Could a blood pressure drug slow Alzheimer's? new trial aims to find out

NCT ID NCT06362707

Recruiting now Disease control Sponsor: Helse Stavanger HF Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 trial tests whether fasudil, a drug already used in Japan and China for brain blood vessel spasms, can improve memory and brain function in people with early Alzheimer's disease. Two hundred participants will receive either fasudil or a placebo for 12 months, with regular cognitive tests and brain scans to measure effects. The goal is to see if fasudil can slow the decline in thinking skills and brain metabolism.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Fasudil (a drug approved in Japan and China for vasospasms, now being tested for Alzheimer's)
What this could lead to: If it works, this could point toward a treatment that slows memory loss and brain decline in early Alzheimer's disease.
What could go wrong: This is an early Phase 2 trial with only 200 participants, so results may not apply to everyone. The drug is not yet proven for Alzheimer's, and side effects are still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction follicular lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER DISEASE COGNITIVE DECLINE, MILD

Contacts and locations

Locations

Akershus Hospital:
NOT_YET_RECRUITING

Oslo, Oslo, Norway
Haraldsplass Deaconess Hospital
ENROLLING_BY_INVITATION

Bergen, Vestland, Norway
Haugesund Hospital
NOT_YET_RECRUITING

Haugesund, Rogaland, Norway
St. Olavs Hospital:
NOT_YET_RECRUITING

Trondheim, Trøndelag, Norway
Stavanger University Hospital
RECRUITING

Stavanger, Rogaland, Norway
University Hospital of North Norway
NOT_YET_RECRUITING

Tromsø, Nordland, Norway

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