STROKE

This early study tests a brain-computer interface (BCI) for safety in 2 people with severe paralysis from conditions like ALS or spinal cord injury. The device is designed to decode imagined speech and allow control of a computer, helping users communicate and connect. The goal i…

This study compares two treatments for arm and hand spasticity (muscle stiffness) caused by stroke, spinal cord injury, or brain injury. Thirty adults who already get Botox injections will also receive corrective surgery, allowing doctors to see which approach works better for ea…

This study tests whether placing a small tube (stent) in a hardened brain artery during a stroke helps patients recover better than continuing standard clot removal methods. About 500 adults with severe stroke due to a blocked large artery will be randomly assigned to one of the …

This study tests a healthy lifestyle program that has been adapted for Hispanic/Latino people who have had a stroke. The goal is to help participants lose weight and improve health markers like blood sugar and cholesterol. The program includes home weighing scales and in-person c…

This study tests whether taking algae supplements (spirulina or seaweed) for 20 weeks can improve heart health markers and gut bacteria in 150 adults aged 50+ with conditions like heart disease, diabetes, or kidney disease. Participants are randomly assigned to receive algae or a…

This study tests whether a brain stimulation device (deep brain stimulation) combined with physical therapy can improve arm weakness in people who had a stroke 1 to 6 years ago. About 202 participants will receive either the active treatment or a control. The goal is to see if th…

This study tests whether combining electroacupuncture with repetitive transcranial magnetic stimulation (rTMS) improves arm and leg movement after a stroke better than rTMS alone. About 180 adults who had their first stroke 2 weeks to 6 months ago will receive either real or sham…

This study tests a weight-loss program delivered via telehealth for people who have had a stroke. About 94 participants with a BMI of 25 or higher will be randomly assigned to either start the program right away or wait 6 months. The goal is to see if the program helps with weigh…

This study tests a program called SHIFT that helps stroke survivors ages 18-75 who face multiple social challenges (like unstable housing or lack of transportation). The program connects them with community resources to improve their recovery, blood pressure, and thinking skills.…

This study tests whether follow-up care for stroke survivors can be done effectively through video or phone calls with a nurse, instead of in-person clinic visits. About 196 adults who recently had a stroke and own a smartphone will take part. The goal is to see if telecare can r…

This study tests whether combining non-invasive brain stimulation (rTMS) with a special electrical stimulation therapy (CCFES) can improve arm and hand function in people who had a severe stroke at least 6 months ago. The therapy aims to excite the undamaged side of the brain to …

This study tests an experimental drug called DM199 in people who have had a moderate stroke and cannot receive standard clot-removal treatments. The goal is to see if DM199 helps improve recovery and reduce disability. About 728 participants will receive either the drug or a plac…

This study looks at whether adding a blood thinner to standard anti-clotting medication can prevent strokes and other blood clots in people who develop a new irregular heartbeat after heart bypass surgery. About 3,200 adults who had bypass surgery and then a lasting or repeated e…

This study tests a non-invasive treatment called remote ischemic conditioning (RIC) for people recovering from a serious brain bleed (aneurysmal subarachnoid hemorrhage) after surgery. RIC uses a blood pressure cuff on the arm to create brief, harmless blood flow interruptions, w…

This study tests two programs for people recovering from a stroke who are leaving inpatient rehab to go home. Half of the 520 participants will get a stroke education program, and the other half will get a program that helps modify their home environment. The goal is to see which…

This study tests a tool called Savvy to help stroke survivors take their medication regularly. The tool includes short phone exercises, a weekly pill organizer, and text reminders. Researchers will compare medication adherence and blood pressure control between those using Savvy …

This study tests if placing small filters in the carotid arteries (the main blood vessels in the neck) can catch blood clots before they reach the brain and cause a stroke. It involves 2,000 people with atrial fibrillation who have already had a stroke and are taking blood thinne…

This study tests whether starting a special exercise program soon after a stroke can help protect the brain from memory loss and dementia. Researchers will work with 126 people who had a stroke in the last 6 months. They will measure thinking skills and brain blood flow to see if…

This study is testing whether adding the antibiotic minocycline to standard stroke care can improve survival and reduce disability in adults who have had a moderate stroke. About 1,164 participants will be randomly assigned to receive either minocycline pills for five days plus u…

This study looks at whether blood thinners can prevent strokes in people who had a short episode of atrial fibrillation (irregular heartbeat) triggered by stress, such as after surgery or a serious illness. About 2,270 adults with additional stroke risk factors will either take a…

This study tests whether the clot-busting drug tenecteplase can help people who have a stroke caused by a blocked artery in the brain, even when treatment starts 24 to 72 hours after symptoms begin. About 330 adults with moderate to severe stroke will receive either tenecteplase …

This study tests a new AI system that guides stroke survivors through arm exercises at home. About 192 people who had a stroke at least 6 months ago will take part. The goal is to see if the AI helps improve arm movement better than standard care or exercises without AI.

This study tests a new, less invasive surgery to remove blood clots from the brain within 8 hours of a stroke caused by bleeding. About 240 adults with large brain bleeds will be randomly assigned to either the new surgery or standard medical care. The goal is to see if the surge…

This study tests whether a drug called clevidipine can lower blood pressure quickly and keep it stable in people having a bleeding stroke. About 1,000 adults with high blood pressure and stroke symptoms will receive either clevidipine or another IV blood pressure medicine. The go…

This study tests a pharmacy-led program to help low-income patients with chronic conditions like diabetes and heart disease take their medications after leaving the hospital. The program provides free medications, bedside delivery, and health coaches to help with follow-up care. …

This study tests whether injecting a clot-dissolving drug directly into the blocked brain artery can improve recovery for people with a medium vessel stroke. About 282 adults whose stroke is caused by a blockage in a medium-sized brain artery will receive either the drug injectio…

This early study tests a device that sends mild electrical pulses to the spinal cord and limbs to help people with paralysis or weakness from spinal cord injury, stroke, or other nerve damage. Up to 64 participants will attend up to 5 sessions per week for a year, performing task…

This study compares two common procedures (radiofrequency and cryoablation) for treating persistent atrial fibrillation, a heart condition that raises stroke risk. Researchers will track 158 adults over 24 months to see which method better prevents strokes, blood clots, and repea…

This study tests a smartphone app that uses virtual and augmented reality games to help people who had a stroke improve arm movement and thinking skills at home. Seventy adults who are at least three months past their stroke will use the app for six weeks or receive standard care…

This study tests a new device called CLAAS that closes a small pouch in the heart to prevent strokes in people with atrial fibrillation (an irregular heartbeat). About 1,600 participants will be randomly assigned to get either the new device or an existing one, and they will be f…

This study tests whether stroke patients who take FXa inhibitor blood thinners can safely receive a standard clot-busting drug (IVT) without raising their risk of brain bleeding. Current guidelines deny IVT to these patients due to bleeding concerns, but new evidence suggests it …

This study tests whether two drugs, colchicine and ticagrelor, can reduce inflammation and lower the risk of another stroke or heart attack in people who have already had a stroke. About 2,800 high-risk participants will take these medications alongside standard care. The goal is…

This study tests whether a high-dose, high-intensity neurorehabilitation program is feasible for stroke patients. About 120 adults with stroke will receive 300 minutes of active, technology-supported training each week, in addition to standard care, across inpatient, outpatient, …

This study looks at whether carefully adjusting blood pressure during clot-busting treatment for stroke can lower the risk of dangerous bleeding in the brain. About 340 adults aged 18 to 80 with acute ischemic stroke and high blood pressure will take part. Researchers will compar…

This study tests whether Diroximel Fumarate, a drug already used for multiple sclerosis, can reduce harmful brain swelling that often occurs after a bleeding stroke. The trial will enroll 192 adults who have had a stroke, giving the drug within 48 hours of symptoms. The goal is t…

This study tests whether using a balloon guide catheter that temporarily stops blood flow helps doctors remove clots more effectively in people having a stroke caused by a blocked carotid artery. About 364 adults will be randomly assigned to receive either the balloon catheter or…

This study tests whether an investigational drug called Dimephosphon can improve recovery in people who have had an acute ischemic stroke (a stroke caused by a blood clot). The trial involves 184 adults aged 35-80 who receive either Dimephosphon or a placebo within 24-72 hours of…

This study tests whether a robotic exoskeleton (Gloreha Sinfonia) added to standard therapy helps people who had a stroke within the past 90 days regain arm movement better than standard therapy alone. About 130 adults with mild to moderate arm weakness will be randomly assigned …

This study looks at people who already have a deep brain stimulation (DBS) device for movement problems like tremor or stroke. Researchers will adjust the device's settings and then test how well participants can move their hands, speak, swallow, and make facial expressions. The …

This study looks at whether the blood thinner warfarin is safe and effective for preventing strokes in people with kidney failure who are on dialysis and have atrial fibrillation (an irregular heartbeat). About 718 adults will be randomly assigned to take warfarin or not, and res…

This study tests whether a cardiac rehabilitation program—normally used for heart patients—can improve recovery in 150 stroke survivors. Participants will receive standard stroke care plus cardiac rehab. Researchers will measure walking ability, daily function, hospital readmissi…

This study looks at whether a procedure called endovascular thrombectomy (EVT) can help people who have a stroke but already had a moderate-to-severe disability before the stroke. About 1,060 adults with a large blood vessel blockage in the brain will be randomly assigned to get …

This study looks at whether losing weight and exercising can improve walking ability and emotional well-being in veterans who are overweight and have had a stroke. About 130 participants will be assigned to a diet program, a diet-plus-exercise program, or a waitlist. The goal is …

This study tests whether using remote-controlled CT scans with live video guidance from stroke experts can help smaller hospitals treat stroke patients faster. About 52 adults with suspected stroke will be enrolled. The goal is to see if this approach reduces the time to give clo…

This study tests a device called SSMD to see if it helps adults with arm weakness from stroke or traumatic brain injury. About 150 participants will get either SSMD therapy plus standard rehab or standard electrical stimulation plus rehab. The goal is to measure improvements in a…

This study tests whether closing a small hole in the heart (called PFO) with a special device, along with blood-thinning medication, can help prevent another stroke in people who already had a stroke of unknown cause. About 636 participants will receive the device and be followed…

This study tests whether keeping blood pressure very low (below 120 mmHg) after a stroke procedure called thrombectomy helps patients recover better than standard care (140-180 mmHg). About 910 adults who had a major stroke will be randomly assigned to one of the two blood pressu…

This study looks at whether giving a powerful cholesterol-lowering medicine (a PCSK9 inhibitor) before a procedure to remove a blood clot in the brain can improve recovery for people having a major stroke. About 652 adults who are scheduled for this emergency procedure will be ra…

This study looks at two ways to help people who have had a stroke lower their blood pressure. One way is checking blood pressure at home. The other adds group medical visits where people learn together. The goal is to see if combining both methods works better to prevent another …

