Could a drug cocktail boost brain function in early dementia?
NCT ID NCT06467539
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 2 trial tests whether adding an antioxidant to an NMDA-enhancing drug (DAOIB) improves thinking and memory more than the drug alone in people with early Alzheimer's or mild cognitive impairment. Eighty participants will take the combination or a placebo for 24 weeks. Researchers will measure changes in cognitive tests and daily function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
DAOIB (an NMDA-enhancing agent) plus an antioxidant
What this could lead to
If successful, this could point toward a new combination treatment that slows cognitive decline in early Alzheimer's or mild cognitive impairment.
What could go wrong
This is a small Phase 2 trial with only 80 participants, so results may not be conclusive. The combination may not work better than DAOIB alone, and side effects are possible.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Chang Gung Memorial Hospital
RECRUITINGKaohsiung City, 886, Taiwan
Contact Phone: •••-•••-•••• Email: •••••@•••••
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