New pill aims to calm Alzheimer's psychosis in landmark trial
NCT ID NCT06540833
First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 4 times
Summary
This study tests an experimental drug, ITI-1284, to see if it can safely reduce psychosis symptoms like hallucinations and delusions in people with Alzheimer's disease. About 370 participants will receive either the drug or a placebo, and doctors will track changes in symptom severity over time. The goal is to improve quality of life for patients and their caregivers.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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ATP Clinical Research
COMPLETEDOrange, California, 92866, United States
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Advanced Research Center, Inc
RECRUITINGAnaheim, California, 92805, United States
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Allied Biomedical Research Institute (ABRI), Inc
RECRUITINGMiami, Florida, 33155-4630, United States
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Ambulatory for Individual Practice for Specialized Medical Care in Psychiatry Dr. Ivo Natsov ET
RECRUITINGCherven Bryag, 5980, Bulgaria
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Bio Behavioral Health
RECRUITINGToms River, New Jersey, 08755, United States
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Brain Matters Research
COMPLETEDDelray Beach, Florida, 33445, United States
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Centrul de Evaluarea si Tratament al Toxicodependentelor pentru Tineri Sf. Stelian
SUSPENDEDBucharest, 60222, Romania
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Clinical Center Dr Dragisa Misovic Dedinje
RECRUITINGBelgrade, 11000, Serbia
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Clinical Research of Brandon
SUSPENDEDBrandon, Florida, 33511, United States
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Combined Research Orlando
COMPLETEDOrlando, Florida, 32803, United States
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Crystal Comfort s.r.o.
RECRUITINGVranov nad Topľou, 09301, Slovakia
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DCC 'Sv. Vrach and Sv. Sv. Kuzma and Damyan', OOD
RECRUITINGSofia, 1408, Bulgaria
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Envision Trials LLC
RECRUITINGBonita Springs, Florida, 34134, United States
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Epamed sro
RECRUITINGKošice, 4001, Slovakia
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Fakultni nemocnice u sv. Anny v Brne
RECRUITINGBrno, 60200, Czechia
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Healthcare Innovations Institute Inc
COMPLETEDCoral Springs, Florida, 33067, United States
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Homestead Associates in Research Inc
RECRUITINGHomestead, Florida, 33033, United States
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Horizon Clinical Research Group
RECRUITINGCypress, Texas, 77065, United States
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Hosp. Gral. de Albacete
RECRUITINGAlbacete, 02006, Spain
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Hosp. Prov. de Zamora
RECRUITINGZamora, 49021, Spain
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Hosp. Viamed Montecanal
SUSPENDEDZaragoza, 50012, Spain
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INEP medical s.r.o.
COMPLETEDPrague, 18600, Czechia
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Intercoastal Medical Group
RECRUITINGSarasota, Florida, 34239, United States
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K2 Medical Research
RECRUITINGMaitland, Florida, 32751, United States
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Medical Center Hera EOOD
RECRUITINGSofia, 1510, Bulgaria
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Medical Center Intermedica, OOD
RECRUITINGSofia, 1680, Bulgaria
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Medical Center Sv Dimitar Blagoevgrad
RECRUITINGBlagoevgrad, 2700, Bulgaria
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Mental Health Center - Vratsa EOOD
COMPLETEDVratsa, 3000, Bulgaria
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Mental Health Centre Prof. N Shipkovenski EOOD
RECRUITINGSofia, 1377, Bulgaria
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NEURES s r o
RECRUITINGKrompachy, 05342, Slovakia
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NEUROHK s r o
RECRUITINGHradec Králové, 50002, Czechia
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Neuro Care
COMPLETEDKatowice, 40-749, Poland
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Neuro Health Centrum s r o
RECRUITINGBrno, 62800, Czechia
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Neurologicka ambulancia MUDr.Dupejova s.r.o.
COMPLETEDBanská Bystrica, 97404, Slovakia
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New Hope Clinical Research
RECRUITINGCharlotte, North Carolina, 28211, United States
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Northwest Clinical Research Center
RECRUITINGBellevue, Washington, 98007, United States
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Ocean Blue Medical Research Center Inc.
SUSPENDEDMiami, Florida, 33144, United States
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Osrodek Badawczo Naukowo Dydaktyczny Chorob Otepiennych UM im Piastow Slaskich we Wroclawiu
RECRUITINGŚcinawa, 59-330, Poland
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Pharmacology Research Institute
TERMINATEDLos Alamitos, California, 90720, United States
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Polyclinic Neuron
RECRUITINGZagreb, 10000, Croatia
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Przychodnia Srodmiescie SP. z o.o.
COMPLETEDBydgoszcz, 85 080, Poland
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Psych Me Medical Research Inc
SUSPENDEDTampa, Florida, 33614, United States
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Psychiatric Clinic "VRAPCE"
RECRUITINGZagreb, 10090, Croatia
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SC Carpe Diem SRL
RECRUITINGSibiu, 550281, Romania
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Science Connections LLC
RECRUITINGDoral, Florida, 33178, United States
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South Florida Research Phase I-IV
RECRUITINGMiami, Florida, 33166, United States
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Special Hospital for Psychiatric Diseases Kovin
COMPLETEDKovin, 26220, Serbia
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Special Hospital for Psychiatric Diseases Sveti Vracevi
RECRUITINGNovi Kneževac, 23330, Serbia
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Spitalul Clinic de Psihiatrie Prof Dr Alexandru Obregia
RECRUITINGBucharest, 041914, Romania
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Spitalul Clinic de Psihiatrie Prof Dr Alexandru Obregia 1
RECRUITINGBucharest, 040874, Romania
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Spitalul De Psihiatrie Elisabeta Doamna Galaţi
RECRUITINGGalati, 800179, Romania
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Spitalul Universitar de Urgenta Militar Central 'Dr. Carol Davila'
RECRUITINGBucharest, 010825, Romania
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Sunshine Medical Solution
RECRUITINGMiami, Florida, 33186, United States
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Sunwise Clinical Research
RECRUITINGWalnut Creek, California, 94596, United States
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UMHAT Prof. Dr. St. Kirkovich AD
RECRUITINGStara Zagora, 6003, Bulgaria
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University Clinical Center Kragujevac
RECRUITINGKragujevac, 34000, Serbia
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University Clinical Center NIS
RECRUITINGNiš, 18000, Serbia
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University Hospital Centre Zagreb
SUSPENDEDZagreb, 10000, Croatia
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University Hospital Centre Zagreb 1
COMPLETEDZagreb, 10000, Croatia
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University of South Florida
RECRUITINGTampa, Florida, 33613, United States
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University of Texas Health Science Center at San Antonio
RECRUITINGSan Antonio, Texas, 78229-3900, United States
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Univerzitna nemocnica Bratislava
RECRUITINGBratislava, 81369, Slovakia
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Univerzitna nemocnica L. Pasteura Kosice
RECRUITINGKošice, 04190, Slovakia
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Wellness Research Center
RECRUITINGMiami, Florida, 33135, United States
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Wr Pri Llc
COMPLETEDNewport Beach, California, 92660, United States
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Other studies related to the condition(s) this trial covers.
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