This early study tests a wireless brain implant from Neuralink that aims to let people with severe paralysis or ALS communicate just by thinking. The device is placed in the brain by a robot. The study will check if it is safe and works for 6 adults who cannot speak or use their …

This study tests if a non-invasive nerve stimulation (taVNS) combined with occupational therapy can help people who had a stroke more than 6 months ago improve arm and hand movement. The treatment is given through the skin on the neck, no surgery needed. 60 adults with arm weakne…

This study tests whether a simple set of treatments—lowering blood pressure, controlling fever, and managing blood sugar—can help people recover better after a brain bleed (intracerebral hemorrhage). About 3,500 adults in Sweden and Australia will receive either the care bundle o…

This study compares two treatments for people having a small type of stroke called a lacunar stroke. One group gets a standard clot-busting medicine through an IV, while the other takes a combination of antiplatelet pills (similar to aspirin). The goal is to see if the pills work…

This study looks at whether an ultrasound of the optic nerve can help doctors quickly detect brain swelling and inflammation in ICU patients with conditions like meningitis, stroke, or brain tumors. Researchers will measure the optic nerve sheath diameter and compare it with stan…

This study tests if a more precise, goal-directed Valsalva maneuver (using a pressure gauge) finds a small heart hole called PFO better than the usual self-directed method (just bearing down). About 488 people who need a heart ultrasound after a stroke will be asked to do both ma…

This study tests a small, smart sensor that listens to chest sounds to help doctors screen for pneumonia in people who are at high risk—specifically stroke patients and those with kidney failure on dialysis. The sensor detects abnormal sounds that might mean fluid or infection in…

This study tests a portable EEG device called StrokePointer that ambulance crews can use on people with suspected stroke. The goal is to see if it can accurately identify patients with a large vessel occlusion stroke, who need to go directly to a hospital that offers a specialize…

This study tests whether a detailed CT scan (multimodal CT) can more accurately identify the blocked artery in people having a stroke caused by a medium-sized vessel blockage. Researchers will compare the accuracy of this advanced scan against standard CT scans. The goal is to he…

This study tests whether a radioactive tracer called Florbetaben, used with a PET scan, can detect inflamed plaques in the arteries of people who recently had a heart attack or stroke. About 30 participants will receive the tracer and undergo imaging to see if it highlights dange…

This study aims to create a quick blood test to tell if a stroke is caused by bleeding or a clot, helping doctors give the right treatment faster. Researchers will test a protein called GFAP in 527 adults with suspected stroke symptoms. The goal is to improve early diagnosis and …

This study tests a music-inspired program called Music4Health to help prevent high blood pressure and stroke in Nigeria. About 1,400 youth (ages 14-24) and their caregivers (ages 40+) will take part. The program uses community-designed music and campaigns to lower blood pressure …

This study looks at whether using a 7-day heart monitor can help find hidden atrial fibrillation (an irregular heartbeat) in people with high NT-proBNP levels, a sign of heart strain. 4,000 adults without known AF will be split into two groups: one gets the monitor, the other doe…

This study tests whether a nurse-led health education program for first-time stroke patients and their family caregivers can lower the chance of having another stroke. The program focuses on teaching about risk factors and healthy lifestyle changes. Researchers will compare strok…

This study tests whether a daily medicine called hydroxyurea can prevent strokes in children with sickle cell anemia who are at high risk. About 220 children in Nigeria will receive low or moderate doses of the drug and be monitored for strokes or mini-strokes. The goal is to see…

This study tests a new rehabilitation approach called NICE for people who have had a stroke and have arm weakness. The method uses a computer screen to guide patients to activate specific muscle groups, aiming to improve arm movement and coordination. About 48 adults aged 21-80 w…

This study tests whether adding rhythmic music to treadmill walking with thinking tasks helps people who had a stroke walk better in their community. About 90 adults who had a stroke at least 6 months ago will be assigned to one of three training groups. The goal is to see if the…

This study tests whether the antidepressant escitalopram can make language therapy work better for people with aphasia (trouble speaking or understanding language) after a stroke. About 88 adults who had a stroke within the past 3 months will receive either escitalopram or a plac…

This study looks at whether high-intensity interval training (HIIT) on a recumbent stepper can improve muscle power in people who had a stroke 1-5 years ago. 66 participants will be randomly assigned to HIIT, moderate exercise, or stretching for 12 weeks. Researchers will measure…

This study tests whether adding visual biofeedback to standard swallowing exercises and electrical stimulation helps people who have trouble swallowing after a stroke. About 34 adults who had a stroke within the last 6 months will be split into two groups: one gets visual feedbac…

This study is testing whether adding sensory training to a standard arm therapy (Constraint-Induced Movement therapy) helps stroke survivors use their affected arm and hand more in daily life. The therapy involves intensive practice and temporarily restraining the less-affected a…

This study tests whether combining virtual reality (VR) exercises with a gentle brain stimulation technique (tDCS) can improve arm and hand movement in people who had a stroke at least three months ago. About 100 adults will be assigned to different therapy groups to see which ap…

This study tests whether adding augmented reality (AR) or virtual reality (VR) to treadmill training helps stroke survivors improve their balance and walking. 66 adults who have had a stroke will be split into three groups: one using VR, one using AR, and a control group doing ho…

This study tests if a less invasive freezing technique (cryoneurotomy) works as well as surgery to reduce foot stiffness in people who have had a stroke. About 114 adults with chronic foot spasticity will be randomly assigned to one of the two treatments. The goal is to see if th…

This study tests whether adding action observation (watching movements) and motor imagery (imagining movements) to standard physical therapy can improve balance, daily function, and quality of life for people who had a stroke within the last year. About 56 participants will be ra…

This study tests a fast form of brain stimulation (rTMS) to help people who feel apathetic after a stroke. Apathy means losing motivation and interest in daily life. The treatment targets a brain area linked to motivation and is given over a short period. The goal is to see if it…

This study tests a digital program on an iPad that combines brain-training games with learning practical thinking strategies. The goal is to see if it can improve mood, memory, and daily function in people who had a stroke at least 6 months ago. Researchers will enroll 70 adults …

This study tests a small-group, video-based self-management program for people who had a mild or moderate stroke within the last 6 months. The goal is to help participants improve their ability to perform daily activities, feel more confident, and enhance their quality of life. T…

This early-stage study tests a new exercise called CUped, which uses a robotic device to help stroke survivors recover leg movement and improve walking. The goal is to see if it is safe, tolerable, and effective for 12 adults who have had a stroke. The exercise is done while sitt…

This study tests whether a robotic device called Pablo Tyromotion can improve arm and hand function in people who had a stroke. 120 adults aged 45-80 with mild to moderate arm weakness will use the device in rehab sessions. The goal is to see if this technology helps them regain …

This study tests a wrist-worn sensor system called StrokeWear that reminds and encourages stroke survivors to use their weaker arm during daily activities at home. About 88 people who had a stroke 1 to 6 months ago will either use the sensor with a home exercise program or follow…

This study explores whether listening to music for one hour each day can improve emotional well-being in people who have had a stroke. Sixty adults aged 50 to 90 who had a stroke at least six months ago will be randomly assigned to listen to music or an audiobook for four weeks. …

This study tests whether adding virtual reality to brain-computer interface training helps stroke survivors regain arm and hand function. Twelve adults who had a stroke 6 to 24 months ago will try both standard BCI training and BCI with VR, each for 6 weeks. Researchers will meas…

This study tests whether mild electrical stimulation applied to the spinal cord can help people who had a stroke move their arm and hand better. About 20 adults with weakness on one side will receive a temporary implant and be measured for changes in movement, sensation, and qual…

This study tests whether a mild electrical current applied to the scalp (tDCS) can improve arm recovery in people who recently had a stroke. Fifty adults with severe arm weakness will receive either real or fake (sham) stimulation during rehab. The goal is to see if the real stim…

This study tests whether combining a gentle brain stimulation technique (tDCS) with special training that challenges both walking and thinking can help stroke survivors improve their ability to do two things at once. Researchers will measure walking speed, mental performance, and…

This study tests whether adding extra arm-hand exercises to standard care helps stroke patients regain arm and hand function. Eighty people who had a stroke will be split into two groups: one gets the extra arm-hand therapy, the other gets extra leg exercises. Researchers will ch…

This study looks at whether a 15-week program combining weight loss and exercise can improve walking and daily life for veterans who have had a stroke and are overweight. About 99 participants will take part. The goal is to see if this lifestyle approach helps with common problem…

This study tests whether virtual reality (VR) training that looks like a real home can help stroke survivors improve arm and hand function. About 86 people who had a stroke 1 to 6 months ago will be split into three groups: VR-based task training, standard task training, or usual…

This study tests whether a robotic leg brace (exoskeleton) can improve walking and daily function in 50 stroke survivors during inpatient rehab. Participants will use the device during therapy, and researchers will measure changes in walking distance, muscle stiffness, and indepe…

This study tests whether using a mobile breathing trainer (AiroFit PRO™) for 6 weeks can improve lung function, muscle strength, and quality of life in people with hemiplegia (weakness on one side) after a stroke. About 54 adults who are at least 3 months post-stroke will be rand…

This study tests whether adding intensive virtual reality-based balance and gait training to standard physical therapy helps people who had a stroke within the last six months. About 48 adults will be randomly assigned to either standard rehab alone or standard rehab plus VR trai…

This study compares two ways of making ankle-foot braces (AFOs) for people with leg weakness from conditions like cerebral palsy, stroke, or spinal cord injury. The traditional method uses a plaster cast, while the newer method uses 3D scanning and printing. Researchers want to s…

This study tests whether numbing a nerve in the arm or leg can reduce the severe, hard-to-treat pain some people feel after a stroke. Researchers will give 36 adults either a local anesthetic (lidocaine or levobupivacaine) or a placebo injection, then measure pain changes. The go…

This study looks at whether a twice-weekly exercise program can improve sleep quality in people who had a stroke at least a year ago and currently have poor sleep. About 62 adults aged 55 and older will take part in a 6-month program. The goal is to see if exercise helps with sle…

This study is testing a new robotic ankle exoskeleton designed to help people who have had a stroke walk more easily. About 15 stroke survivors will wear the device while walking on a treadmill, overground, and on stairs or ramps. Researchers will compare walking with the powered…

This study tests a new exercise program called Task-Oriented Circuit Training (TOCT) for people who have had a stroke. The program uses 15 different exercise stations to improve arm and hand movement. Researchers will measure dexterity, grip strength, and coordination in 24 adult…

This study tests whether a technique called biofeedback can improve arm and hand function in people who have had a stroke. Researchers will enroll 120 adults aged 45-80 who have some arm weakness but can still grip. Participants will do rehabilitation exercises while receiving re…

This study tests a wrist-worn sensor system called StrokeWear that reminds and encourages stroke survivors to use their weaker arm during daily activities at home. 32 adults who had a stroke 6 months to 5 years ago will either use the sensor with a home exercise program or follow…

This study tests a low-cost shoe that changes friction to help people with foot drop after a stroke walk better. About 50 adults who are at least 3 months past their stroke will use the shoe at home. The goal is to see if it improves walking speed and balance.

