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Can piano training rewire the brain after a stroke?

NCT ID NCT06604143

Knowledge-focused Sponsor: University of Toronto Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two rehabilitation methods to improve finger movement in 40 people who had a stroke. One method encourages using any strategy to reach goals, while the other focuses on improving movement technique. Participants will do 10 days of piano training and have brain scans to see how the brain adapts, helping researchers understand which approach works best for different people.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Over 18 years of age * Diagnosis of first time unilateral ischemic or hemorrhagic * Stroke occurrence: \> 6 months and \< 2 years * Able to perform active finger movements (Chedoke-McMaster (CM) Impairment Inventory of the Hand, Stage ≥ 3) Exclusion Criteria: * History of developmental, neurological, or major psychiatric disorders * Cognitive deficits (\< 23/30 Montreal Cognitive Assessment) * Apraxia (\<2SD mean Waterloo Apraxia test) * Neglect (\> 40/100, Sunnybrook Neglect Assessment Procedure) * Cerebellar stroke * Musculoskeletal injury affecting motor performance * Inability to sit in a chair and perform exercises for sustained periods * Contraindications to MRI

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Conditions

The condition(s) this trial relates to.

stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    5 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Jewish General Hopsital

    RECRUITING

    Montreal, Quebec, H7V 1R2, Canada

  • Jewish Rehabilitation Hospital

    RECRUITING

    Laval, Quebec, H7V 1R2, Canada

  • Lethbridge-Layton-Mackay Rehabilitation Center

    RECRUITING

    Montreal, Quebec, H4B 1T3, Canada

  • University Institute for Physical Impairment Rehabilitation of Montreal (IURDPM)

    RECRUITING

    Montreal, Quebec, H3S 2J4, Canada

  • University of Toronto

    RECRUITING

    Toronto, Ontario, M5S 2W6, Canada

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