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New scan could spot Alzheimer's hallmark before death

NCT ID NCT05641688

Recruiting now Diagnosis Sponsor: Lantheus Biosciences Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a special PET scan using [18F]PI-2620 to see if it can accurately detect tau tangles in the brains of people with Alzheimer's disease. About 200 adults aged 50 and older with a short life expectancy will get the scan. After they pass away, researchers will compare the scan results to actual brain tissue samples to see how well the scan works.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER DISEASE

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Alzheimer's Disease Center

    RECRUITING

    Braintree, Massachusetts, 02184, United States

  • American Carolina Clinical Research LLC

    TERMINATED

    Charlotte, North Carolina, 28273, United States

  • Banner Sun Health Research Institute

    RECRUITING

    Sun City, Arizona, 85352, United States

  • Barrow Neurological Institute

    RECRUITING

    Phoenix, Arizona, 85013, United States

  • Baylor Research Institute

    RECRUITING

    Dallas, Texas, 75231, United States

  • Be Well Clinical Studies

    WITHDRAWN

    Lincoln, Nebraska, 68616, United States

  • Be Well Clinical Studies

    RECRUITING

    Round Rock, Texas, 78681, United States

  • Charter Research

    RECRUITING

    Winter Park, Florida, 32792, United States

  • ClinCloud Research

    RECRUITING

    Melbourne, Florida, 32940, United States

  • Darthmouth-Hitchcock Medical Center

    RECRUITING

    Lebanon, New Hampshire, 07366, United States

  • Esperanza Clinical

    RECRUITING

    Murrieta, California, 92562, United States

  • Galiz Research

    RECRUITING

    Hialeah, Florida, 33016, United States

  • Headlands Research

    WITHDRAWN

    Plymouth, Massachusetts, 02360, United States

  • Ichor Research

    RECRUITING

    Syracuse, New York, 13219, United States

  • Insight Clinical Trials LLC

    RECRUITING

    Beachwood, Ohio, 44131, United States

  • K2 Medical Research

    RECRUITING

    Lady Lake, Florida, 32159, United States

  • K2 Medical Research

    RECRUITING

    Maitland, Florida, 32751, United States

  • Miami Jewish Health Systems

    RECRUITING

    Miami, Florida, 33137, United States

  • Sante Clinical Research

    RECRUITING

    Kerrville, Texas, 78028, United States

  • Sutter Health

    RECRUITING

    San Francisco, California, 94114, United States

  • The Roskamp Institute

    TERMINATED

    Sarasota, Florida, 34243, United States

  • UC Los Angeles

    RECRUITING

    Los Angeles, California, 90095 - 7370, United States

  • UF College of Medicine - Jacksonville

    WITHDRAWN

    Jacksonville, Florida, 32209, United States

  • Valley Medical Research

    RECRUITING

    Centerville, Ohio, 45459, United States

  • Velocity Clinical Research

    RECRUITING

    East Syracuse, New York, 13057, United States

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