood samples, perform brain scans, conduct memory tests, and gather information from clo…
Matched conditions: ALZHEIMER DISEASE
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:41 UTC
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Scientists hunt for early warning signs of memory loss in the brain
Knowledge-focused Recruiting nowThis study aims to understand the early brain changes that happen before noticeable memory problems begin. Researchers will use MRI and PET brain scans, along with memory tests, to track 300 older adults with normal thinking skills over time. The goal is to find the best combinat…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE3 • Sponsor: University of California, Irvine • Aim: Knowledge-focused
Last updated Mar 17, 2026 13:08 UTC
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Scientists scan brains to unlock Alzheimer's secrets
Knowledge-focused Recruiting nowThis study uses special brain scans (PET and MRI) to measure amyloid plaques in people with and without Alzheimer's disease. Researchers want to understand how these plaques, along with a person's race and heart health factors, relate to memory and thinking problems. The study is…
Matched conditions: ALZHEIMER DISEASE
Phase: PHASE2 • Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Mar 13, 2026 15:06 UTC
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Georgia launches major Alzheimer's drug tracking program
Knowledge-focused Recruiting nowThis study creates a registry to track how new FDA-approved Alzheimer's drugs work in real-world settings across Georgia. Researchers will follow 735 Medicare patients with early Alzheimer's who receive these anti-amyloid medications during regular clinic visits. The goal is to u…
Matched conditions: ALZHEIMER DISEASE
Sponsor: Emory University • Aim: Knowledge-focused
Last updated Mar 13, 2026 15:06 UTC
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Scientists scan brain fluid to unlock secrets of memory loss
Knowledge-focused Recruiting nowThis Mayo Clinic study uses MRI scans to measure how fluid moves around the brain. Researchers want to see if fluid flow differs between healthy adults and people with conditions like Alzheimer's disease or hydrocephalus. The goal is to improve diagnosis and understanding of thes…
Matched conditions: ALZHEIMER DISEASE
Phase: NA • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Mar 11, 2026 14:53 UTC