Can a magnetic helmet sharpen memory in early Alzheimer's?

NCT ID NCT06538311

Recruiting now Knowledge-focused Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a non-invasive technique called repetitive Transcranial Magnetic Stimulation (rTMS) can improve memory and brain function in older adults with mild cognitive impairment or early Alzheimer's. Over 30 participants will receive both real and sham (placebo) stimulation in separate blocks, with memory tests and brain scans used to measure changes. The goal is to understand how rTMS affects brain networks, not to provide a treatment yet.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: repetitive Transcranial Magnetic Stimulation (rTMS)
What this could lead to: If successful, this could point toward a non-drug way to boost memory and brain connectivity in early Alzheimer's or mild cognitive impairment.
What could go wrong: This is a very early, small study (30 people) testing short-term effects only. It may not lead to lasting benefits or work for everyone.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction logopenic progressive aphasia primary progressive aphasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER DISEASE AMNESTIC SYMPTOMS LOGOPENIC PROGRESSIVE APHASIA MILD COGNITIVE IMPAIRMENT

Contacts and locations

Locations

Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02129, United States

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