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HIIT workouts tested as a way to fight Post-Stroke fatigue

NCT ID NCT07273058

Symptom relief Sponsor: The Hong Kong Polytechnic University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether high-intensity interval training (HIIT) can reduce fatigue in people who have had a stroke. Sixty chronic stroke survivors with fatigue will be randomly assigned to HIIT, moderate exercise, or stretching for 12 weeks. The main goal is to see if the program is practical and acceptable, while also measuring changes in fatigue and inflammation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
High-intensity interval training (HIIT)
What this could lead to
If it works, this could point toward an exercise program that helps reduce fatigue in people who have had a stroke.
What could go wrong
This is a small, early pilot study with only 60 participants, so results may not apply to everyone. The main goal is to see if the program is feasible, not to prove it works.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * Age of 40-80 years; * a history of ischemic stroke resulting in unilateral limb impairment 6-60 months prior to consent to participate in the pilot trial; * a stable medical condition; * a subjective feeling of fatigue, defined as a period of apparent fatigue, decreased energy, increased need for rest, or fatigue out of proportion to physical activity for at least 2 weeks during the past month; * ability to communicate with the investigators and lack of significant cognitive deficits; * able to walk for 10 meters with or without a walking aid. Exclusion criteria: * An FSS score of \< 4 (20); * other neurological conditions; * other musculoskeletal comorbidities that would prevent safe participation in exercises; * a medical diagnosis of significant cardiovascular, pulmonary, or metabolic disease(s); * signs or symptoms indicative of significant cardiovascular, pulmonary, or metabolic disease(s) during the previous 3 months; * severe lower limb spasticity (Ashworth Scale score ≥ 3); * Botulinum toxin use in the affected lower limb within the past six months; * current or previous use of drugs intended to resolve post-stroke fatigue; * active engagement in other stroke rehabilitation trials.

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Conditions

The condition(s) this trial relates to.

stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • The Hong Kong Polytechnic University

    RECRUITING

    Kowloon, Hong Kong

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