Chinese University Of Hong Kong

This small pilot study is testing whether a new probiotic and prebiotic blend (SCV09) can improve behavioral symptoms and daily functioning in people with Alzheimer's disease. Researchers are enrolling 30 older adults in Hong Kong to take the formula daily for 12 weeks, tracking …

This study aims to find out if a standard clot-busting drug (IV thrombolysis) is safe and effective for stroke patients who are already taking newer blood thinners (DOACs). Current guidelines often prevent these patients from receiving this time-sensitive treatment. Researchers w…

This study is testing whether a non-invasive brain stimulation treatment called transcranial pulse stimulation (TPS) can help people with early Alzheimer's disease. Forty participants will receive either the real treatment or a sham version over several weeks. Researchers will me…

This trial is testing if adding targeted radiation or surgery to the standard drug osimertinib helps people with advanced lung cancer live longer without their cancer getting worse. It's for patients whose cancer has a specific genetic change (EGFR mutation) and who have only a f…

This study is testing a new robotic surgery system with an extra 'fifth arm' for patients with stomach cancer. Ten patients in Hong Kong and Japan will have their cancer removed using this experimental robotic system. The main goals are to see if the surgery can be completed succ…

This study is testing if adding a specific type of water pill (a thiazide diuretic) helps lower high blood pressure in people who use peritoneal dialysis for kidney failure. It involves 40 participants who will take the pill for 90 days, then stop for a period, to compare the eff…

This study is testing a new flexible medical tool called the SpydrBlade Flex during a procedure to treat achalasia, a disorder that makes swallowing difficult. The goal is to see if this tool makes the minimally invasive procedure safer and more effective for patients. Researcher…

This study is testing whether adding a special collagen patch during surgery helps people recover better from a torn Achilles tendon. Researchers will compare surgery with the patch to standard surgery without it in 48 adults. They will check how well the tendon heals and how muc…

This study compares two advanced medical techniques for accessing the bile duct when the standard method fails during a common endoscopic procedure (ERCP). Researchers will randomly assign 188 adult patients who have difficult bile duct access to receive either an ultrasound-guid…

This study is testing a new robotic surgery system, the Medtronic Hugo, for removing chest cancers. It will enroll 50 patients to see how safe and effective the system is for these operations. The main goals are to see how often surgeons need to switch to a different method durin…

This study is testing whether a non-surgical treatment using focused sound waves (HIFU) works as well as traditional surgery (myomectomy) for women with symptomatic uterine fibroids. Researchers will compare how much each treatment improves quality of life, reduces symptoms like …

This study is testing whether combining a precise, high-dose radiation technique with two immunotherapy drugs can help people with advanced liver cancer that has spread into a major vein. It aims to improve survival for patients who currently have very poor outcomes, with a media…

This study is testing if a medication commonly used for diabetes (a GLP-1 agonist) can safely slow down or prevent the worsening of cerebral small vessel disease (cSVD), a condition that damages tiny blood vessels in the brain and can lead to stroke, dementia, and walking problem…

This study is testing if a newer oral pill (Vonoprazan) works as well as the current standard treatment—a high-dose intravenous (IV) drip—for preventing a bleeding stomach ulcer from starting to bleed again. It involves nearly 600 adults who have just had a bleeding ulcer success…

This study is testing whether a telemedicine system can help people with well-controlled high blood pressure maintain their health as effectively as regular in-person doctor visits. Researchers will compare two groups of 364 participants over 12 months: one using an app for remot…

This study is testing whether adding focused radiation therapy can help control advanced liver cancer that has started to progress in a few spots while patients are on standard immunotherapy. Researchers want to see if zapping these specific progressing areas with radiation can h…

This study compares two surgical techniques for repairing macular holes, a condition that can cause permanent central vision loss. The standard surgery uses a gas bubble and requires patients to maintain a face-down position for days afterward. The new technique uses a different …

This study is testing a procedure that uses heat to destroy tumors in the stomach, liver, kidney, or adrenal glands. It is for patients who are not suitable candidates for surgery. Doctors guide a special needle using ultrasound to apply heat directly to the tumor. The main goal …

This study is testing whether a medication called baricitinib can help repair existing bone damage in people with active rheumatoid arthritis. Sixty adult patients with active arthritis and visible bone erosion will take either the real drug or a placebo pill daily for 24 weeks. …

This 5-year study is testing if a common diabetes medication, dapagliflozin, can prevent serious liver complications like cancer and liver failure in people who have both chronic hepatitis B and diabetes. About 412 participants will be randomly assigned to take either the real dr…

