Could CBD calm Alzheimer's agitation? new trial aims to find out

NCT ID NCT06014424

Recruiting now Symptom relief Sponsor: Sunnybrook Health Sciences Centre Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 31, 2026 · Updated 3 times

Summary

This phase 2 trial is testing whether CBD capsules can safely reduce agitation in people with Alzheimer's disease. About 40 participants will receive both CBD and a placebo at different times to compare effects. The study also looks for biological markers that might predict who responds best.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cannabidiol (CBD) capsules
What this could lead to: If it works, this could point toward a new way to manage agitation in Alzheimer's disease without strong side effects.
What could go wrong: This is a small, early-phase trial with only 40 people. It may not show clear benefit, and CBD can cause drowsiness or stomach upset.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER DISEASE

Contacts and locations

Locations

Centre for Addiction and Mental Health
RECRUITING

Toronto, Ontario, Canada
London Health Sciences Centre
RECRUITING

London, Ontario, Canada
Ontario Shores Centre for Mental Health Sciences
RECRUITING

Whitby, Ontario, L1N 5S9, Canada
Sunnybrook Health Sciences Centre
RECRUITING

Toronto, Ontario, M3H0A7, Canada
University of Calgary
RECRUITING

Calgary, Alberta, T2N 4N1, Canada

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