Sleep pill may slow Alzheimer's by clearing brain proteins

NCT ID NCT06274528

First seen Nov 05, 2025 · Last updated May 12, 2026 · Updated 21 times

Summary

This study tests whether the sleep aid lemborexant can lower levels of amyloid-beta and tau proteins in the blood—proteins linked to Alzheimer's disease. Researchers will enroll 201 healthy adults aged 65 and older. Participants will take either lemborexant or a placebo to see if the drug changes these protein levels and to check for side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ALZHEIMER DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Washington University in St. Louis, School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

Conditions

Explore the condition pages connected to this study.