This study is testing if a lower dose of a medication (tPA) injected into the chest works as well as the standard dose for treating serious lung infections with fluid buildup. It aims to see if the lower dose can clear the infection effectively while possibly reducing the risk of…

This large study aims to settle a common medical dilemma: whether heart patients should continue or stop their daily aspirin before a colonoscopy. Researchers will compare two groups of over 2,500 patients to see which approach leads to fewer heart problems or serious bleeding ev…

This study compares two emergency treatments for severe stomach bleeding that continues after initial attempts to stop it. Researchers are testing whether special endoscopic clips placed during a scope procedure work as well as blocking the bleeding artery through a catheter. The…

This study is testing a new AI system designed to help surgeons during a minimally invasive procedure to remove early-stage cancers in the digestive tract. The AI provides real-time guidance, highlighting safe areas to cut and warning of risks like blood vessels, aiming to make t…

This small pilot study is testing a new type of brace for teenagers with mild to moderate scoliosis. The brace uses air pads that can be adjusted while the patient is inside an MRI scanner, allowing doctors to see and apply corrective pressure in real time. The goal is to see if …

This study is testing if adding a special stent during emergency surgery for a torn aorta (aortic dissection) leads to better long-term results. It will compare the standard surgery to the same surgery plus the stent implant in 72 patients. The main goal is to see if the stent re…

This study offers a fertility preservation option for young female cancer patients. It involves surgically removing and freezing a piece of ovarian tissue before cancer treatments like chemotherapy, which can damage fertility. The frozen tissue can later be transplanted back to p…

This study aims to use artificial intelligence (AI) to create a personalized plan for stroke recovery. Researchers will gather detailed health data from 400 stroke survivors to train an AI system. The goal is for the AI to predict which type of rehabilitation therapy—like standar…

This study is testing a procedure that uses heat to destroy solid pancreatic tumors. It is for patients with pancreatic cancer or neuroendocrine tumors who are not suitable candidates for surgery. Doctors use an ultrasound-guided needle to apply radiofrequency energy to heat and …

This study is testing whether a digital platform called JCTH+ can help university students manage anxiety and depression better than the usual campus support services. Around 1,700 students in Hong Kong with moderate to severe symptoms will use the platform, which offers self-hel…

This study compares two common treatments for early psoriatic arthritis to see which one is better at preventing permanent joint damage. It will enroll 108 adults who have had symptoms for two years or less and have not yet tried these specific medications. Researchers will use d…

This study is testing a new, personalized approach to find effective treatments for patients with advanced liver or colorectal cancer that has stopped responding to standard therapies. Doctors will grow miniature 3D models of a patient's own tumor in the lab to test how it respon…

This study is testing if a simple wall squat exercise program can help lower high blood pressure in Chinese adults who don't get enough physical activity. 390 participants with high blood pressure will be randomly assigned to either do wall squats or stretching exercises for 24 w…

This study is testing a comprehensive 3-year care program for Chinese adults who have both diabetes and obesity (diabesity). The program uses a team of specialists, including a doctor, dietitian, and psychologist, along with technology like an AI chatbot and peer support. The mai…

This study is testing if a special diet containing medium-chain triglycerides (MCTs) can help patients recover faster after lung surgery. Researchers will give the MCT diet to some patients after their operation to see if it reduces fluid buildup and shortens their hospital stay …

This study is testing whether a personalized support program helps smokers who have cancer quit. About 1,450 participants in Hong Kong will either get brief advice to quit immediately or get to choose their own quit date and receive encouraging text messages for 6 months. The goa…

This study is testing if a newer, ultrasound-guided endoscopic procedure is better than standard treatment at preventing dangerous variceal re-bleeding in people with liver cancer (HCC). It will enroll 84 patients who have recently had a bleeding episode controlled. The main goal…

This pilot study is testing an online therapy program designed to help people quit smoking while also managing feelings of stress, anxiety, or depression. The program teaches skills based on a therapy called Dialectical Behaviour Therapy. Researchers will recruit 60 adult smokers…

This study is testing if more frequent monitoring and quicker adjustments to cholesterol-lowering medication can help heart disease patients reach their treatment goals. It will enroll 1,000 adults with heart disease to see if this approach lowers 'bad' cholesterol more effective…

This study aims to find the best endoscopic method to remove small, early-stage stomach tumors called GISTs. It will compare two minimally invasive techniques—EFTR and STER—to see which one more completely removes the tumor while keeping patients safe. About 136 adults with small…

