Can flaxseed oil protect the aging brain? new trial targets APOE4 carriers

NCT ID NCT07392723

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a daily dose of flaxseed oil (alpha-linolenic acid) can slow memory loss and protect brain blood vessels in older adults with mild cognitive impairment and the APOE4 gene, which raises Alzheimer's risk. Twenty participants will take either the oil or a placebo for six months. Researchers will measure changes in thinking skills and brain scans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Alpha-linolenic acid (ALA), also known as flaxseed oil

What this could lead to

If it works, this could point toward a simple, safe dietary supplement to slow memory loss in people at high genetic risk for Alzheimer's.

What could go wrong

This is a very small, early pilot trial with only 20 people. The supplement may not improve cognition or brain health, and results may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ALZHEIMER DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Apolipoprotein E, Deficiency or Defect of cognitive disorder Cognitive Dysfunction hyperlipoproteinemia type 3 Nerve Degeneration Alzheimer disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Rutgers - Institute for Health

    RECRUITING

    New Brunswick, New Jersey, 08901, United States

    Contact Email: •••••@•••••