This study tests whether a non-invasive treatment called extracorporeal shock wave therapy (ESWT) can reduce muscle stiffness (spasticity) in the wrist of people who have had a stroke. About 32 adults aged 35-65 who had a stroke more than 6 months ago will receive either ESWT or …

This study tests two different technology-based therapies—robot-assisted walking training and visual feedback balance training—to see which helps stroke patients improve their balance and walking ability. About 60 adults who had a stroke will participate in 4 weeks of therapy. Th…

This study looks at two ways to help people who have had a stroke become more active. It compares a structured exercise program in a special facility to a self-guided program at home. The goal is to see which approach helps increase daily steps and improve quality of life. The st…

This study tests whether mild electrical stimulation of the vagus nerve (through the ear or neck) can improve arm movement, thinking skills, and quality of life when added to standard therapy. About 54 adults who had a stroke 3–6 months ago will receive either ear or neck stimula…

This study tests whether a gentle magnetic pulse to the brain (TMS) combined with language therapy can improve word-finding in people who have trouble speaking after a stroke. About 50 adults who had a left-brain stroke at least one month ago will take part. The goal is to see if…

This study tests whether a gentle electrical current applied to the brain can make speech therapy more effective for people with long-term aphasia after a stroke. About 50 participants who had a stroke at least 6 months ago will receive either real or fake stimulation during 15 t…

This study tests a gentle ultrasound treatment on the brain to see if it can improve arm movement and motor learning in people who had a stroke at least 6 months ago. Researchers will try different power levels and timing to find the best settings. 24 adults with arm weakness wil…

This study tests a program that combines mindfulness exercises with dual-task training (doing two things at once) to help people who have mild memory or thinking problems after a stroke. The goal is to see if this combined approach improves both cognitive function and physical pe…

This study is testing a wearable exoskeleton designed to improve walking balance in people who have had a stroke. About 21 participants who had a stroke at least 6 months ago and have trouble walking will try the device on a treadmill under different conditions. The goal is to se…

This study tests a new way to help people who had a stroke improve their balance. Many stroke survivors have balance problems because their senses don't work as well. The study uses small, painless vibrations on the skin to give the brain extra information about body position. 36…

This study compares two types of physical therapy exercises for people who had a stroke within the last six months. One group will do core strengthening with special pelvic movements, while the other group does standard trunk exercises. The goal is to see which approach better im…

This study compares doing rehab exercises at home via video (tele-rehabilitation) versus going to a clinic for stroke survivors with mild to moderate thinking problems. About 32 adults aged 50-80 who had a stroke will participate. The goal is to see if remote therapy is as effect…

This study tests whether adding gentle vibration to hand exercises helps stroke survivors regain hand function, feeling, and reduce muscle stiffness. About 38 people who had a stroke at least 3 months ago will be randomly assigned to either vibration-plus-exercise or exercise alo…

This study looks at whether moderate or high-intensity walking exercise is better for improving walking in people who had a stroke at least 6 months ago. About 156 participants will be randomly assigned to one of two exercise programs, each done with a physical therapist for 45 m…

This study tests a web-based rehab program for stroke survivors and their care partners (family members). The program focuses on problem-solving and arm exercises at home to improve the survivor's arm use and social participation while also supporting the caregiver's well-being. …

This study tests a new way to help people who lost part of their vision after a stroke. Participants do daily eye exercises with sounds and lights, combined with gentle brain stimulation. The goal is to see if this can improve their visual field and daily activities.

This study tests a task-specific self-rehabilitation program (TASSRET) for stroke survivors living at home with no access to physiotherapy. Fifty Hausa-speaking adults will use either a video or manual guide to improve their movement, balance, and quality of life. The goal is to …

This study tests whether using a soft robotic hand together with electrical stimulation can help stroke survivors regain hand function better than either therapy alone. About 64 people who had a stroke 3-6 months ago will take part in an 8-week program. The goal is to improve gri…

This study looks at two different ways to decide when it's safe to remove the breathing tube from stroke patients. One method uses a special valve that lets patients speak, while the other is the standard approach of capping the tube. The goal is to see which method leads to more…

This study tests a robotic exoskeleton that limits certain arm and trunk movements to help people recovering from a stroke regain better control of their arm. The goal is to see if this approach reduces the use of compensatory movements and improves natural arm function. The tria…

This study compares two modern therapies—mirror therapy and virtual reality (VR)—to see which one better improves arm function in people with hemiplegia (paralysis on one side) after a stroke. Forty-two adults aged 18 to 75 who had a stroke 6 to 12 months ago will be randomly ass…

This study tests a therapy called Constraint-Induced Movement Therapy for adults who had a stroke at least 6 months ago and have mild weakness in one arm. The therapy involves daily training sessions to improve arm use, along with techniques to encourage using the weaker hand in …

This study looks at whether playing music during routine nursing care, like bed baths, can help stroke patients feel more comfortable in the intensive care unit. About 102 adults who recently had a stroke will rate their comfort using a simple face scale. The goal is to see if mu…

This study tests whether adding a gentle electrical stimulation to arm cycling exercises helps people who had a stroke within the last 6 months. 24 participants will do standard rehab plus either regular arm cycling or arm cycling with electrical stimulation. The goal is to see i…

This study tests whether an over-the-counter supplement called MitoQ and a technique called ischemic conditioning (briefly restricting blood flow to the arm) can improve blood vessel health in 30 stroke survivors. Participants will have their blood vessel function measured before…

This study looks at whether a gentle nerve stimulation (tVNS) combined with a hand therapy program (mCIMT) can help people who had a stroke more than 6 months ago improve arm movement, thinking, and daily life. About 50 participants will be split into two groups: one gets both tr…

This study tests a new rehabilitation program called ACES, which combines acceptance and commitment therapy with strategy training, to help people who have had a stroke rejoin social activities. About 54 chronic stroke survivors living in the community will take part. Researchers…

This study is testing a new soft robotic glove designed to help people who have had a stroke regain movement in their wrist and hand. Sixty stroke survivors will be split into three groups to compare the robotic glove with standard therapy. The glove uses muscle signals to sense …

This study tests whether a gentle, non-invasive electrical stimulation on the ear (trans-auricular vagus nerve stimulation) can help people recovering from a stroke regain arm movement faster. About 48 adults who had a stroke within the last 6 months will receive either real or f…

This study tests if combining two types of nerve stimulation can improve arm and hand function in people who had a stroke at least 6 months ago. Researchers will compare the combined treatment to a placebo in 120 adults aged 55-75. The goal is to see if this safe, non-invasive ap…

This study tests whether a combination of transcranial magnetic stimulation (TMS) and speech-language therapy can improve language skills in people with mild aphasia after a stroke. Researchers will compare real TMS to a fake version to see if the treatment works. Participants wi…

This study looks at whether combining two types of attention-focus instructions (internal and external) in the same session works better than using them one after the other for improving arm and hand function in people who had a stroke within the past six months. About 36 adults …

This study compares three rehabilitation approaches for people recovering from stroke: mirror therapy, cognitive orientation to daily occupational performance (CO-OP), and conventional occupational therapy. 45 adults with subacute or chronic stroke will receive one of these thera…

This pilot study tests whether combining balance training with a mild electrical stimulation to the spinal cord can improve balance and reduce falls in people who had a stroke over a year ago. Sixteen participants will be randomly assigned to receive either real or sham stimulati…

This study tests a digital speech therapy app called Zenicom for people who have trouble speaking after a recent stroke. About 20 adults with aphasia will either do standard speech therapy alone or add the app for two weeks. The goal is to see if the app safely improves language …

This study tests a device implanted in the body to help people who have had a stroke walk more easily. It includes 6 participants who are at least 6 months past their stroke and have trouble walking. The device is set up and tested over several months to see if it improves walkin…

This study tests whether adding virtual reality therapy to standard rehabilitation and action observation therapy can improve arm and hand function in people who had a stroke within the past 6 weeks to 6 months. 38 participants will be randomly assigned to receive either standard…

This study tests whether watching videos of functional actions (like walking) combined with rhythmic sounds can improve balance and walking in people who have had a stroke. Forty participants will either receive standard therapy or watch these videos with music for 30 minutes a d…

This study tests a home-based occupational therapy program that uses activity tracking, coaching, and video calls to help stroke survivors improve daily functioning. Researchers will compare this approach to usual care in 171 older adults leaving geriatric rehab. The goal is to s…

This study explores whether hypnosis can help people with stroke, traumatic brain injury, or multiple sclerosis improve their attention and reduce fatigue. Researchers will use EEG to monitor brain activity during hypnosis sessions. The goal is to see if this approach is practica…

This study tests whether a non-invasive brain stimulation technique called iTBS can improve balance, walking, and leg movement in people who had a stroke more than six months ago. Researchers will also look at how the brain changes during recovery. The trial involves 56 adults wi…

This study compares two high-tech devices—the Lokomat exoskeleton and the C-Mill treadmill—to see which one helps stroke survivors improve their walking and quality of life. About 40 adults who have had a stroke will use one of the devices during rehab. Researchers will check the…

This study tests whether a gentle brain stimulation technique called tDCS, combined with health education and aerobic exercise, can ease the crushing fatigue many people feel after a stroke. Researchers will enroll 54 adults who had a first stroke within the past 45 days and repo…

This study compares two ways of using a robot to help people who had a stroke more than 3 months ago regain arm and hand function. About 72 adults aged 20-75 will receive 18 therapy sessions over 6 weeks. The goal is to see which robotic training sequence works better for improvi…

This study tests whether adding a vibrating device (Vibramoov®) to robotic walking training (Lokomat®) helps stroke patients walk better than robotic training alone. Forty adults who had a stroke at least 3 months ago will take part in a 4-week rehab program. The goal is to see i…

This study tests a 6-week online program that combines personal skill-building with inclusive volunteering to help young stroke survivors (ages 18-64) improve their ability to work. 160 participants will be randomly assigned to either the program plus usual care or usual care alo…

This study looks at whether the number of high-intensity walking training sessions per week affects walking ability in people who had a stroke at least 6 months ago. 40 participants will be assigned to either high or low frequency training, plus a home walking program. The goal i…

This study tests whether a smartphone app, used alongside standard care, can help people who have had a stroke recover their ability to swallow safely. About 74 adults with swallowing difficulties after a stroke will either use the app or receive usual care alone. The goal is to …

This study tests a special hand exercise program for children aged 7 to 12 who had a stroke. The program uses many repetitions and strength-building activities to improve how well they can use their affected arm and hand. Researchers will measure changes in hand ability using a q…

