Vaccine-Brain link under the microscope: new study seeks answers
NCT ID NCT04992195
First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 2 times
Summary
This study aims to understand if COVID-19 vaccines have any impact on brain health in healthy people. Researchers will use MRI scans to look for changes in the brain's blood vessels and structure. The study will follow 500 adults from Hong Kong who have already had a baseline brain scan. By comparing scans before and after vaccination, the team hopes to provide clear, evidence-based information to address safety concerns.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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415 people
The number who actually took part.
- Started
-
Jul 2021
- Finished
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Mar 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
1\. Chinese ONLY 2. Hong Kong Resident
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: All consecutive citizens in the CUHK Brain Health Longitudinal Study cohort who received baseline MRI brain. Exclusion Criteria: 1. Citizens with clinically evident stroke or dementia prior to recruitment; or 2. Citizens who are unable to provide an informed consent; or 3. Citizen with contraindications to MRI brain, e.g., non-MRI compatible implants, claustrophobia, etc; or 4. Citizens who had no baseline MRI brain assessment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Chinese University of Hong Kong
Hong Kong, Hong Kong
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Other studies related to the condition(s) this trial covers.
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