New Alzheimer's drug targets brain receptors to boost memory

NCT ID NCT06995573

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new drug called NSC001 in 90 people with mild to moderate Alzheimer's disease. The drug is designed to activate a specific receptor in the brain (M1 muscarinic) that may help with memory and thinking. The main goal is to check if the drug is safe and tolerable, while also exploring if it improves cognitive function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
NSC001
What this could lead to
If successful, this could point toward a new treatment to ease cognitive symptoms in Alzheimer's disease.
What could go wrong
This is an early phase 2a trial with only 90 participants, focused mainly on safety. It may not show clear cognitive benefits, and the drug could have side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinic Altenburger Land GmbH

    NOT_YET_RECRUITING

    Altenburg, 04600, Germany

  • Dynamikos GmbH Institut fuer Studien zur Psychischen Gesundheit

    RECRUITING

    Mannheim, 68165, Germany

  • Gemeinnuetzige Salzburger Landeskliniken Betriebsgesellschaft GmbH

    RECRUITING

    Salzburg, State of Salzburg, 5020, Austria

  • Medical University Innsbruck

    RECRUITING

    Innsbruck, 6020, Austria

  • Medical University Vienna

    RECRUITING

    Vienna, 1090, Austria

  • SANOS Clinic

    RECRUITING

    Ratingen, 40882, Germany

  • Universitaetsmedizin Goettingen

    RECRUITING

    Göttingen, 37075, Germany

  • University Clinic Köln

    RECRUITING

    Cologne, 50937, Germany

  • University Hospital Graz

    RECRUITING

    Graz, Styria, 8036, Austria

  • Zentrum fuer klinische Forschung Dr. I. Schoell GmbH

    RECRUITING

    Bad Homburg, 61348, Germany

    Contact Email: •••••@•••••

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