This study compares two language therapies for people with aphasia (trouble speaking or understanding language) after a stroke. One therapy aims to stimulate the right side of the brain to improve storytelling and conversation, while the other focuses on word-finding. The trial i…

This study tests a smart wearable device called gaitQ that uses cues to help people with long-term movement conditions like Parkinson's disease, stroke, multiple sclerosis, and arthritis walk better. Researchers will measure walking speed, step length, and safety in 150 participa…

This study tests two ways of using action observation therapy to improve swallowing in stroke patients who have trouble eating and drinking. 90 participants will either get standard care, watch videos of swallowing, or observe real-life eating by family members, then imitate the …

This study tests whether personalized brain stimulation (rTMS) can improve arm and hand movement in people who recently had a stroke. About 120 participants will receive either standard or customized stimulation based on their individual brain reserve. The goal is to see if a tai…

This study looks at whether injecting Xeomin® into the arm can improve walking and mobility in adults who have had a stroke. About 20 people with arm and leg stiffness will be tested before and 4-6 weeks after the injection using simple walking tests. The goal is to see if treati…

This study tests whether combining Tai Chi movements with a robotic arm can help people who have had a stroke regain better use of their affected arm. About 120 adults who had a first stroke within the past year will be randomly assigned to either robot-assisted Tai Chi or standa…

This study tests whether having a trained peer coach (another stroke survivor) can improve well-being and quality of life after a stroke. About 20 participants will either receive coaching sessions or deliver them as coaches. Researchers will measure mental health, hope, and dail…

This study tests a new rehabilitation method for people who lost part of their vision due to a stroke. The approach combines gentle electrical brain stimulation with visual exercises using moving images, sometimes in virtual reality. The goal is to see if this can speed up and im…

This study tests a new program that combines virtual reality (VR) training with real-world practice to help stroke survivors walk more confidently and participate in community activities. Forty chronic stroke survivors will use VR goggles to navigate a virtual shopping mall and s…

This study tests whether speech therapy delivered remotely (via video) works as well as in-person therapy for people with aphasia after a stroke. About 100 adults who had a stroke at least a year ago will receive either remote or in-clinic therapy. The goal is to see if both appr…

This study tests whether a special virtual reality program that stimulates multiple senses can help people who have had a stroke improve their movement and thinking. Researchers will compare the VR therapy to standard care in 40 adults aged 18-85 who had their first stroke. The g…

This study looks at whether high-intensity interval training (HIIT) can help reduce fatigue in people who have had a stroke. Sixty adults aged 40-80 who have had a stroke in the past 6 months to 5 years will be placed into one of three groups: HIIT, moderate exercise, or stretchi…

This small pilot study is testing whether combining two non-invasive treatments—brain stimulation (tDCS) and muscle stimulation (FES)—can help people who had a stroke at least six months ago regain better control of their hand. The study involves 15 participants and measures chan…

This study tests whether a mild electrical current applied to the back of the head (cerebellar tDCS) can improve language therapy for people with aphasia after a stroke. About 60 adults who had a stroke at least 6 months ago and have trouble naming objects will receive either rea…

This study tests whether adding visual-motor training (exercises that coordinate what you see with how you move) to standard physiotherapy can improve arm and hand function in people who have had a stroke. Researchers will enroll 38 adults who are at least 6 months past their fir…

This study is testing a wearable device called a myoelectric-computer interface (MCI) to help people who have had a stroke improve arm movement. The device works by giving feedback on individual muscle activations to reduce abnormal co-contractions that limit coordination. The st…

This study tests whether adding robotic exoskeletons and virtual or augmented reality to treadmill training helps people who have had a stroke improve their walking and daily independence. Researchers will compare different training methods in 80 participants to see which works b…

This study tests whether a spinal cord stimulator, combined with physical therapy, can help people who had a stroke more than 6 months ago and still have weakness in one arm and hand. Participants first do 6 weeks of physical therapy alone, then get a spinal cord stimulator impla…

This study tests a new type of stroke rehabilitation that combines mirror therapy with other techniques to help people who had a stroke at least 3 months ago. The goal is to improve arm movement, strength, and daily life skills. About 81 adults aged 20-80 will participate, and th…

This study tests whether a non-invasive nerve stimulation technique (taVNS) combined with robot-assisted arm training can improve arm movement, breathing strength, and quality of life in people who had a stroke at least six months ago. Thirty adults with moderate to severe arm we…

This study looks at whether a hands-on technique called thoracic spinal manipulation can improve balance, reduce fall risk, and increase upper back movement in people who have had a stroke. Researchers will enroll 52 adults aged 40 to 75 who have had a chronic stroke and can stan…

This study tests whether a non-invasive magnetic brain stimulation technique called rTMS can reduce fatigue in people who had a stroke more than six months ago. About 60 participants will receive rTMS, and researchers will track changes in fatigue, mood, and thinking. The goal is…

This study tests whether a tongue endurance exercise program can improve swallowing in adults who have trouble swallowing after a stroke. About 70 people will be randomly assigned to do either the tongue exercises or a sham therapy at home for 8 weeks. Researchers will measure ch…

This study tests whether a brain-training technique called EEG neurofeedback can improve arm movement when started soon after a stroke. About 40 adults who had a stroke within the past 3 weeks will either get real or fake neurofeedback alongside standard rehab. The goal is to see…

This study tests a 6-month nurse-led rehabilitation program for stroke patients in Bangladesh after they leave the hospital. The program includes a team of nurses, physical therapists, and occupational therapists to help with self-care and using assistive devices. Researchers wil…

After a stroke, some people have trouble paying attention to one side of their body or space, called neglect. This study tests a special training that teaches people to be more aware of this problem and use strategies to cope. Researchers will work with 45 adults who have had a s…

This study tests a new approach to help people with aphasia (trouble finding words after a stroke) remember words better and use them in everyday life. Researchers will compare different practice schedules to see which one helps words stick longer. The study involves 32 adults wi…

This study looks at whether adding mindfulness exercises to neuromuscular stimulation can improve lung function, physical abilities, and stress levels in people recovering from a stroke. About 60 adults aged 50 to 65 will take part. One group gets both treatments, the other gets …

This study tests a new hand therapy for people who have lost hand function after a stroke. 30 participants in the early recovery phase will either do standard rehab or use a special brain-computer interface that turns their concentration into virtual hand movements. The goal is t…

This study tests whether exercise plans tailored by data from wearable sensors can help people with chronic stroke walk better. Fifty-two participants will do 12 supervised sessions over six weeks. Researchers will measure changes in gait, muscle activity, and balance to see if t…

This study tests whether a 12-week home telerehabilitation program using the MindMotion GO device can help stroke patients improve motor skills. It involves 51 adults who had a stroke more than 30 days ago and still have arm or leg weakness. The program provides 300 minutes of we…

This study looks at a new way to treat shoulder pain that often happens after a stroke. The pain is thought to be caused by a buildup of a natural substance called hyaluronic acid in the muscles, making them stiff and painful. Researchers will give injections to reduce this build…

This study tests a mobile app called MAYA that provides cognitive behavioral therapy (CBT) to help adults aged 40-79 who have had a stroke and are dealing with anxiety or depression. The goal is to see if the app is easy to use and acceptable to patients. Ten participants will us…

This study tests whether a 12-week seated Tai Chi program can improve thinking, arm function, balance, and mood in chronic stroke survivors with memory or attention problems. About 176 participants (88 stroke survivors and their caregivers) will be randomly assigned to either the…

This study is testing whether virtual reality (VR) and mixed reality (MR) games can help stroke survivors improve arm and hand function. About 45 adults who had a stroke will try these high-tech mirror therapy systems or standard therapy. The goal is to see if the VR/MR approache…

This study tests whether a new virtual reality therapy can help people who had a stroke more than 6 months ago improve arm function. 44 participants will compare two VR approaches that use mirror therapy and task practice. The goal is to see which method better boosts motor skill…

This study is testing a suit called Mollii that uses mild electrical pulses to see if it helps people with stroke or multiple sclerosis move more easily and improve their daily life. About 40 participants will wear either the active suit or a placebo version to compare results. T…

This study is testing a home-based robot that stretches and exercises the ankle, combined with mild electrical stimulation to activate leg muscles, for people who had a stroke at least 6 months ago. The goal is to improve leg movement, reduce stiffness, and make walking easier. A…

This study is testing whether virtual reality exercises can help people who have trouble paying attention after a brain injury, such as from a stroke, accident, or tumor. The researchers will enroll 135 adults and use fun, game-like VR tasks to train attention and thinking skills…

This study tests a procedure called cryoneurolysis, which uses cold to freeze specific nerves in the shoulder, to see if it relieves pain and improves movement in people with spasticity (muscle tightness) after stroke, brain injury, or multiple sclerosis. It compares the freezing…

This study tests whether a behavior change program with personalized exercise plans can help stroke survivors become more physically active. Researchers will compare a group that gets up to 6 coaching sessions (in-person and by phone/video) plus a custom activity plan, to a group…

This study looks at three different hand therapies—mirror therapy, brain stimulation, and robotic hand training—added to standard rehab for stroke patients. The goal is to see which one works best for improving arm movement, reducing pain, and boosting quality of life. About 120 …

This study is testing whether a precise vibration system can improve muscle strength, coordination, and movement, and reduce pain in older adults and stroke survivors. Researchers will recruit 80 participants to try the vibration exercises and measure changes in strength, balance…

This study tests whether a non-invasive treatment called extracorporeal shockwave therapy can improve arm function and reduce muscle tightness in people who had a stroke six months ago. Fifty adults aged 25 to 65 will receive either the shockwave treatment or a placebo. The goal …

This study compares robotic gait training to usual physical therapy for people recovering from a stroke. Researchers want to see if using a robotic exoskeleton early in rehab helps patients walk faster and more independently. The study involves 54 adults aged 18-85 who are in inp…

This study tests whether a technique called biofeedback can improve swallowing in people who have had a stroke. One hundred participants will either receive standard swallowing therapy or therapy with a screen that shows their swallowing muscles in real time. The goal is to see i…

This study tests a home-based telerehabilitation program for stroke survivors who did not receive outpatient therapy. Two hundred participants will use wearable sensors and game-like exercises guided remotely by therapists. The goal is to improve arm and hand movement and make re…

This study looks at whether adding electrical muscle stimulation or special sound beats to mirror therapy can improve leg function in people who had a stroke at least 6 months ago. About 72 adults aged 20-80 will be enrolled. The goal is to see which combination works best for mo…

This study looks at whether adding Vojta therapy—a technique that uses gentle pressure on specific body areas to trigger automatic movement—to standard physical therapy can improve posture, trunk control, and arm function in people recovering from a first-time stroke. About 62 ad…

This study compares three types of non-invasive brain stimulation combined with hand therapy to see which best helps stroke survivors regain the ability to open their affected hand. About 63 adults who had a stroke 6 to 24 months ago will participate. The goal is to find a more e…

