Exercise your brain: simple workouts may ward off Alzheimer's

NCT ID NCT03035851

Recruiting now Prevention Sponsor: University of Calgary Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether regular aerobic exercise can prevent or slow memory decline in older adults (ages 50-80) who have memory complaints but no dementia. Participants will be randomly assigned to either an aerobic exercise program or a stretching and toning group for six months, with follow-up for another year. The goal is to see if exercise improves thinking skills and brain blood flow, offering a practical way to reduce dementia risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Aerobic exercise
What this could lead to: If it works, this could provide a simple, drug-free way to help prevent Alzheimer's and other dementias in at-risk older adults.
What could go wrong: This is a mid-sized trial testing a behavioral intervention, not a drug. Results may show only modest benefits, and long-term adherence to exercise is challenging.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease dementia Motor Activity subjective cognitive decline

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER DISEASE DEMENTIA

Contacts and locations

Locations

University of Calgary
RECRUITING

Calgary, Alberta, Canada

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