This study is testing whether an online therapy program for social anxiety disorder works just as well when guided by a trained coach instead of a clinical psychologist. It aims to make effective treatment more accessible and affordable. About 110 adults in Hong Kong with social …

This study is testing a simpler, lower-cost method to help eggs mature outside the body for women with infertility. It aims to help women who have trouble getting pregnant naturally, including those who need to preserve their fertility before cancer treatment. The method is desig…

This study is testing a new, potentially safer method to measure pressure inside the liver (portal hypertension) in people with cirrhosis from chronic hepatitis. The goal is to see if this new method, done during a standard scope exam, can accurately predict a patient's risk of s…

This study is testing a new skin test to find hidden tuberculosis (TB) in people with arthritis before they start certain powerful arthritis medications. Researchers will compare the new test to standard tests in 100 patients to see how well it works. The goal is to improve early…

This study is testing a new artificial intelligence (AI) tool designed to automatically spot and measure aortic regurgitation, which is a leak in the heart's main valve. It will compare the AI's accuracy and speed against the standard method where doctors manually analyze heart u…

This study is testing a new blood test called HerResolve™ that aims to detect endometriosis without surgery. Researchers will compare the blood test results to findings from laparoscopic surgery in 100 women aged 18-49 who have pelvic pain symptoms. The goal is to see if this non…

This study is testing a new, very fast type of MRI scan designed to detect early liver scarring (fibrosis) without the need for a painful biopsy. Researchers will compare the scan's results to both the current gold-standard biopsy and another non-invasive scan in 200 adults with …

This small pilot study is testing whether a camera procedure to check for returning kidney cancer can be done safely using only local numbing gel, without putting patients to sleep with general anesthesia. It will involve 10 people who have previously had surgery to remove a spec…

This study is comparing two different methods for performing prostate biopsies in men who have a suspicious area on an MRI scan. It aims to find out which method—using a computer to fuse the MRI with ultrasound images or relying on the doctor's mental map—is better at finding ser…

This study is testing if a proactive health program can help prevent chronic diseases. Researchers are enrolling over 1,100 people visiting emergency rooms in Hong Kong who have at least one unhealthy habit. One group gets personalized health advice, weekly text/chat reminders, a…

This study is testing a digital sleep program designed to prevent chronic insomnia in adults who currently have only mild sleep problems. Over 1,000 adults in Hong Kong will use an online platform that offers different levels of sleep coaching based on their needs. The goal is to…

This study offers ovarian tissue freezing to young female cancer patients (ages 0-35) to preserve their ability to have children later in life. The procedure is designed for patients who need to start cancer treatments like chemotherapy or radiation immediately, as it does not re…

This study is testing whether an 8-week mindfulness course can help teachers feel less stressed and burned out while improving their teaching skills. Researchers will enroll 160 currently working teachers in Hong Kong and randomly assign them to either take the mindfulness course…

This study is testing if a gentle, acupuncture-style electrical stimulation device can cut pain in half for women undergoing egg retrieval for IVF. 144 women will be randomly assigned to receive either the real stimulation or a fake version during the procedure. Researchers will …

This study is testing whether a brief therapy session delivered by an artificial intelligence therapist in virtual reality can help reduce symptoms of depression. It will involve 60 young adults in Hong Kong who report depressive symptoms, comparing the VR therapy to a waiting li…

This study is testing whether a specific nerve block, given during surgery, can improve recovery and reduce the chance of developing long-term pain after heart surgery. Researchers will compare the nerve block to a placebo in 96 adults having planned heart operations. The main go…

This study is testing a mobile phone app designed to help children who have finished cancer treatment manage their ongoing symptoms like fatigue, pain, and anxiety. For 12 weeks, 150 child survivors and their main caregiver will use the app, which includes personalized support fr…

This study is testing whether a fun, game-like music training program can help children from low-income families cope better with stress. 174 children aged 8 to 12 who are at risk for anxiety or depression will be randomly assigned to either take weekly music lessons or participa…

This study is testing a new soft robotic glove designed to help people recover hand and arm movement after a stroke. Sixty stroke survivors will attend training sessions where the glove assists them with different tasks, using their own muscle signals to guide the movement. The g…

This study is testing whether whole-body vibration therapy can help reduce knee pain and improve muscle strength in people who have had surgery to repair a torn ACL. Researchers will enroll 50 adults who have persistent knee pain after their ACL surgery. The goal is to see if thi…