This study tests a wearable suit called Neuro20 that uses mild electrical pulses to stimulate muscles and nerves. Researchers want to see if it can improve walking, muscle strength, and heart rate regulation in 30 adults who have had a spinal cord injury, stroke, or amputation. P…

This study tests whether a precise type of brain stimulation (called high-definition tDCS) can reduce arm stiffness and improve movement in 30 people who have had a stroke. The treatment targets specific brain areas to help rebalance brain signals. The goal is to make it easier f…

This study tests a new speech therapy technique for people with aphasia (trouble speaking) after a stroke. Participants use a mobile app to practice speaking along with an AI-cloned version of their own voice, instead of a therapist's voice. The goal is to see if this personalize…

This study tests whether a special virtual reality (VR) training program can help stroke survivors improve their balance and walking. 38 adults who had a stroke at least 6 months ago will be randomly assigned to either a real VR program with specific visual and balance exercises …

This study tests whether targeted practice in a driving simulator can improve driving skills in veteran stroke survivors. One hundred participants will complete both active training (focusing on speed, lane position, collision avoidance, and dashboard attention) and a control ses…

This study tests a home-based arm exercise program called GRASP for stroke survivors. The program is designed to improve arm movement and prevent disuse of the affected arm. Researchers will enroll 52 adults who have had a stroke and have some arm movement. Participants will do t…

This study tests a non-invasive device called NESA that delivers tiny electrical currents to help people who had a stroke 6 months to 6 years ago. Researchers want to see if it reduces pain, muscle stiffness, and balance problems, and improves sleep, daily activities, and quality…

This study tests a new approach to help people with aphasia (trouble finding words after a stroke) improve their ability to name objects and keep those gains over time. About 30 adults with chronic aphasia will practice naming pictures under timed conditions designed to balance e…

This study explores whether fun activities like dance and video games can help people who have had a stroke improve their balance, movement, and daily function. Researchers will compare these alternative therapies to standard rehabilitation in 120 adults aged 18 to 90. The goal i…

This study tests whether a gentle, non-invasive ultrasound beam aimed at the brain can help people who recently had a stroke regain arm movement. Fifty adults with stroke within the past three months and limited arm strength will receive the treatment. Researchers will check for …

This study tests whether combining mirror therapy with a soft robotic glove helps stroke survivors with arm weakness regain hand function. About 104 adults who had a first stroke and have moderate arm impairment will be randomly assigned to different therapy groups. The goal is t…

This study tests whether a non-invasive brain stimulation technique (TMS) combined with speech therapy can improve language recovery in people who have had a stroke within the past 2 to 6 weeks. About 63 participants will receive either real or fake TMS along with therapy. The go…

This study tests whether a hands-on ankle joint technique can improve how well stroke survivors sense their ankle position. 26 participants who are at least 2 months post-stroke will receive the manipulation, and their ankle awareness will be measured with a special machine. The …

This study tests a new robot that helps people who had a stroke 6 months to 3 years ago improve their walking. The robot encourages patients to move their legs actively rather than just moving them passively. 60 participants will receive 15 training sessions over 5 weeks, and res…

This study tests a program that uses storytelling and skill-building to help young stroke survivors (ages 18-64) return to normal community life. 208 participants will be randomly assigned to the program or usual care. The goal is to improve mobility, social activities, and emoti…

This study tests whether adding musical sounds that match a person's movements (sonification) to standard physical therapy can improve walking in people with Parkinson's disease, stroke, or multiple sclerosis. About 120 adults will be randomly assigned to standard rehab or rehab …

This study tests whether combining prism adaptation training (PAT) with a mild electrical stimulation (TENS) helps stroke survivors who ignore one side of their body. Twenty participants will receive either PAT alone or PAT plus TENS. Researchers will measure improvements in atte…

This study tests if a non-invasive treatment called high-frequency repetitive transcranial magnetic stimulation (rTMS) can improve cognitive problems that happen after a stroke. Researchers will use brain scans to see how the treatment changes brain activity. The trial is recruit…

This study tests whether showing stroke survivors real-time data from wearable ring sensors on their smartphone can encourage them to use their stroke-affected arm more during daily activities. About 50 chronic stroke survivors (more than 12 months since their stroke) aged 18 to …

This study tests a non-invasive brain stimulation technique called iTBS to see if it can improve arm and hand movement in people who had a stroke more than six months ago. Researchers will also look at how the brain changes with this treatment. The study involves 48 adults with l…

This study tests whether a music-based program done at home can help people recover from stroke-related problems with thinking, speaking, moving, and mood. One hundred stroke survivors will either do music activities five times a week for 10 weeks plus usual care, or just receive…

This study tests a new way to help people who have had a stroke move their arm better. It uses a virtual reality system that reads muscle signals and helps guide the arm, combined with gentle brain stimulation to boost learning. The goal is to improve arm function and daily life …

This study tests whether a non-invasive device that gently stimulates a nerve in the ear can improve arm and hand function in people who have had a stroke. Thirty adults with arm weakness from a stroke will receive either real stimulation or a sham (fake) version alongside daily …

This study tests whether a gentle brain stimulation technique called tDCS, combined with computer-based thinking exercises, can improve memory and thinking in people who have had a mild stroke. About 60 adults who had a stroke within the past week will be randomly assigned to rec…

This study tests whether a gentle nerve stimulation device placed on the ear (taVNS) combined with robot-assisted arm training can help people who had a stroke more than 6 months ago regain arm movement. Thirty adults with moderate to severe arm weakness will receive either real …

This study tests whether a gentle electrical stimulation on the tongue, combined with arm training, can improve arm movement and brain rewiring in people who had a stroke at least 6 months ago. 74 participants will receive either real or fake tongue stimulation during a 4-week tr…

This study compares two treatments for leg muscle tightness (spasticity) after a stroke: Botox injections and dry needling. About 90 people who had a first stroke in the past year will be randomly assigned to one session of Botox or 12 weekly dry needling sessions. Researchers wi…

This study tests whether using a virtual reality treadmill (omni-VR) is practical and helpful for people who have had a stroke at least 6 months ago. Thirty participants will either do VR treadmill training or traditional exercise for 45 minutes, three times a week for 12 weeks. …

This study tests whether task-based mirror therapy can reduce pain, swelling, and improve arm movement in stroke survivors who develop shoulder-hand syndrome. About 34 people aged 45-75 will be split into two groups: one gets mirror therapy plus standard care, the other gets stan…

This study tests a robotic glove that reads brain signals to help people who have had a stroke move their hands better. The glove is designed to assist with hand exercises and improve function. The trial will include 60 adults who had a stroke at least 16 weeks ago and have limit…

This study compares two types of exercise—high intensity interval training and intermittent functional training—to see which better improves heart fitness, physical function, and thinking in people who have had a stroke. About 52 adults aged 50-75 who had a stroke at least 6 mont…

This study tests whether a smartphone app powered by artificial intelligence can improve memory, attention, and other thinking skills in people who have had a stroke. Forty adults aged 45-60 with lasting cognitive problems will use the app for training. The goal is to see if thei…

This study tests a wearable device that gives feedback on swallowing muscle activity to help people with swallowing problems from stroke or Parkinson's disease. About 120 adults aged 50-90 will either do swallow therapy in person or at home via telehealth. The goal is to see if t…

This study tests whether a simple, passive robot combined with mild muscle stimulation can help people who have had a stroke regain arm movement. Researchers will enroll 4 adults aged 18–75 who had a stroke and have no major sensation or thinking problems. The goal is to see if t…

This study is testing a device called SynPhNe that stroke survivors can use at home to retrain their hand and arm movement. The goal is to see if it works better than standard care alone. About 40 people who had a stroke at least 6 months ago and have moderate hand weakness will …

This study tests whether adding music training and group leisure activities to standard hospital rehab helps people recover better after a stroke. About 90 adults who recently had a stroke will be split into three groups: standard rehab alone, standard rehab plus individual music…

This study tests whether adding a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to standard rehabilitation can improve heart rate variability (a sign of healthy heart control) in 44 stroke survivors. Participants will receive …

This study is testing whether two non-invasive brain stimulation techniques can improve arm function in people who have had a stroke. The techniques involve stimulating the arm muscles and the tongue with mild electrical pulses. The goal is to see if these methods help stroke sur…

This study compares two walking training methods for people who have had a stroke: one uses a body-weight support system with forward and backward walking, and the other uses virtual reality games during walking. The goal is to see which method better improves walking speed, bala…

This study tests whether applying kinesio tape (a stretchy, therapeutic tape) to the neck muscles can improve swallowing safety in people who have trouble swallowing after a stroke. Researchers will measure changes using video X-rays before and right after taping. The study enrol…

This study tests a wearable hand orthosis called MyHand 2 for stroke survivors who have weakness on one side. The goal is to improve hand function and daily activities. Researchers will refine the device based on feedback from 60 adult participants who had a stroke at least six m…

This study tests a special mouth exercise program using a device to help people who still have trouble swallowing 12 weeks after a stroke. About 60 participants will be randomly assigned to the program or standard care. The goal is to see if the exercises improve swallowing funct…

This study tests a 10-week power training program for people who had a stroke at least 6 months ago. The goal is to see if fast, explosive exercises can improve walking, strength, and balance better than standard slow strength training. Sixty participants will be randomly assigne…

This study tests a 12-week dance and movement program for stroke survivors who have weakness on one side of the body. The goal is to see if it helps them take part in daily and social activities more easily, and improves balance, walking, confidence, and quality of life. About 16…

This study is testing a new, non-invasive brain stimulation technique called 'mirror-PAS' to help people who have had a stroke or suffer from phantom limb pain. The goal is to see if this method can improve movement in stroke patients and reduce pain in those with phantom limb pa…

This study tests a new system that combines virtual reality with a walking robot to help people who have had a stroke walk with a more natural, balanced stride. The robot gives real-time feedback to encourage using the weaker leg more. Researchers will compare 15 stroke survivors…

This study tests whether using mild brain stimulation before walking therapy can help people who have had a stroke walk better. About 100 adults who had a stroke at least 3 months ago and still have trouble walking will take part. The goal is to see if this approach improves walk…

This small pilot study tests whether a home-based cognitive strategy program (PRPP-I) can help adults with chronic stroke become more independent in daily activities like dressing, cooking, and bathing. Researchers will enroll 18 participants to see if the program is feasible and…

This study looks at whether doing aerobic exercise (like walking or cycling) right before physical therapy can help stroke survivors recover better. The goal is to improve arm movement, thinking skills, and mood. About 40 Veterans who had a stroke at least 6 months ago will take …

This early-stage study at Johns Hopkins University is testing whether psilocybin, a psychedelic compound, is safe for people who had a stroke at least one year ago. The study will enroll 20 adults and closely monitor their blood pressure and any psychiatric changes. The goal is t…

