Could a blood pressure drug slow Alzheimer's? new trial aims to find out

NCT ID NCT06362707

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 trial tests whether fasudil, a drug already used in Japan and China for brain blood vessel spasms, can improve memory and brain function in people with early Alzheimer's disease. Two hundred participants will receive either fasudil or a placebo for 12 months, with regular cognitive tests and brain scans to measure effects. The goal is to see if fasudil can slow the decline in thinking skills and brain metabolism.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fasudil (a drug approved in Japan and China for vasospasms, now being tested for Alzheimer's)

What this could lead to

If it works, this could point toward a treatment that slows memory loss and brain decline in early Alzheimer's disease.

What could go wrong

This is an early Phase 2 trial with only 200 participants, so results may not apply to everyone. The drug is not yet proven for Alzheimer's, and side effects are still being studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction follicular lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Akershus Hospital:

    NOT_YET_RECRUITING

    Oslo, Oslo, Norway

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Haraldsplass Deaconess Hospital

    ENROLLING_BY_INVITATION

    Bergen, Vestland, Norway

  • Haugesund Hospital

    NOT_YET_RECRUITING

    Haugesund, Rogaland, Norway

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Olavs Hospital:

    NOT_YET_RECRUITING

    Trondheim, Trøndelag, Norway

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stavanger University Hospital

    RECRUITING

    Stavanger, Rogaland, Norway

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • University Hospital of North Norway

    NOT_YET_RECRUITING

    Tromsø, Nordland, Norway

    Contact Phone: •••-•••-•••• Email: •••••@•••••