PET scans reveal how inflammation drives Alzheimer's variants
NCT ID NCT04576793
First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time
Summary
This study uses special PET scans to measure brain inflammation and tau protein buildup in people with different forms of Alzheimer's disease, including those with memory, vision, or language problems. Researchers aim to understand how inflammation relates to other brain changes and symptoms over time. Participants include older adults with mild cognitive impairment, Alzheimer's variants, and healthy volunteers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- 11C-ER176 and 18F-MK6240 (radioactive tracers for PET scans)
- What this could lead to
- If successful, this could clarify how brain inflammation relates to Alzheimer's progression and symptoms, potentially guiding future treatments.
- What could go wrong
- This is an observational imaging study, not a treatment trial. The tracers are experimental and may not reliably measure inflammation or tau across all participants.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Columbia University Irving Medical Center
RECRUITINGNew York, New York, 10032, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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