This study compares two exercise programs—trunk training and lateral tilt balance training—to see which better helps stroke patients improve trunk control, balance, and daily activities. It involves 44 adults aged 40-75 who had a stroke 6 months to 1.5 years ago and can walk 10 m…

This study tests a wearable device that sends gentle, low-frequency electromagnetic fields to the brain to help people who had a stroke more than 6 months ago recover arm movement and reduce disability. About 25 adults with chronic stroke will use the device in a clinic setting. …

This study tests whether combining synergy-based motor therapy with neuromuscular electrical stimulation can improve arm and hand function in people who had a stroke 3 to 6 months ago. About 40 adults aged 50 to 65 with mild to moderate arm weakness will participate. The goal is …

This study looks at two different ways to help people who have had a stroke improve the use of their affected arm and hand. One method uses exercises with just the affected arm, while the other uses both arms together. Thirty-two adults who had a stroke 6 to 24 months ago will ta…

This study tests a non-invasive treatment that sends mild electrical pulses to the spinal cord to improve walking and balance in people who have weakness on one side of the body due to a stroke. Researchers will enroll 115 adults who are at least 6 months past their stroke and ca…

This study tests a new virtual reality system that combines mirror therapy with fun games to help stroke patients improve arm movement. Researchers will check how comfortable and easy the system is to use in 172 healthy volunteers and stroke survivors. The goal is to see if this …

This study tests whether special balance (vestibular) exercises can help reduce fatigue in people who have had a stroke. Thirty adults who had a stroke at least 6 months ago will either do these exercises or standard rehab three times a week for one hour. Researchers will measure…

This study tests whether adding a vibrating sensation to the arm can help stroke survivors who have lost some sense of where their arm is. Thirty people who had a stroke at least six months ago will try reaching for objects and drinking from a glass while wearing a device that bu…

This study looks at how different amounts and types of walking therapy affect people who had a stroke 1 to 6 months ago. Researchers want to see if more intense or more task-specific walking practice helps improve how far people can walk, how often they walk in daily life, and th…

This study tests a digital mirror therapy using augmented reality to help people who had a stroke more than 6 months ago improve arm movement. 44 participants will get either digital or standard mirror therapy for 10 sessions over 3 weeks. The goal is to see if the digital versio…

This study tests a new type of therapy for people who have had a stroke and have trouble moving their arm or hand. It uses a virtual reality system that lets patients see a 3D reflection of their good arm moving, which may help rewire the brain. Researchers will compare this VR a…

This study tests whether using a special visual device that creates the illusion of movement can help people who had a stroke regain better use of their arm and hand. About 66 participants, 4 to 10 weeks after their stroke, will either get standard therapy or add sessions with th…

This study tests whether a digital program called Sleepio, which uses cognitive behavioral therapy for insomnia, can improve sleep in stroke survivors. Researchers will also see if better sleep helps with learning motor skills during rehabilitation. About 100 adults who have had …

This study tests whether adding a home-based telerehabilitation program to usual care helps people with arm weakness after a stroke. About 202 participants who had a stroke 90-150 days ago will be randomly assigned to either receive telerehabilitation plus usual care or usual car…

This study tests whether special knee strengthening exercises can improve balance and body awareness (proprioception) in people who had a stroke. About 34 adults, 3 months to 1 year after their stroke, will do these exercises on a machine. The goal is to see if this helps them mo…

This study compares robot-assisted training to standard physical therapy for people who had a stroke 6-24 months ago and still have moderate to severe movement problems. The goal is to see if robot training improves leg function, daily activities, fatigue, and quality of life. Fo…

This study tests whether adding neuromuscular electrical stimulation (NMES) to standard facial exercises helps people who have facial weakness after a first-time stroke. Researchers will measure changes in facial symmetry using video recordings. The trial aims to recruit 130 adul…

This study tests whether forced aerobic exercise (using a stationary bike that helps move your legs) can improve arm and leg recovery in people who had a stroke 3-9 months ago. Researchers will measure movement, brain activity, and blood markers of healing, and compare costs to s…

This study tests whether a gentle brain stimulation technique (rTMS) can make walking and thinking training more effective for people who had a stroke at least 6 months ago. About 184 adults aged 50+ will get either real or fake stimulation before each training session, 12 times …

This study is testing if a new type of physical therapy using robotic arms and video game-like exercises can help improve both thinking skills and arm movement in adults with Parkinson's disease, multiple sclerosis, or who have had a stroke. Researchers want to see if this high-t…

This study aims to learn how the brain and spinal cord change after a stroke. Researchers will use MRI scans to compare stroke patients with healthy volunteers. The goal is to find patterns that predict recovery and understand why symptoms vary. About 35 people will take part.

This study looks at how the brain changes after a stroke and how those changes affect arm and hand movement. Researchers will use brain scans and movement tests to find early signs that predict recovery. The goal is to better understand why some people develop movement problems a…

This study looks at how stroke changes the way people move their arms when walking. Researchers will measure brain activity and muscle patterns in 84 people (stroke survivors and healthy volunteers) to understand why arm swing is different after a stroke. The goal is to use these…

This study is looking for DNA markers that might predict the risk of silent strokes in older adults having a minimally invasive heart valve replacement called TAVR. Researchers will measure DNA methylation in blood samples before and after the procedure and compare it to brain sc…

This study looks at a blood marker called BD-tau, which may show how much brain injury happens after a stroke. Researchers will take blood samples every hour for 48 hours from 100 adults who had a stroke. The goal is to learn when the marker rises and how long it stays high, whic…

This study looks at how changes in brain blood flow affect breathing control during sleep in healthy adults. Researchers will use mild oxygen changes and a placebo to measure responses. The goal is to better understand conditions like sleep apnea, not to treat them directly.

This study is looking at whether people with psoriasis have a higher risk of heart disease. Researchers will follow 1,000 adults with psoriasis, using heart scans and blood tests to find early warning signs. The goal is to better understand the link between psoriasis and heart pr…

This study follows 130 patients with severe brain injuries (from stroke, trauma, or lack of oxygen) who are in a coma or minimally conscious state. Researchers will use brain scans, electrical tests, and regular check-ups to find clues that predict if and when a patient might reg…

This study is building a large registry of people who have had a stroke and still have symptoms. The goal is to connect them with researchers working on new ways to improve recovery. No treatment is given; participation simply involves joining the registry.

This study looks at whether people who have a pulmonary embolism (a blood clot in the lungs) are more likely to have a stroke if they also have a small hole in their heart, called a PFO. About 1 in 4 people have this hole, which can let a clot travel from the veins to the brain. …

This study compares a new, data-driven stroke transport plan to the current method for getting stroke patients to the right hospital. The goal is to see if the new plan helps rural patients get life-saving treatment faster. About 360 adults with suspected stroke will take part, a…

This study looks at how a non-invasive brain stimulation technique called cortical priming affects the ability to learn leg movements in both healthy adults and people who had a stroke at least six months ago. Researchers will measure improvements in stepping speed and brain acti…

This study looks at 100 people who had a stroke with no clear cause. They will get a heart MRI to measure scar tissue in the left atrium, which might lead to atrial fibrillation. The goal is to see if the MRI can predict who will develop atrial fibrillation, so doctors can better…

This study looks at how to make stroke rehabilitation research more inclusive, especially for women and people with aphasia (trouble speaking or understanding language). Researchers will test a new way of recruiting participants and compare it to the usual method. The goal is to …

This study tests a non-invasive device that gently stimulates a nerve in the ear (taVNS) in people who had a stroke within the past month and have arm weakness. Researchers will measure brain activity with EEG and look at certain genes to see if taVNS helps recovery. The goal is …

This study aims to find out if a simple ECG test can identify which patients with atrial fibrillation are at risk of forming blood clots that lead to stroke. Researchers will analyze heart tissue and blood samples from 1,000 adults undergoing open-heart surgery, along with their …

This study aims to understand why many people feel extremely tired after a stroke, a condition called post-stroke fatigue. Researchers will monitor 250 stroke patients' heart rate, blood pressure, and heart function to see if problems with the body's automatic nervous system are …

This study tests a new way to help people who have had a stroke walk more symmetrically. Researchers will use a split-belt treadmill (where each leg moves at a different speed) along with resistance and real-time feedback (like sounds or visuals) to encourage stronger pushes from…

This study is testing a special glove with sensors to see how well it can measure touch and thinking problems in people who have had a stroke. About 126 adults who had a stroke within the last six months will try the glove. The goal is to make the glove better and to create a new…

This study looks at how placebos (inactive treatments) affect the brains of people recovering from stroke. Researchers will give placebos openly or secretly to 56 adults with chronic stroke and measure brain activity with EEG. The goal is to understand how placebos work in the br…

This study aims to understand how the brain responds to magnetic stimulation when it is timed with natural brain oscillations. Researchers will test healthy adults and people who had a stroke at least 6 months ago. The goal is to find ways to make brain stimulation more effective…

This study looks at why people who have had a stroke often have trouble coordinating their legs when walking. Researchers will measure brain and nerve signals in 50 adults with chronic stroke to find out what causes these coordination problems. The goal is to gather knowledge tha…

This study looks at how muscles work together after a stroke and whether a special exercise program guided by muscle signals can improve arm movement. Researchers will test 74 people, including stroke survivors and healthy adults, to see if retraining muscle coordination reduces …

This study tests whether a smartphone app called ICanWALK can teach people to use walking aids like crutches, canes, and walkers more safely. Researchers will enroll 52 adults who use a walking aid most of the time due to a leg injury, stroke, or multiple sclerosis. The goal is t…

This study looks at why some people with muscle, bone, or joint problems follow their home exercise programs while others don't. Researchers will track 252 adults with conditions like back pain, arthritis, or stroke recovery. They want to find out what personal, social, and healt…

This study is a large international registry that collects information from up to 40,000 people who have had surgery for stroke, brain aneurysm, or other blood vessel problems in the brain. The goal is to track complications, success rates, and retreatment needs to help doctors b…

This study is testing whether the EXOPULSE Mollii Suit can improve balance and reduce fall risk in people with cerebral palsy, multiple sclerosis, stroke, or fibromyalgia. Researchers will track changes in balance scores and walking speed over time. The goal is to identify which …

This study tests whether personalized transcranial direct current stimulation (tDCS) can help people with chronic stroke regain arm function. Researchers will use brain scans to see if the stimulation improves connections in the brain. The study involves 80 adults who had a strok…

This study tests new guidelines for placing sticky electrodes on the calf muscles of people who have had a stroke. The goal is to get more accurate readings of muscle activity during walking and exercises. Twenty participants will have electrodes placed using both the new and old…

This study looks at how people who had a stroke more than 6 months ago learn a new way of walking using distorted visual feedback. Researchers want to see if a short bout of exercise right after learning helps them remember the new walking pattern a day later. About 80 participan…