This study is testing whether daily bright light therapy can help improve depression in teenagers who naturally stay up late and sleep in. 90 teens will use either a bright light lamp or a dim placebo lamp each morning for 8 weeks. Researchers will track changes in their mood, sl…

This study is testing a new nurse-led program designed to help children with cancer sleep better. The program teaches kids and their caregivers relaxation exercises and healthy sleep habits, aiming to improve their quality of life during treatment. It's a small pilot study to see…

This study is creating a collection of blood, tissue, and fluid samples from stroke patients and their families. The goal is to store these samples for future research to discover the genetic factors that cause stroke. By understanding these genetics, scientists hope to find bett…

This study aims to better understand the physical features of dangerous plaques in the brain's arteries that can break off and cause strokes. Researchers will compare brain scans from 140 people who have had a stroke with scans from people who have similar plaques but no symptoms…

This study aims to understand what factors lead to brain diseases like stroke and dementia by following 5,000 adults over many years. Participants, including those with a diagnosis, at high risk, or who are healthy, will regularly complete health questionnaires and interviews. Th…

This study aims to understand how well a proven emergency stroke treatment works in everyday hospital practice across the Asia-Pacific region. Researchers will observe 350 adult patients who have a severe stroke caused by a major blocked brain artery. The goal is to identify fact…

This study aims to better understand how fatty liver disease and type 2 diabetes are connected and progress over time. Researchers will follow 1,000 adults in Hong Kong who have both conditions, collecting health data and blood samples to create a detailed registry. The main goal…

This study aims to understand how the community of bacteria and viruses in the nose and throat is connected to different types and severities of adult asthma. Researchers will collect swab samples from 140 adults with asthma and track their health over two years. The goal is to g…

This study aims to observe and collect information on how 500 adults with severe, difficult-to-control asthma in Hong Kong are managed by their doctors over two years. It will track their symptoms, asthma flare-ups, hospital visits, and their experience with newer, expensive biol…

This study aims to learn if a blood test can track how well radiation therapy is working for liver cancer. Researchers will take blood samples from 15 patients before, during, and after their radiation treatment to look for tiny pieces of tumor DNA. The goal is to see if changes …

This study aims to develop a computer prediction tool to identify which patients with Chronic Obstructive Pulmonary Disease (COPD) are most likely to be readmitted to the hospital soon after being discharged. Researchers will analyze the health records of up to 100,000 patients i…

This research study aims to find better treatments for children with leukemia. Researchers will test leukemia cells from 300 children against various targeted drugs to see which ones work best. They will also develop and test new antibody treatments in lab models to prepare for f…

This study aims to understand what women in Hong Kong know about common gynecological problems and what stops them from getting help. Researchers will survey 800 people, including patients and the general public, to compare their knowledge and identify barriers to care. The goal …

This study aims to understand if COVID-19 vaccines affect brain health, specifically looking for signs of stroke or dementia. Researchers in Hong Kong will follow 500 healthy adults, comparing brain scans and memory tests from before and after vaccination to those from unvaccinat…

This study aims to understand how protection against COVID-19 changes within families over time. Researchers will follow 900 households in Hong Kong for 12-18 months, checking blood for antibodies from vaccines and past infections. The goal is to learn how immunity levels in a ho…

This study looks back at medical records to understand how biologic drugs are used to treat severe asthma in Hong Kong. Researchers will review the health data of 360 adults who received these treatments to see how well they worked and how safe they were. The goal is to learn abo…

This study aims to create a detailed health register to understand how diabetes and obesity together affect people's long-term health. It will follow 800 adults in Hong Kong with both conditions, conducting thorough health checks at the start and again after 3 years. The main goa…

This study aims to create a better system for developing safety guidelines about mixing herbal remedies and prescription drugs. Researchers will gather opinions from 40 healthcare experts and policymakers through surveys and interviews. The goal is to understand current challenge…

This study aims to understand how plaque inside the brain's arteries changes shape and size over one year in people who have had a stroke. Researchers will use a detailed 3D imaging scan at the start and after 12 months to closely measure these changes. The goal is to learn more …

This study aims to understand how genetics influence asthma severity and types in Chinese people. Researchers will collect blood samples and health information from 1000 asthma patients and 1000 healthy volunteers. The goal is to identify specific genetic patterns that make some …

This study aims to understand how well different fertility preservation methods work for people whose medical treatments (like cancer therapy) might affect their future ability to have children. Researchers will review the medical records of up to 100 patients who have used these…