New hope for Alzheimer's pain: opioid combo trial launches

NCT ID NCT07323914

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial at Xuanwu Hospital in Beijing is testing whether a combination painkiller (oxycodone/acetaminophen) can safely ease chronic pain in 10 people with Alzheimer's disease. Participants will take the medication once daily for 12 weeks, with pain levels and side effects checked at several points. The goal is to find a better way to manage pain in patients who often cannot communicate their discomfort clearly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

oxycodone/acetaminophen (Tylex)

What this could lead to

If successful, this could provide a safe and effective way to manage chronic pain in people with Alzheimer's disease, improving their comfort and quality of life.

What could go wrong

This is a very small trial with only 10 participants, so results may not apply to everyone. Opioids carry risks like drowsiness, falls, and dependence, especially in older adults with dementia.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Chronic Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Xuanwu Hospital, Capital Medical University

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••