This study looks at how deep brain stimulation (DBS) changes movement in people with conditions like Parkinson's disease or essential tremor. About 60 people already scheduled for DBS surgery will have temporary brain recordings during their procedure. The goal is to understand t…

This study looks at how stroke changes the way the spinal cord handles sensory information. Researchers will stimulate nerve roots in the neck during surgery and measure muscle and brain responses in 15 people (some with stroke, some without). The goal is to better understand spi…

This study aims to understand how the brain changes when people recover arm movement after a stroke. Researchers will enroll 50 people who had a stroke 3-6 months ago and have moderate to severe arm weakness. Participants will either receive intensive arm training or usual care, …

This study is testing a new, non-invasive wearable patch with a microphone that listens to swallowing sounds in people who have trouble swallowing after a stroke. Researchers will collect these sounds during a standard swallowing X-ray test and use machine learning to find patter…

This study tests a new ultrasound technology called NeoDoppler that can continuously monitor blood flow in the brains of sick and premature infants. Researchers will enroll 180 newborns, including healthy preterm and term babies as well as those with conditions like heart defects…

This study monitors how much stroke survivors move their affected arm during everyday activities. Researchers will track hand movements, joint range, and wrist distance using wearable sensors. The goal is to link real-world movement data with standard recovery tests. 40 adults wh…

This study looks at whether certain gene changes (variants of the ANXA2 gene) make some people more likely to have a stroke, especially when the cause is unknown. Researchers will compare blood samples from 240 adults who have had a stroke with no clear cause. The goal is to find…

This study compares a new MRI-based method (IMPROVE) against the standard approach for deciding which patients with narrowed carotid arteries need surgery or stenting. The standard method mainly looks at how narrow the artery is, while IMPROVE checks for unstable plaque that rais…

This study follows 400 stroke patients in rehabilitation units to see how their walking and balance improve over six months. No new treatments are tested—researchers simply measure progress using standard walking and balance tests. The goal is to better understand recovery patter…

This study is testing a detailed health assessment process called 'deep phenotyping' in up to 100 young adults aged 18 to 55 who have had a stroke. Researchers will collect a wide range of information and samples to better understand each person's condition and recovery. The goal…

This study is creating a large collection of blood samples from 1,000 people with atrial fibrillation (an irregular heartbeat) and stroke. Researchers will analyze the DNA and plasma to better understand the genetic causes linking these conditions. The goal is to find new targets…

This study tests an 8-week online program designed to help working-age stroke survivors start their own business. Researchers want to see if the program increases self-employment rates, confidence, and life satisfaction. About 156 participants who have been out of paid work for a…

This study is looking for brain signals (biomarkers) that can help doctors track and predict how well stroke patients recover their ability to walk. About 30 adults who have had a stroke and can walk with some help will use a robotic device while their brain activity is measured.…

This study compares two rehabilitation approaches to improve finger movement in 40 people who had a stroke 6 months to 2 years ago. One method encourages using any strategy to reach goals, while the other focuses on improving movement technique. Participants will do 10 days of pi…

This study is testing whether wearable body sensors can accurately monitor and predict recovery in people recovering from a stroke during inpatient rehabilitation. Researchers will collect data from 400 participants, including stroke patients and healthy volunteers, to see if mac…

This study looks at how a gentle electrical current applied to the scalp can change brain activity in people who had a stroke over 6 months ago. Researchers will test two different stimulation frequencies and a placebo in 45 participants, including healthy volunteers. Using brain…

This study follows 24 adults who had a stroke and were recently diagnosed with atrial fibrillation (AF), a heart rhythm problem. Researchers will track how AF changes over two years using heart monitors and blood tests. The goal is to better understand AF progression in stroke su…

This study looks at how the brain talks to muscles in people who have had a stroke. Researchers will use gentle brain stimulation and measure brain and muscle activity while participants squeeze a device with their weak hand. The goal is to see if stimulation improves communicati…

This study will follow 5,000 people who are getting a new type of device to treat a brain aneurysm. The goal is to see how safe and effective these devices are, and to find out what factors might make an aneurysm come back after treatment. Researchers will look at things like smo…

This study looks at whether a training program that mixes mental tasks with physical exercises can improve thinking and movement in people who have had a stroke or have Moyamoya disease. Researchers will measure brain activity during these tasks using a special headband. The goal…

This study reviews medical records from 100 adults who had a stroke and were treated at hospitals in Villavicencio, Colombia. Researchers want to see how quickly and effectively stroke care is given, and whether it follows best-practice guidelines. The goal is to find ways to imp…

This study tests whether a camera-based system can track arm movements and posture during robot-assisted therapy for stroke survivors. The goal is to see if group therapy sessions (up to 3 people) work as well as individual sessions. About 42 adults who had a stroke 6 months to 6…

This study looks at whether a fast genetic test can help doctors choose the best blood-thinning medicine for people who have had a minor stroke or a high-risk transient ischemic attack (TIA). About 200 adults admitted to the hospital will provide a cheek swab for DNA testing. The…

This study will follow about 10,000 adults in China who receive the clot-dissolving drug tenecteplase for a stroke. Researchers want to see how well patients recover and if there are any safety issues in real hospital settings, not just controlled trials. The goal is to improve s…

This study is testing a noninvasive technique that uses mild electrical pulses on the skin over the spine to see if it can improve arm and hand function in people who have had a stroke or spinal cord injury. Researchers will measure changes in nerve activity and movement in 30 ad…

This study explores whether a brain imaging technique called fMRI neurofeedback, combined with imagining hand movements, can help stroke survivors improve their reading. About 28 people who had a stroke in the left side of their brain and now have reading problems will practice c…

This study checks if a pressure-sensitive insole (Ceriter Stride One) can accurately measure walking patterns in people recovering from stroke, brain injury, or spinal cord injury. About 30 participants will wear the insoles while walking on a high-tech treadmill (GRAIL) before a…

This study looks at a small leg muscle called the plantaris and its role in treating tight ankles (ankle equinus) in children aged 4-17. About 42 kids having surgery for this condition will have the plantaris and larger calf muscles lengthened in a random order. The goal is to se…

This study explores whether combining non-invasive brain and spinal cord stimulation during a thinking-and-moving task can improve sensation, movement, and thinking in people who have had a stroke or cervical spinal cord injury. About 45 participants (including healthy volunteers…

This study looks at how small vessel disease in the brain affects thinking skills. Researchers will use EEG to measure brain activity in 80 older adults and test if personalized brain training or gentle electrical stimulation can help. The goal is to find better ways to detect an…

This study is testing whether a non-invasive ultrasound scan, combined with artificial intelligence, can quickly identify bleeding in the brain (intracerebral hemorrhage) in people having a stroke. About 500 adults with stroke symptoms will get an ultrasound within 48 hours, and …

This study looks at whether thinking about a target outside your body (external focus) or thinking about your own movements (internal focus) helps people who have had a stroke stand up from a chair more evenly. Twenty adults who had a stroke at least six months ago will practice …

This study looks at whether combining prism adaptation training with electrical stimulation can help people who have had a stroke and have spatial neglect (trouble noticing things on one side). Researchers will measure changes in pointing, brain activity, and walking. The study i…

This study looks at whether a new clinical test called the Ad-AHA Stroke accurately measures how stroke survivors use both hands together in daily life. Researchers will compare test scores with real-world data from wrist-worn sensors worn for three days at home. The goal is to s…

This study looks at how things like education, race, and income might affect a person's memory and thinking after a stroke. Researchers will talk with 450 adults who had a stroke and review their brain scans. The goal is to understand why some people recover better than others.

This study tests if combining a gentle brain stimulation technique (tDCS) with watching hand movement videos (action observation therapy) can help people who had a stroke regain hand function. 60 adults with chronic stroke will receive 10 sessions of either the combined therapy, …

This study looks at how using arm support (like a cane or walker) changes the way people who have had a stroke walk. About 34 adults who had a stroke will walk on a special treadmill with no support, one-arm support, and two-arm support. The goal is to learn which support method …

This study tests if a wearable headband that uses sound waves and light can safely monitor blood flow in the brains of people who have had a stroke, as well as those with dementia, depression, or delirium. Researchers will also use artificial intelligence to analyze the data. Abo…

This study is testing how much walking practice on a special treadmill (split-belt treadmill with virtual reality) people who recently had a stroke can handle in one day. The goal is to find the right amount of training that is safe and tolerable. 72 stroke survivors who had thei…

This study tests whether a live video call between a neurologist and ambulance paramedics can improve the detection of strokes before reaching the hospital. About 512 adults with suspected stroke will take part. The goal is to see if video assistance helps paramedics use stroke s…

This study looks at sleep problems like sleep apnea and insomnia in people who have had a stroke. Researchers want to see how these sleep issues affect recovery, daily activities, and quality of life. About 226 stroke survivors will use home sleep tests and wearables to track the…

This study is testing whether a new digital test battery called Mindmore Distance can accurately assess thinking and memory skills in people with neurological conditions like traumatic brain injury, stroke, multiple sclerosis, Parkinson's disease, epilepsy, or brain tumors. Resea…

This study looks at whether a modified cardiac rehabilitation program can improve physical and emotional recovery in people who have had a stroke. Researchers will enroll 76 adults aged 18-80 who had a stroke at least 6 months ago and have some leg weakness. The goal is to see if…

This study tests whether temporarily stimulating a specific part of the brain can improve hand, arm, and speech abilities in people who had a stroke at least 6 months ago. Ten participants will have a thin wire placed in the brain for less than 30 days to deliver mild electrical …

This study looks at how changing visual feedback in a virtual reality environment affects hand muscle coordination in 15 chronic stroke survivors and 15 healthy adults. Participants perform finger movements while their joint angles are either amplified or reduced on screen. The g…

This study tests whether gentle muscle vibrations can help the brain form new connections after a stroke or traumatic brain injury. Researchers will measure brain and nerve activity in 56 participants before, during, and after a 5-week vibration treatment. The goal is to understa…

This study explores whether a brain-computer interface (BCI) can help people with motor disorders, like spinal cord injury or stroke, control assistive devices just by thinking about moving. Researchers will use electrical stimulation to train the brain and improve BCI accuracy. …

This study watches and analyzes video recordings of occupational therapy sessions for adults recovering from stroke or spinal cord injury. Researchers want to identify exactly what therapists do to help improve arm and hand function. The goal is to create a toolkit that makes reh…

This study explores whether high-density brain surface recordings can decode imagined Mandarin Chinese speech, including tones, without any actual speaking. About 50 adults with brain conditions like epilepsy or tumors, plus 10 with severe speech loss from stroke or ALS, will hav…

This study looks at how the diaphragm (the main breathing muscle) changes after a stroke that causes weakness on one side of the body. Researchers will measure diaphragm movement and thickness using ultrasound and compare it to breathing strength in 38 adults who had a stroke 1 t…

This early study tests whether a brain implant can help people with severe paralysis from conditions like ALS, spinal cord injury, or stroke control devices using their thoughts. The implant records brain signals to decode intended movements or speech, aiming to restore communica…

