Hope for Alzheimer's psychosis: new drug enters final testing phase

NCT ID NCT06947941

First seen Apr 22, 2026 · Last updated May 16, 2026 · Updated 4 times

Summary

This study tests whether a new combination drug, KarXT + KarX-EC, can safely reduce hallucinations and delusions in people with Alzheimer's disease. About 325 adults aged 55 to 90 with Alzheimer's and psychosis will receive either the drug or a placebo. The goal is to see if the drug eases these distressing symptoms without aiming to cure Alzheimer's itself.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Inland Psychiatric Medical Group.

    RECRUITING

    Chino, California, 91710, United States

    Contact Phone: •••-•••-••••

  • Local Institution - 0001

    WITHDRAWN

    Naples, Florida, 34105, United States

  • Local Institution - 0004

    NOT_YET_RECRUITING

    Motherwell, ML1 4UF, United Kingdom

    Contact

  • Local Institution - 0005

    NOT_YET_RECRUITING

    Exeter, Devon, EX12LU, United Kingdom

    Contact

  • Local Institution - 0009

    NOT_YET_RECRUITING

    Chertsey, Surrey, KT160PZ, United Kingdom

    Contact

  • Local Institution - 0015

    NOT_YET_RECRUITING

    Oxford, Oxfordshire, OX3 7JX, United Kingdom

    Contact

  • Local Institution - 0017

    NOT_YET_RECRUITING

    Sheffield, Yorkshire and the Humber, S47QQ, United Kingdom

    Contact

  • Local Institution - 0018

    NOT_YET_RECRUITING

    Saint Leonards-on-Sea, East Sussex, TN61HB, United Kingdom

    Contact

  • Local Institution - 0020

    NOT_YET_RECRUITING

    Macquarie Park, New South Wales, 2113, Australia

    Contact

  • Local Institution - 0023

    NOT_YET_RECRUITING

    London, England, W1G 8TA, United Kingdom

    Contact

  • Local Institution - 0024

    NOT_YET_RECRUITING

    London, WC1N3BG, United Kingdom

    Contact

  • Local Institution - 0025

    NOT_YET_RECRUITING

    Montreal, Quebec, H4H 1R3, Canada

    Contact

  • Local Institution - 0027

    NOT_YET_RECRUITING

    Whitby, Ontario, L1N 5S9, Canada

    Contact

  • Local Institution - 0029

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact

  • Local Institution - 0034

    NOT_YET_RECRUITING

    Osaka, 550-0006, Japan

    Contact

  • Local Institution - 0035

    NOT_YET_RECRUITING

    Nankoku-shi, 783-8505, Japan

    Contact

  • Local Institution - 0040

    NOT_YET_RECRUITING

    Suita, Osaka, 565-0871, Japan

    Contact

  • Local Institution - 0042

    NOT_YET_RECRUITING

    Gilbert, Arizona, 85297, United States

    Contact

  • Local Institution - 0043

    NOT_YET_RECRUITING

    Shaker Heights, Ohio, 44122-5288, United States

    Contact

  • Local Institution - 0052

    NOT_YET_RECRUITING

    Nedlands, Western Australia, 6009, Australia

    Contact

  • Local Institution - 0054

    NOT_YET_RECRUITING

    Toronto, Ontario, M6J1H4, Canada

    Contact

  • Local Institution - 1401

    NOT_YET_RECRUITING

    Naples, Florida, 34105, United States

    Contact

Conditions

Explore the condition pages connected to this study.