Could magnetic pulses boost memory in Alzheimer's? new pilot study aims to find out
NCT ID NCT06597942
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study is testing whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can safely improve memory in people with mild-to-moderate Alzheimer's disease. The treatment targets the precuneus, a brain region important for memory. Fifty-four participants will receive either active or sham (placebo) stimulation over several sessions, along with memory tests, brain scans, and bloodwork to look for positive changes. The study's main goals are to see if the treatment is feasible and tolerable, and to gather early signs of whether it might help memory.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
repetitive transcranial magnetic stimulation (rTMS) targeting the precuneus
What this could lead to
If it works, this could point toward a non-invasive brain stimulation treatment to help maintain or improve memory in people with Alzheimer's disease.
What could go wrong
This is a small, early-phase pilot study (Phase 1/2) with only 54 participants. Previous rTMS research in Alzheimer's has shown mixed results, and the main goal here is to test feasibility and safety, not to prove effectiveness. Common side effects include headache and scalp discomfort; rare but serious risks include seizure.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UCLA TMS Clinical and Research Service
RECRUITINGLos Angeles, California, 90095, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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