Exercise your brain: simple workouts may ward off Alzheimer's

NCT ID NCT03035851

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether regular aerobic exercise can prevent or slow memory decline in older adults (ages 50-80) who have memory complaints but no dementia. Participants will be randomly assigned to either an aerobic exercise program or a stretching and toning group for six months, with follow-up for another year. The goal is to see if exercise improves thinking skills and brain blood flow, offering a practical way to reduce dementia risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Aerobic exercise

What this could lead to

If it works, this could provide a simple, drug-free way to help prevent Alzheimer's and other dementias in at-risk older adults.

What could go wrong

This is a mid-sized trial testing a behavioral intervention, not a drug. Results may show only modest benefits, and long-term adherence to exercise is challenging.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease dementia Motor Activity subjective cognitive decline

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Calgary

    RECRUITING

    Calgary, Alberta, Canada

    Contact