This study is tracking 350 stroke patients in the Asia-Pacific region to see how well a procedure called endovascular thrombectomy (clot removal) works outside of clinical trials. Researchers want to understand what helps or hinders recovery in everyday hospital settings. The goa…

This pilot study is testing whether a non-invasive eye scan called OCTA can detect changes in blood flow in people with neurological conditions like stroke and brain hemorrhage. Researchers will compare scans from 50 patients and healthy volunteers to gather preliminary data. The…

This study looks at 500 people who have had a stroke and also have atrial fibrillation (an irregular heartbeat). The goal is to understand why some people still have strokes even when taking blood thinners. Researchers will collect blood samples and heart ultrasound images to fin…

This study looks at whether low magnesium in the blood is linked to thinking problems after a stroke. Researchers will measure magnesium levels and test memory, orientation, and other cognitive skills in 80 stroke patients over several weeks. The goal is to understand if magnesiu…

This study tests whether a computer model can predict which reading therapy works best for people who developed dyslexia after a stroke. Twelve participants will receive two different types of intensive reading therapy, and researchers will compare the results to the model's pred…

This study follows 150 people who recently had a stroke to understand how walking ability returns over time. Researchers will measure walking speed and distance, and test if specific therapies can improve recovery. The goal is to create better rules for predicting and enhancing r…

This early study tests a smartphone app that creates a 'digital twin' of the patient to help manage health after a stroke. 20 adults who have had a stroke, or have moyamoya disease or cerebral amyloid angiopathy, will use the app daily for six months alongside standard care. The …

This study looks at how fear of movement (kinesiophobia), balance, and fear of falling are connected in people recovering from a stroke. About 138 stroke patients will fill out surveys and do balance tests. No new treatment is given; the goal is to better understand these factors…

This study explores how brain stimulation can help people who have had a stroke move faster. Researchers will first test healthy volunteers to map brain areas controlling reaction time, then apply targeted stimulation to stroke patients. The goal is to understand the brain circui…

This study is testing a new device that measures pressure around the brain from outside the head, avoiding the need for risky surgery. Researchers will collect data from 581 patients who already have standard surgical monitors, to help develop a safer, non-invasive alternative. T…

This study measures how touch signals move from the finger through the nerves to the brain. Researchers will test 60 people, including young adults and stroke survivors, to see how stroke changes touch perception. Participants will feel different force levels on their finger whil…

This study uses special high-resolution and high-speed cameras to take detailed pictures of the eye. The goal is to see tiny structures that regular eye exams miss, which could help doctors better understand eye diseases. About 1,200 people with various eye conditions or healthy …

This study looks at how often fatigue happens after a person's first stroke and what factors—like pain, mood, or sleep—make it worse. Researchers will follow 107 adults who had a stroke at least three months ago. The goal is to better understand post-stroke fatigue so doctors can…

This study follows 213 adults recovering from a first ischemic stroke to see if the intensity of rehabilitation (3-5 sessions per day vs. 1 session per day) affects their functional recovery at six months. It also compares outcomes between patients whose stroke was linked to atri…

This study looks at how quickly people with stroke or memory problems can move. Researchers want to see if new short tests can help predict recovery after a stroke or help diagnose diseases like Alzheimer's earlier. About 129 adults aged 40 to 85 will take these quick tests, and …

This study tests whether a virtual reality walking program can be used as part of regular therapy for people recovering from a stroke. About 40 participants will do personalized VR training twice a week for four weeks. The goal is to see if the program is practical and well-liked…

This study looks at how to better measure and treat a condition called neglect, where stroke survivors ignore one side of their world. Researchers will test a treatment that combines repetitive task practice with a gentle brain stimulation technique. The goal is to see if this ap…

This study looks at how a single session of exercise can temporarily reduce sensitivity to pain in both healthy adults and stroke survivors who do not currently have pain. Researchers will measure pain thresholds before and after exercise to understand the body's natural pain-blo…

This small pilot study looks at how Botox injections change the muscles, tendons, and nerves in the feet of people who had a stroke and developed a stiff, twisted foot. Researchers will use special ultrasound and movement tests to measure these changes in 12 first-time stroke pat…

This study explores whether a personalized form of brain stimulation (TMS) can better activate the brain pathways that control hand movement after a stroke. Researchers will compare this tailored approach to standard TMS in 37 adults who had a stroke at least 6 months ago and sti…

This study follows 5,000 adults in Hong Kong who either have or are at high risk for brain diseases like stroke and dementia. Researchers will collect medical records, surveys, and phone interviews over many years to identify what factors lead to these conditions. The goal is to …

This study looks at the thickness of a specific layer of back tissue (thoracolumbar fascia) in people who had a stroke at least 6 months ago. Researchers want to see if this thickness is related to balance, trunk control, flexibility, and daily independence. 70 participants will …

This study looks at whether giving a clot-busting drug to stroke patients 4.5 to 24 hours after symptoms start can help them recover better. Researchers will review medical records from 2,600 adults to see how many achieve good function or minimal disability. The goal is to find …

This study is testing a new system that uses brain scans to time magnetic pulses precisely, aiming to improve arm movement in stroke survivors. Researchers will first test the system in healthy adults, then in 100 people who had a stroke at least 6 months ago. The goal is to see …

This study looks at why walking is harder for people who have had a stroke. Researchers will test a new method to measure walking efficiency using motion and force, comparing it to standard energy-use tests. 18 adults with chronic stroke who walk slowly will do three short treadm…

This study uses MRI scans to look at brain and spinal cord activity in people who have had a stroke and have weakness on one side. Researchers want to understand which nerve pathways the brain uses to move the shoulder. The goal is to learn more about how movement is controlled a…

This study is testing whether brain scans and a technique called transcranial magnetic stimulation can predict how well someone will recover arm movement after a stroke. Researchers will collect data from 657 adults who recently had a stroke and have arm weakness. The goal is to …

This study looks at how swelling around a brain bleed affects recovery. Researchers will follow 500 adults who had a spontaneous hemorrhagic stroke to see if the swelling is linked to long-term disability. The goal is to better understand this swelling so future treatments can ta…

This study enrolls 500 people with brain small vessel disease (CSVD) to see how genetics influence their condition. Participants get genetic testing for five key genes and are followed for at least two years. The goal is to track strokes and dementia, not to test a new treatment.

This study is collecting movement, daily activity, and genetic data from 70 stroke patients to create a 'digital twin' — a computer model that mirrors each patient. The goal is to better predict how someone will recover after a stroke. No new treatments are being tested; this is …

This study checks if a hand laterality task (judging whether a pictured hand is left or right) is a valid tool for stroke patients. About 30 adults who have had a stroke will complete reaction time and hand judgment tasks. The goal is to see how well this test measures thinking a…

This study looks at why stroke survivors' leg muscles get tired faster than normal. Researchers will measure blood flow to the leg during exercise and test a safe, non-invasive technique called ischemic conditioning to see if it can improve blood flow and reduce muscle fatigue. T…

This study uses powerful MRI scanners to create a detailed map of how the brain reorganizes after a stroke. Researchers will scan 100 stroke patients and 10 healthy volunteers to understand how brain connections relate to movement problems. The goal is to improve rehabilitation a…

This study is testing a new questionnaire called the Pressure Relief Frequency Scale (PReFS) to see if it can help wheelchair users with neurologic disorders (like spinal cord injury, stroke, or traumatic brain injury) know how often they should shift their weight to prevent pres…

This study explores whether backward walking training can improve gait and balance in Veterans who have had a stroke. Researchers will compare two different training schedules (18 vs. 27 sessions) and use brain scans to understand how the brain changes with therapy. The goal is t…

This study aims to find biological markers that can predict which stroke survivors will improve their walking speed with high-intensity interval training (HIIT). Researchers will measure blood lactate levels and brain activity in 55 Veterans with chronic stroke to build a model t…

This study tests a non-invasive wrist monitor that continuously checks for stroke by detecting arm weakness. It aims to catch strokes faster in 1,200 high-risk hospital patients, while keeping false alarms low. The goal is to improve treatment and outcomes without any drugs or su…

This study aims to understand if COVID-19 vaccines have any impact on brain health. Researchers will use MRI scans to look at the brains of 500 healthy adults in Hong Kong, comparing scans taken before and after vaccination. The goal is to provide clear, evidence-based informatio…

This study looks at how genes and brain scans can help predict recovery from aphasia, a language disorder that often follows a stroke. Researchers will study 90 adults aged 40-90 who have had a stroke, using MRI and genetic tests to understand why some people recover better than …

This study looks at how memory and thinking problems after a stroke affect a person's ability to relearn walking. Researchers will use walking tests, brain scans, and thinking assessments in 65 older adults who had a stroke at least 6 months ago. The goal is to find better ways t…

This study tests a wearable device called Neuralert that monitors hospital patients at high risk for stroke. The device is worn on both arms and sends alerts if it detects signs of a stroke. The goal is to see if it can identify strokes faster than current methods. About 50 adult…

This study will collect information from HeartMate 3 heart pumps in 150 adults to see if pump data can predict problems like bleeding, infection, or frailty. Researchers want to understand how pump readings relate to patients' quality of life and health outcomes. The goal is to h…

This study follows 140 working-age stroke survivors in France to understand what factors help or hinder their return to work. Researchers will look at medical details, personal beliefs, and job-related issues. The goal is to create better support plans for people recovering from …

This study aims to better understand the role of blood clots in different types of stroke. Researchers will use a special PET scan tracer that sticks to activated platelets, the cells that form clots, to see where clots are in the body. The study will involve 120 adults who have …

This early study tests whether a robot can help doctors perform delicate brain blood vessel procedures, such as taking images, blocking blood flow to tumors, or removing clots during a stroke. Ten people already scheduled for these standard treatments may have their procedure don…

This study looks at how the brains of 25 stroke patients with weak hand muscles work when they do mirror movements. Researchers use a special brain scanner to measure activity. The goal is to learn more, not to test a treatment.

This study looks at how shoulder pain on the paralyzed side affects arm function, balance, fear of falling, and independence in people who have had a stroke. Researchers will measure these factors in 62 adults with stroke and shoulder pain. The goal is to better understand the re…

This observational study looks at whether the settings on a breathing machine (like pressure and power) are linked to how severe a person's brain injury is. It includes 19 adults with brain injuries from stroke, trauma, or bleeding who need a breathing machine. The goal is to see…

This study looks at how taking multiple medications affects the health of elderly people with chronic diseases like heart disease, diabetes, and high blood pressure. Researchers will survey 2000 patients aged 65 and older in Shaanxi Province, China, over two years. The goal is to…

This study aims to understand how two mental practice techniques—imagining movements and watching others perform movements—affect muscle activity in stroke survivors. Researchers will measure electrical signals in arm and hand muscles of 28 participants during these exercises to …